We can't find the internet
Attempting to reconnect
Something went wrong!
Hang in there while we get back on track
Combined toxic effects of polyethylene microplastics and lambda-cyhalothrin on gut of zebrafish (Danio rerio)
AI summary Read the abstract
Researchers found that polyethylene microplastics can adsorb the pesticide lambda-cyhalothrin from water and then release it in the guts of zebrafish, worsening its toxic effects. Fish exposed to both microplastics and the pesticide showed greater oxidative stress, immune disruption, and gut microbiome changes than those exposed to the pesticide alone. This demonstrates how microplastics can act as carriers that amplify the toxicity of other environmental pollutants in aquatic organisms consumed by humans.
Microplastics (MPs), which are prevalent and increasingly accumulating in aquatic environments. Other pollutants coexist with MPs in the water, such as pesticides, and may be carried or transferred to aquatic organisms, posing unpredictable ecological risks. This study sought to assess the adsorption of lambda-cyhalothrin (LCT) by virgin and aged polyethylene MPs (VPE and APE, respectively), and to examine their influence on LCT's toxicity in zebrafish, specifically regarding acute toxicity, oxidative stress, gut microbiota and immunity. The adsorption results showed that VPE and APE could adsorb LCT, with adsorption capacities of 34.4 mg∙g and 39.0 mg∙g, respectively. Compared with LCT exposure alone, VPE and APE increased the acute toxicity of LCT to zebrafish. Additionally, exposure to LCT and PE-MPs alone can induce oxidative stress in the zebrafish gut, while combined exposure can exacerbate the oxidative stress response and intensify intestinal lipid peroxidation. Moreover, exposure to LCT or PE-MPs alone promotes inflammation, and combined exposure leads to downregulation of the myd88-nf-κb related gene expression, thus impacting intestinal immunity. Furthermore, exposure to APE increased LCT toxicity to zebrafish more than VPE. Meanwhile, exposure to PE-MPs and LCT alone or in combination has the potential to affect gut microbiota function and alter the abundance and diversity of the zebrafish gut flora. Collectively, the presence of PE-MPs may affect the toxicity of pesticides in zebrafish. The findings emphasize the importance of studying the interaction between MPs and pesticides in the aquatic environment.
More Papers Like This
Effects of single and combined exposure of virgin or aged polyethylene microplastics and penthiopyrad on zebrafish (Danio rerio)
AI summary Read the abstract
This study found that polyethylene microplastics can increase the toxicity of a common fungicide (penthiopyrad) in zebrafish by helping the chemical build up in their bodies. The combination caused more intestinal damage and disrupted gut bacteria than either pollutant alone. This highlights an important concern: microplastics in the environment can act as carriers for pesticides, potentially amplifying their harmful effects on organisms including those in the human food chain.
Single and combined effects of polyethylene microplastics and acetochlor on accumulation and intestinal toxicity of zebrafish (Danio rerio)
AI summary Read the abstract
This study found that polyethylene microplastics significantly increased the toxicity of acetochlor, a common herbicide, in zebrafish. The microplastics boosted the accumulation of the pesticide in fish tissues and worsened intestinal damage including inflammation and disrupted gut barrier function. The findings are important because microplastics and pesticides frequently co-exist in agricultural waterways, and their combination may pose greater risks than either pollutant alone.
Co-exposure to polystyrene microplastics and cypermethrin enhanced the effects on hepatic phospholipid metabolism and gut microbes in adult zebrafish
AI summary Read the abstract
When zebrafish were exposed to both polystyrene microplastics and the pesticide cypermethrin together, the combination caused significantly more liver damage than either pollutant alone. The mixture disrupted fat metabolism in the liver and altered gut bacteria in ways not seen with individual exposures. This matters because microplastics and pesticides frequently co-exist in waterways, and their combined effects on fish health could affect the safety of fish as food.
Toxicological effects of microplastics and phenanthrene to zebrafish (Danio rerio)
AI summary Read the abstract
Researchers exposed zebrafish to polystyrene microplastics, the pollutant phenanthrene, and a combination of both to assess their toxicity over 24 days. They found that co-exposure amplified oxidative stress, suppressed immune gene expression, and significantly disrupted the gut microbiome compared to either contaminant alone. The study suggests that microplastics can worsen the toxic effects of organic pollutants in aquatic organisms by altering how chemicals accumulate and interact in the body.
Combined effects of polyethylene terephthalate and abamectin on enzymatic activity and histopathology response in juvenile zebrafish (Danio rerio)
AI summary Read the abstract
Researchers studied the combined effects of PET microplastic fragments and the pesticide abamectin on juvenile zebrafish over 96 hours. They found that microplastics increased the bioavailability and toxicity of the pesticide by inhibiting protective enzymes in the fish, and the combination caused tissue damage in the liver and kidney. The study highlights that microplastics can act as carriers for other environmental contaminants, amplifying their harmful effects on aquatic life.
Research digests by email
When a large batch of papers lands in the Atlas, we read through it and send a short write-up of what stood out.