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Single and Combined Effects of Microplastics and Cadmium on the Cadmium Accumulation and Biochemical and Immunity of Channa argus

Biological Trace Element Research 2021 38 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count. Score: 50 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.
Shaodan Wang, Shaodan Wang, Chaonan Zhang, Chaonan Zhang, Di Sun, Chaonan Zhang, Chaonan Zhang, Chaonan Zhang, Chaonan Zhang, Chaonan Zhang, Chaonan Zhang, Shaodan Wang, Chaonan Zhang, Chaonan Zhang, Chaonan Zhang, Chaonan Zhang, Zhengkun Pan, Shaodan Wang, Shaodan Wang, Zhenlu Wang, Zhenlu Wang, Zhenlu Wang, Chaonan Zhang, Di Sun, Chaonan Zhang, Chaonan Zhang, Shaolin Xie, Chaonan Zhang, Chaonan Zhang, Chaonan Zhang, Chaonan Zhang, Chaonan Zhang, Chaonan Zhang, Chaonan Zhang, Shaodan Wang, Shaodan Wang, Shaodan Wang, Shaodan Wang, Shaodan Wang, Shaolin Xie, Shaolin Xie, Chaonan Zhang, Di Sun, Chaonan Zhang, Shaolin Xie, Chaonan Zhang, Zhengkun Pan, Shaodan Wang, Shaodan Wang, Di Sun, Chaonan Zhang, Chaonan Zhang, Zhengkun Pan, Chaonan Zhang, Chaonan Zhang, Chaonan Zhang, Di Sun, Shaolin Xie, Shaolin Xie, Di Sun, Chaonan Zhang, Di Sun, Zhenlu Wang, Zhenlu Wang, Shaodan Wang, Shaodan Wang, Shaodan Wang, Zhengkun Pan, Zhengkun Pan, Chaonan Zhang, Di Sun, Di Sun, Shaodan Wang, Shaodan Wang, Shaodan Wang, Chaonan Zhang, Di Sun, Chaonan Zhang, Shaodan Wang, Shaodan Wang, Di Sun, Jixing Zou Di Sun, Shaodan Wang, Jixing Zou Shaolin Xie, Zhengkun Pan, Di Sun, Di Sun, Shaolin Xie, Zhengkun Pan, Chaonan Zhang, Di Sun, Zhengkun Pan, Shaodan Wang, Zhengkun Pan, Guohuan Xu, Shaodan Wang, Shaodan Wang, Jixing Zou Jixing Zou Chaonan Zhang, Chaonan Zhang, Shaolin Xie, Chaonan Zhang, Di Sun, Jixing Zou Di Sun, Di Sun, Guohuan Xu, Shaolin Xie, Guohuan Xu, Shaolin Xie, Jixing Zou Di Sun, Chaonan Zhang, Zhengkun Pan, Jixing Zou Jixing Zou Guohuan Xu, Guohuan Xu, Shaolin Xie, Shaolin Xie, Jixing Zou Di Sun, Di Sun, Di Sun, Shaolin Xie, Shaolin Xie, Di Sun, Di Sun, Di Sun, Jixing Zou Guohuan Xu, Guohuan Xu, Guohuan Xu, Guohuan Xu, Jixing Zou Jixing Zou Jixing Zou Jixing Zou Jixing Zou Jixing Zou Shaodan Wang, Shaodan Wang, Jixing Zou Jixing Zou Jixing Zou Jixing Zou Guohuan Xu, Jixing Zou Guohuan Xu, Jixing Zou Jixing Zou Jixing Zou Shaolin Xie, Jixing Zou Jixing Zou Shaolin Xie, Guohuan Xu, Jixing Zou

Summary

Researchers investigated the single and combined effects of microplastics and cadmium on juvenile snakehead fish, finding that co-exposure caused greater tissue damage, oxidative stress, and immune disruption than either pollutant alone.

Body Systems
Study Type Environmental

Microplastics can accumulate residual drugs and heavy metals in the environment and accumulate through the layers of the food chain, ultimately causing harm to human health. The pollution of microplastics in the freshwater environment is becoming more and more serious, which directly affects the safety of aquatic organisms. This experiment studied the effects of single and composite microplastics and Cd on the tissue damage, antioxidant, and immune response of juvenile Channa argus. Microplastics with different diameters of 80 nm, 0.5 μm (200 μg/L), and Cd (50 μg/L) were used for exposure, and four sampling points were set for 24 h, 48 h, 96 h, and clear 48 h. Under different treatments, a certain degree of gill tissue damage can be found in 96 h. Microplastics and Cd can cause oxidative stress and affect the antioxidant status, and the impact of 0.5-μm microplastics is stronger than that of 80-nm microplastics. There is an antagonistic effect between the two microplastics and Cd during compound exposure, but the activity of CAT shows a synergistic effect. Microplastics and Cd affect the expression of immune-related genes to varying degrees. When exposed together, the expression of HSP70 gene all showed mutual antagonism, while the expression of IL-1β gene was different. The expression of the MT gene can infer the ability of microplastics to accumulate Cd, and microplastics with a small diameter of 80 nm have stronger enrichment capabilities.

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