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61,005 resultsShowing papers similar to Coexposure of Micro and Nano-Plastics with Pesticides: Cytotoxicity and Bioaccumulation Effects on a Fish Intestinal Cell Line
ClearRole of UV radiation and oxidation on polyethylene micro- and nanoplastics: impacts on cadmium sorption, bioaccumulation, and toxicity in fish intestinal cells
This study examined how UV aging and oxidation change the way polyethylene micro and nanoplastics interact with cadmium, a toxic heavy metal, in fish gut cells. While the plastics actually reduced cadmium absorption and toxicity in the cells, UV aging changed the particles' surface chemistry and caused them to clump together differently. The results suggest that the interaction between microplastics and heavy metals in the environment is complex and depends on how weathered the plastic is.
Toxicity of mixture of polyethylene microplastics and Up Grade® pesticide on Oreochromis niloticus juvenile: I. Hemato-biochemical and histopathological alterations
Researchers exposed juvenile Nile tilapia to a pesticide and polyethylene microplastics, both individually and in combination, and measured blood chemistry changes and organ damage over 15 days. The combination treatment caused more severe effects than either pollutant alone, including reduced red blood cell counts, elevated liver enzymes, and significant tissue damage to the gills and intestines. The study demonstrates that microplastics can worsen the toxic effects of agricultural pesticides on commercially important fish species.
Adsorption behaviors of chlorpyrifos on UV aged microplastics
Researchers investigated how UV aging affects the adsorption of the pesticide chlorpyrifos on biodegradable and non-degradable microplastics, finding that UV irradiation significantly modified plastic surfaces and enhanced their capacity to carry organic pollutants.
UV-Aged Nanoplastics Increase Mercury Toxicity in a Marine Copepod under Multigenerational Exposure: A Carrier Role
Researchers found that UV-aged nanoplastics were much better at carrying mercury into the bodies of marine copepods than fresh nanoplastics, increasing mercury accumulation by over 50% across multiple generations. The combination of aged nanoplastics and mercury significantly reduced survival rates in offspring. Since most nanoplastics in the ocean have been weathered by sunlight, this study suggests the real-world risks of nanoplastic-metal combinations to marine food chains may be greater than lab studies with fresh plastics indicate.
Influence of ultraviolet-aging and adsorbed pollutants on toxicological effects of polyvinyl chloride microplastics to zebrafish
Researchers studied how UV aging changes polyvinyl chloride microplastics and their toxicity to zebrafish, both alone and when carrying adsorbed pollutants. They found that aged microplastics caused more severe gut damage and oxidative stress than pristine particles, due to increased free radicals on their surfaces. When carrying adsorbed chlorpyrifos or erythromycin, the microplastics served as pollutant carriers into fish, producing greater behavioral disruption and gut microbiome alterations.
Single and combined effects of polyethylene microplastics and acetochlor on accumulation and intestinal toxicity of zebrafish (Danio rerio)
This study found that polyethylene microplastics significantly increased the toxicity of acetochlor, a common herbicide, in zebrafish. The microplastics boosted the accumulation of the pesticide in fish tissues and worsened intestinal damage including inflammation and disrupted gut barrier function. The findings are important because microplastics and pesticides frequently co-exist in agricultural waterways, and their combination may pose greater risks than either pollutant alone.
Effects of single and combined exposure of virgin or aged polyethylene microplastics and penthiopyrad on zebrafish (Danio rerio)
This study found that polyethylene microplastics can increase the toxicity of a common fungicide (penthiopyrad) in zebrafish by helping the chemical build up in their bodies. The combination caused more intestinal damage and disrupted gut bacteria than either pollutant alone. This highlights an important concern: microplastics in the environment can act as carriers for pesticides, potentially amplifying their harmful effects on organisms including those in the human food chain.
Laboratory Studies about Microplastic Aging and Its Effects on the Adsorption of Chlorpyrifos
Researchers simulated the aging of six types of microplastics in freshwater and seawater to study how weathering affects their ability to adsorb the pesticide chlorpyrifos. The study found that UV-driven aging caused surface cracks, pores, and chemical changes in the microplastics, and the aging process increased their capacity to adsorb chlorpyrifos, suggesting that weathered microplastics in the environment may carry higher concentrations of pesticide pollutants.
Combined toxic effects of polyethylene microplastics and lambda-cyhalothrin on gut of zebrafish (Danio rerio)
Researchers found that polyethylene microplastics can adsorb the pesticide lambda-cyhalothrin from water and then release it in the guts of zebrafish, worsening its toxic effects. Fish exposed to both microplastics and the pesticide showed greater oxidative stress, immune disruption, and gut microbiome changes than those exposed to the pesticide alone. This demonstrates how microplastics can act as carriers that amplify the toxicity of other environmental pollutants in aquatic organisms consumed by humans.
Insights into the effects of aging on the combined toxicity of polystyrene nanoplastics and chlordane against Caenorhabditis elegans
Researchers studied how environmental aging of polystyrene nanoplastics changes their combined toxicity with the pesticide chlordane in roundworms. They found that photo-aging altered the physical and chemical properties of the nanoplastics, which in turn modified how the two contaminants interacted and their joint toxic effects. The study highlights that the environmental weathering of plastic particles can significantly change how they interact with other pollutants.
Adsorption behavior of triazine pesticides on polystyrene microplastics aging with different processes in natural environment
Researchers found that microplastics that have aged in the environment absorb pesticides more effectively and quickly than fresh microplastics, and the pesticide-loaded particles are more toxic to bacteria. This means that as microplastics weather outdoors, they become better carriers for agricultural chemicals, potentially increasing the combined health risks when these contaminated particles enter food or water supplies.
Effects of microplastics on the toxicity of co-existing pollutants to fish: A meta-analysis
Meta-analysis of 1,380 biological endpoints from 55 studies found that microplastics in co-existing pollutant solutions significantly increased toxicity to fish beyond what the pollutants caused alone, particularly elevating immune system damage, metabolic disruption, and oxidative stress. The effect depended on fish life stage and microplastic size, but not on pollutant or polymer type.
Polymer aging affects the bioavailability of microplastics-associated contaminants in sea urchin embryos
Researchers found that UV aging of microplastics alters the bioavailability of co-contaminants like flame retardants and metals to sea urchin embryos, with combined exposures generating transcriptional responses distinct from single-contaminant effects.
Combined neurotoxicity of aged microplastics and thiamethoxam in the early developmental stages of zebrafish (Danio rerio)
This study found that aged (weathered) microplastics combined with the insecticide thiamethoxam caused worse neurological damage to zebrafish larvae than either pollutant alone. The combined exposure reduced heart rate and movement, disrupted antioxidant defenses, and altered neurotransmitter levels in ways that were synergistic rather than simply additive. This is relevant to human health because both microplastics and pesticides are common in the environment, and their combined effects may pose greater risks than either one individually.
The role of microplastic aging on chlorpyrifos adsorption-desorption and microplastic bioconcentration
Researchers investigated how microplastic aging affects chlorpyrifos adsorption-desorption behavior, finding that aged microplastics had higher pesticide sorption capacity and bioconcentration potential, suggesting weathered MPs pose greater risks as pollutant carriers.
Co-exposure toxicity of microplastic and sumithion in Nile tilapia – changes in growth, hematology, histopathology of internal tissues and immune-antioxidant genes expression
Researchers studied the combined effects of polyamide microplastics and the pesticide sumithion on Nile tilapia, a widely farmed fish species. They found that co-exposure reduced growth, disrupted blood parameters, caused tissue damage in gills and intestines, and altered immune and antioxidant gene expression more severely than either pollutant alone. The study highlights that microplastics and pesticides together may pose amplified threats to fish health in contaminated aquaculture environments.
Detrimental effects of individual versus combined exposure to tetrabromobisphenol A and polystyrene nanoplastics in fish cell lines
Researchers tested how combined exposure to the flame retardant tetrabromobisphenol A and polystyrene nanoparticles affects freshwater fish cells. They found that co-exposure to even low concentrations of both pollutants caused subtle changes in cell viability and generated oxidative DNA damage. The study suggests that the interaction between nanoplastics and chemical pollutants in aquatic environments may pose compounding risks to fish health.
Aging amplifies the combined toxic effects of polystyrene nanoplastics and norfloxacin on human intestinal cells
Researchers investigated how environmental aging of polystyrene nanoplastics affects their combined toxicity with the antibiotic norfloxacin on human intestinal cells. They found that aged nanoplastics were taken up more readily by cells and significantly amplified the harmful effects of the antibiotic, including increased cell damage. The study suggests that weathered nanoplastics in the environment may pose greater health risks than fresh particles, especially when combined with other contaminants.
Synergistic neurotoxicity of clothianidin and photoaged microplastics in zebrafish: Implications for neuroendocrine disruption
This study found that photoaged (sun-weathered) microplastics absorb more of the insecticide clothianidin than fresh plastics, and the combination caused greater nerve damage in zebrafish larvae than either pollutant alone. The results demonstrate how weathered microplastics in the environment can amplify the toxicity of other chemicals they encounter, creating compound exposure risks for aquatic life and potentially for humans through the food chain.
The neurodevelopmental toxicity induced by combined exposure of nanoplastics and penicillin in embryonic zebrafish: The role of aging processes
Researchers studied how nanoplastics combined with the antibiotic penicillin affect brain development in zebrafish embryos, including how aging of the nanoplastics changes their toxicity. They found that pristine and UV-aged nanoplastics combined with penicillin caused more severe neurodevelopmental harm than either substance alone, suppressing heartbeat and movement. The findings suggest that environmental aging of nanoplastics can alter their interactions with common pollutants like antibiotics, potentially increasing risks to developing organisms.
Toxicological interactions of microplastics/nanoplastics and environmental contaminants: Current knowledge and future perspectives
This review examines how the combined presence of micro- and nanoplastics with other environmental contaminants like heavy metals, pesticides, and pharmaceuticals affects toxicity. Researchers found that plastic particles can alter the bioavailability and toxic effects of co-occurring pollutants, sometimes increasing harm to organisms, which complicates environmental risk assessment.
Interactions Between Various Classes of Pesticides and Microplastics
This review summarized how microplastics interact with pesticides from multiple chemical classes, covering adsorption, desorption, environmental transport, and combined toxicity. The authors found that microplastic-pesticide interactions are governed by both the plastic's surface chemistry and the pesticide's physicochemical properties, and that combined exposures often amplify toxicity beyond either contaminant alone.
Evaluation of Detoxification‐Related Gene Expression, Oxidative Stress Biomarkers, and Blood Biochemical Parameters in Common Carp ( Cyprinus carpio ) Co‐Exposed to Polyethylene Microplastics and Deltamethrin
Researchers investigated whether polyethylene microplastics worsen the toxic effects of the insecticide deltamethrin in juvenile common carp over a 30-day exposure. The study found that co-exposure to microplastics and deltamethrin affected detoxification-related gene expression, oxidative stress biomarkers, and blood biochemistry, suggesting that microplastics can modify the bioavailability and toxicity of co-occurring pesticides in fish.
Interaction behavior, mechanisms and hazardous changes of microplastics on single and binary component pesticide in the environment and food: Diethofencarb and pyrimethanil
Researchers studied how four types of microplastics absorb two common pesticides and found that the plastics acted as carriers that increased the pesticides' bioavailability during simulated human digestion. The adsorption was faster when both pesticides were present together, and more water-repellent pesticides bound more readily to the plastics. This is concerning because it means microplastics in food could deliver higher doses of pesticide residues into the body than the pesticides would on their own.