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61,005 resultsShowing papers similar to Combined impacts of organophosphate pesticide and polyamide microplastics on growth, hematology, and immune responses in juvenile striped catfish (Pangasianodon hypophthalmus)
ClearCo-exposure toxicity of microplastic and sumithion in Nile tilapia – changes in growth, hematology, histopathology of internal tissues and immune-antioxidant genes expression
Researchers studied the combined effects of polyamide microplastics and the pesticide sumithion on Nile tilapia, a widely farmed fish species. They found that co-exposure reduced growth, disrupted blood parameters, caused tissue damage in gills and intestines, and altered immune and antioxidant gene expression more severely than either pollutant alone. The study highlights that microplastics and pesticides together may pose amplified threats to fish health in contaminated aquaculture environments.
Toxicity of mixture of polyethylene microplastics and Up Grade® pesticide on Oreochromis niloticus juvenile: I. Hemato-biochemical and histopathological alterations
Researchers exposed juvenile Nile tilapia to a pesticide and polyethylene microplastics, both individually and in combination, and measured blood chemistry changes and organ damage over 15 days. The combination treatment caused more severe effects than either pollutant alone, including reduced red blood cell counts, elevated liver enzymes, and significant tissue damage to the gills and intestines. The study demonstrates that microplastics can worsen the toxic effects of agricultural pesticides on commercially important fish species.
Single and Combined Effects of Microplastics and Cadmium on the Cadmium Accumulation and Biochemical and Immunity of Channa argus
Researchers investigated the single and combined effects of microplastics and cadmium on juvenile snakehead fish, finding that co-exposure caused greater tissue damage, oxidative stress, and immune disruption than either pollutant alone.
Combined effects of polystyrene microplastics and cadmium on oxidative stress, apoptosis, and GH/IGF axis in zebrafish early life stages
Researchers exposed zebrafish embryos to polystyrene microplastics and cadmium, both alone and together, and found that the combination caused significantly worse effects than either pollutant individually. Co-exposure amplified oxidative stress, increased cell death in the spine and esophagus, and disrupted growth hormone pathways more severely than single exposures. The findings suggest that microplastics and heavy metals in waterways may interact to create heightened risks for developing fish.
Toxic effects of polystyrene microplastics on atrazine in zebrafish: Exogenous toxicity and endogenous mechanism
Researchers found that combining polystyrene microplastics with the common herbicide atrazine was more toxic to zebrafish than either pollutant alone, causing greater liver and gut damage. The combination also degraded water quality by reducing oxygen levels and increasing harmful nitrogen compounds. This is important because microplastics and pesticides frequently co-exist in the environment, meaning their combined effects on aquatic life and food safety may be worse than studies of individual pollutants suggest.
Combined effects of microplastics and benzo[a]pyrene on Asian sea bass Lates calcarifer growth and expression of functional genes
Researchers exposed juvenile Asian sea bass to polyethylene microplastics and the carcinogen benzo[a]pyrene, both individually and in combination, over 56 days. They found that co-exposure caused more severe effects on growth and gene expression related to immune function and stress response than either contaminant alone. The study highlights that microplastics may worsen the toxic effects of chemical pollutants already present in marine environments.
Single and combined effects of microplastics and cadmium on juvenile grass carp (Ctenopharyngodon idellus)
Researchers found that combined exposure to polystyrene microplastics and cadmium in juvenile grass carp caused greater physiological stress than either pollutant alone, with microplastics enhancing cadmium accumulation and intensifying oxidative stress and immune responses.
Combined neurotoxicity of aged microplastics and thiamethoxam in the early developmental stages of zebrafish (Danio rerio)
This study found that aged (weathered) microplastics combined with the insecticide thiamethoxam caused worse neurological damage to zebrafish larvae than either pollutant alone. The combined exposure reduced heart rate and movement, disrupted antioxidant defenses, and altered neurotransmitter levels in ways that were synergistic rather than simply additive. This is relevant to human health because both microplastics and pesticides are common in the environment, and their combined effects may pose greater risks than either one individually.
Individual and combined effects of microplastics and diphenyl phthalate as plastic additives on male goldfish: A biochemical and physiological investigation
Male goldfish exposed to both microplastics and the plasticizer chemical DPP (diphenyl phthalate) together showed significant liver damage, disrupted fat and sugar metabolism, and hormonal imbalances including decreased testosterone and increased estrogen. The combined exposure was more harmful than either pollutant alone, demonstrating how microplastics and their chemical additives can work together to disrupt the endocrine system.
A realistic combined exposure scenario: effect of microplastics and atrazine on Piaractus mesopotamicus
Scientists studied the combined effects of polyethylene microplastics and the herbicide atrazine on juvenile pacu fish in a realistic exposure scenario. Researchers found that the combination of these contaminants caused tissue damage and biochemical changes, including altered enzyme activity and genetic damage. The study suggests that microplastics and agricultural chemicals together may pose greater risks to freshwater fish than either pollutant alone.
Toxicity of co-exposure of microplastics and lead in African catfish (Clarias gariepinus)
Researchers exposed African catfish to lead, microplastics, and a combination of both for 15 days and found that the combined exposure was more harmful than either pollutant alone. The mixture caused the greatest damage to blood cells, triggered stronger inflammatory responses, and disrupted the fish's antioxidant defenses. Since microplastics can carry heavy metals like lead on their surfaces, this study shows how microplastics may amplify the toxic effects of other pollutants in freshwater fish that people eat.
Combined exposure to polystyrene nanoplastics and bisphenol A induces hepato- and intestinal-toxicity and disturbs gut microbiota in channel catfish (Ictalurus punctatus)
Researchers exposed channel catfish to nanoplastics and bisphenol A, both alone and combined, and found the combination caused more severe liver and intestinal damage than either substance alone. The co-exposure also disrupted gut bacteria in ways that amplified toxicity. Since nanoplastics and BPA commonly co-exist in polluted water, their combined effects on aquatic organisms may be worse than what single-pollutant studies suggest.
Combined toxic effects of polystyrene microplastic and benzophenone-4 on the bioaccumulation, feeding, growth, and reproduction of Daphnia magna
Researchers examined the combined toxic effects of polystyrene microplastics and the UV filter chemical benzophenone-4 on water fleas over 21 days. They found that exposure to both contaminants together caused greater harm to feeding, growth, and reproduction than either pollutant alone. The study demonstrates that microplastics and personal care product chemicals can interact to amplify their negative effects on freshwater organisms.
Combined toxic effects of polyethylene microplastics and lambda-cyhalothrin on gut of zebrafish (Danio rerio)
Researchers found that polyethylene microplastics can adsorb the pesticide lambda-cyhalothrin from water and then release it in the guts of zebrafish, worsening its toxic effects. Fish exposed to both microplastics and the pesticide showed greater oxidative stress, immune disruption, and gut microbiome changes than those exposed to the pesticide alone. This demonstrates how microplastics can act as carriers that amplify the toxicity of other environmental pollutants in aquatic organisms consumed by humans.
Multi‐Biomarkers' Responses in Gills of Oreochromis niloticus Exposed to Glyphosate and Polyethylene Microplastic, Isolated and in Mixture
Researchers exposed tilapia fish to polyethylene microplastics and the herbicide glyphosate, both alone and in combination, and examined gill tissue for signs of damage. They found that the mixture of both contaminants caused more severe oxidative stress and tissue damage than either pollutant alone. The study suggests that microplastics and agricultural chemicals may interact in waterways to amplify harmful effects on fish health.
Joint effects of micro-sized polystyrene and chlorpyrifos on zebrafish based on multiple endpoints and gut microbial effects
Researchers found that micro-sized polystyrene particles accumulated in zebrafish gut and liver, causing oxidative stress and gut microbiome disruption, and that co-exposure with chlorpyrifos pesticide amplified toxic effects at the individual level.
Additive effects of microplastics on accumulation and toxicity of cadmium in male zebrafish
Researchers exposed adult zebrafish to polyethylene microplastics and cadmium, both individually and in combination, for 21 days. They found that microplastics and cadmium together produced additive toxic effects, increasing cadmium accumulation in fish tissues, altering behavior, and causing more severe organ damage. The study suggests that microplastics in contaminated waterways may worsen the harmful effects of heavy metals on aquatic life.
Co-exposure to polystyrene microplastics and cypermethrin enhanced the effects on hepatic phospholipid metabolism and gut microbes in adult zebrafish
When zebrafish were exposed to both polystyrene microplastics and the pesticide cypermethrin together, the combination caused significantly more liver damage than either pollutant alone. The mixture disrupted fat metabolism in the liver and altered gut bacteria in ways not seen with individual exposures. This matters because microplastics and pesticides frequently co-exist in waterways, and their combined effects on fish health could affect the safety of fish as food.
Combined effects of co-exposure to microcystin-LR and polystyrene microplastics on growth, brain pathology and thyroid hormone homeostasis in adult zebrafish
Researchers exposed zebrafish to microcystin-LR (a toxin from algal blooms) combined with polystyrene microplastics and found that the combination caused significantly worse brain damage and thyroid hormone disruption than either pollutant alone. The microplastics appeared to overwhelm the fish's ability to compensate for the algal toxin, leading to hormone imbalances that could affect growth and development. This is concerning because algal blooms and microplastics frequently occur together in polluted waterways, and their combined effects on the hormone system may be worse than expected.
Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss)
Researchers exposed rainbow trout to polystyrene microplastics combined with the pesticide chlorpyrifos and found that the combination significantly reduced key nutritional parameters (protein, lipid, and moisture content) in muscle tissue compared to either contaminant alone.
Individual and Combined Toxic Effects of Nano-ZnO and Polyethylene Microplastics on Mosquito Fish (Gambusia holbrooki)
Researchers studied the individual and combined effects of polyethylene microplastics and zinc oxide nanoparticles on mosquito fish. The combination caused greater damage to liver tissue, blood parameters, and antioxidant systems than either pollutant alone. The findings suggest that microplastics interacting with other environmental contaminants can amplify toxic effects in aquatic organisms.
Synergetic effects of polyethylene microplastic and abamectin pesticides on the eyes of zebrafish larvae and adults through activation of apoptosis signaling pathways
Researchers exposed zebrafish to polyethylene microplastics and the pesticide abamectin, both individually and in combination, and found that the mixture caused significantly worse eye damage and lower survival rates than either pollutant alone. The combined exposure triggered higher levels of oxidative stress and activated cell death pathways in eye tissues. The study reveals that microplastics and pesticides can interact to produce amplified toxic effects on aquatic organisms, particularly affecting their vision.
The Role of Synthetic Polymers in the Aquatic Environment and Its Implications in Danio Rerio as a Model Organism
Exposing zebrafish to polystyrene microplastics combined with silver nanoparticles caused significantly more oxidative damage, tissue injury in gills and intestines, and higher mortality than either contaminant alone. The study demonstrates that microplastics can act as carriers that enhance the toxicity of co-pollutants like silver nanoparticles, a combination effect that is highly relevant to understanding real-world aquatic contamination where multiple pollutants co-occur.
Combined exposure effects: Multilevel impact analysis of cycloxaprid and microplastics on Penaeus vannamei
Researchers conducted a multilevel analysis of the combined effects of cycloxaprid insecticide and microplastics on a non-target organism, finding synergistic toxicity greater than either contaminant alone. The study highlights risks from simultaneous exposure to agrochemicals and plastic pollution in agricultural environments.