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Toxicity of mixture of polyethylene microplastics and Up Grade® pesticide on Oreochromis niloticus juvenile: I. Hemato-biochemical and histopathological alterations

Environmental Toxicology and Pharmacology 2023 21 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count. Score: 55 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.
Ibrahim Mohamed, Alaa El‐Din H. Sayed Alaa El‐Din H. Sayed Alaa El‐Din H. Sayed Alaa El‐Din H. Sayed Alaa El‐Din H. Sayed Alaa El‐Din H. Sayed Alaa El‐Din H. Sayed Alaa El‐Din H. Sayed Alaa El‐Din H. Sayed Alaa El‐Din H. Sayed Hamdy A. M. Soliman, Alaa El‐Din H. Sayed Hamdy A. M. Soliman, Hamdy A. M. Soliman, Hamdy A. M. Soliman, Hamdy A. M. Soliman, Alaa El‐Din H. Sayed Alaa El‐Din H. Sayed Alaa El‐Din H. Sayed Alaa El‐Din H. Sayed Hamdy A. M. Soliman, Hamdy A. M. Soliman, Hamdy A. M. Soliman, Alaa El‐Din H. Sayed Jae‐Seong Lee, Alaa El‐Din H. Sayed Alaa El‐Din H. Sayed Alaa El‐Din H. Sayed Alaa El‐Din H. Sayed Alaa El‐Din H. Sayed Jae‐Seong Lee, Jae‐Seong Lee, Jae‐Seong Lee, Jae‐Seong Lee, Mervat Hana, Mervat Hana, Hamdy A. M. Soliman, Alaa El‐Din H. Sayed Alaa El‐Din H. Sayed Alaa El‐Din H. Sayed Hamdy A. M. Soliman, Alaa El‐Din H. Sayed Alaa El‐Din H. Sayed Alaa El‐Din H. Sayed Alaa El‐Din H. Sayed Alaa El‐Din H. Sayed Alaa El‐Din H. Sayed Alaa El‐Din H. Sayed Jae‐Seong Lee, Jae‐Seong Lee, Jae‐Seong Lee, Jae‐Seong Lee, Jae‐Seong Lee, Jae‐Seong Lee, Jae‐Seong Lee, Jae‐Seong Lee, Jae‐Seong Lee, Jae‐Seong Lee, Hamdy A. M. Soliman, Hamdy A. M. Soliman, Alaa El‐Din H. Sayed Jae‐Seong Lee, Alaa El‐Din H. Sayed Jae‐Seong Lee, Jae‐Seong Lee, Jae‐Seong Lee, Jae‐Seong Lee, Jae‐Seong Lee, Jae‐Seong Lee, Alaa El‐Din H. Sayed Hamdy A. M. Soliman, Alaa El‐Din H. Sayed Jae‐Seong Lee, Jae‐Seong Lee, Alaa El‐Din H. Sayed Jae‐Seong Lee, Jae‐Seong Lee, Jae‐Seong Lee, Alaa El‐Din H. Sayed Alaa El‐Din H. Sayed Alaa El‐Din H. Sayed Alaa El‐Din H. Sayed Jae‐Seong Lee, Alaa El‐Din H. Sayed Alaa El‐Din H. Sayed Jae‐Seong Lee, Jae‐Seong Lee, Jae‐Seong Lee, Jae‐Seong Lee, Jae‐Seong Lee, Jae‐Seong Lee, Jae‐Seong Lee, Alaa El‐Din H. Sayed Jae‐Seong Lee, Jae‐Seong Lee, Jae‐Seong Lee, Jae‐Seong Lee, Hamdy A. M. Soliman, Alaa El‐Din H. Sayed Jae‐Seong Lee, Jae‐Seong Lee, Jae‐Seong Lee, Jae‐Seong Lee, Jae‐Seong Lee, Hamdy A. M. Soliman, Alaa El‐Din H. Sayed Jae‐Seong Lee, Jae‐Seong Lee, Jae‐Seong Lee, Jae‐Seong Lee, Jae‐Seong Lee, Jae‐Seong Lee, Jae‐Seong Lee, Jae‐Seong Lee, Alaa El‐Din H. Sayed Jae‐Seong Lee, Jae‐Seong Lee, Jae‐Seong Lee, Jae‐Seong Lee, Jae‐Seong Lee, Jae‐Seong Lee, Alaa El‐Din H. Sayed Jae‐Seong Lee, Jae‐Seong Lee, Alaa El‐Din H. Sayed Jae‐Seong Lee, Jae‐Seong Lee, Alaa El‐Din H. Sayed

Summary

Researchers exposed juvenile Nile tilapia to a pesticide and polyethylene microplastics, both individually and in combination, and measured blood chemistry changes and organ damage over 15 days. The combination treatment caused more severe effects than either pollutant alone, including reduced red blood cell counts, elevated liver enzymes, and significant tissue damage to the gills and intestines. The study demonstrates that microplastics can worsen the toxic effects of agricultural pesticides on commercially important fish species.

Polymers

Acute toxicity experiments were conducted to determine the lethal concentration 50 (LC50) of the Up Grade®46% SL for Oreochromis niloticus. Our results showed that the 96-h LC50 value of UPGR for O. niloticus was 29.16 mg L-1. To study hemato-biochemical effects, fish were exposed for 15 days to individual UPGR at 2.916 mg L-1, individual polyethylene microplastics (PE-MPs) at 10 mg L-1, and to their combinations UPGR+PE-MPs. UPGR exposure induced significant decrease in account of red blood cells (RBCs) and white blood cells (WBCs), platelets, monocytes, neutrophils, eosinophils, and the concentrations of hemoglobin (Hb), hematocrit (Hct), and mean corpuscular hemoglobin concentration (MCHC) than other treatments, compared to the control group. Sub-acute UPGR exposure significantly increase lymphocytes, mean corpuscular volume (MCV), and mean corpuscular hemoglobin (MCH), compared to the control group. In conclusion, UPGR and PE-MPs displayed antagonistic toxic effects due to maybe the sorption of UPGR onto PE-MPs.

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