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61,005 resultsShowing papers similar to Toxic effects of polystyrene microplastics on atrazine in zebrafish: Exogenous toxicity and endogenous mechanism
ClearCo-exposure to polystyrene microplastics and cypermethrin enhanced the effects on hepatic phospholipid metabolism and gut microbes in adult zebrafish
When zebrafish were exposed to both polystyrene microplastics and the pesticide cypermethrin together, the combination caused significantly more liver damage than either pollutant alone. The mixture disrupted fat metabolism in the liver and altered gut bacteria in ways not seen with individual exposures. This matters because microplastics and pesticides frequently co-exist in waterways, and their combined effects on fish health could affect the safety of fish as food.
Combined neurotoxicity of aged microplastics and thiamethoxam in the early developmental stages of zebrafish (Danio rerio)
This study found that aged (weathered) microplastics combined with the insecticide thiamethoxam caused worse neurological damage to zebrafish larvae than either pollutant alone. The combined exposure reduced heart rate and movement, disrupted antioxidant defenses, and altered neurotransmitter levels in ways that were synergistic rather than simply additive. This is relevant to human health because both microplastics and pesticides are common in the environment, and their combined effects may pose greater risks than either one individually.
A realistic combined exposure scenario: effect of microplastics and atrazine on Piaractus mesopotamicus
Scientists studied the combined effects of polyethylene microplastics and the herbicide atrazine on juvenile pacu fish in a realistic exposure scenario. Researchers found that the combination of these contaminants caused tissue damage and biochemical changes, including altered enzyme activity and genetic damage. The study suggests that microplastics and agricultural chemicals together may pose greater risks to freshwater fish than either pollutant alone.
Single and combined effects of polyethylene microplastics and acetochlor on accumulation and intestinal toxicity of zebrafish (Danio rerio)
This study found that polyethylene microplastics significantly increased the toxicity of acetochlor, a common herbicide, in zebrafish. The microplastics boosted the accumulation of the pesticide in fish tissues and worsened intestinal damage including inflammation and disrupted gut barrier function. The findings are important because microplastics and pesticides frequently co-exist in agricultural waterways, and their combination may pose greater risks than either pollutant alone.
The Exploration of Joint Toxicity and Associated Mechanisms of Primary Microplastics and Methamphetamine in Zebrafish Larvae
Researchers studied how microplastics and methamphetamine together affect zebrafish larvae, since both pollutants frequently co-occur in waterways. The study found that polystyrene microplastics were more lethal than PVC types, and when combined with methamphetamine at higher concentrations, the toxic effects on survival, behavior, and intestinal health became significantly worse.
Combined toxic effects of polyethylene microplastics and lambda-cyhalothrin on gut of zebrafish (Danio rerio)
Researchers found that polyethylene microplastics can adsorb the pesticide lambda-cyhalothrin from water and then release it in the guts of zebrafish, worsening its toxic effects. Fish exposed to both microplastics and the pesticide showed greater oxidative stress, immune disruption, and gut microbiome changes than those exposed to the pesticide alone. This demonstrates how microplastics can act as carriers that amplify the toxicity of other environmental pollutants in aquatic organisms consumed by humans.
Synergetic effects of polyethylene microplastic and abamectin pesticides on the eyes of zebrafish larvae and adults through activation of apoptosis signaling pathways
Researchers exposed zebrafish to polyethylene microplastics and the pesticide abamectin, both individually and in combination, and found that the mixture caused significantly worse eye damage and lower survival rates than either pollutant alone. The combined exposure triggered higher levels of oxidative stress and activated cell death pathways in eye tissues. The study reveals that microplastics and pesticides can interact to produce amplified toxic effects on aquatic organisms, particularly affecting their vision.
Combined hepatotoxicity of imidacloprid and microplastics in adult zebrafish: Endpoints at gene transcription
Researchers investigated the combined liver toxicity of the pesticide imidacloprid and polystyrene microplastics in adult zebrafish over 21 days. The combination caused greater changes in gene expression related to fat and sugar metabolism and inflammatory responses than either contaminant alone. The study suggests that even low concentrations of microplastics and pesticides together may produce more severe hepatotoxic effects than individual exposures.
Toxicity of mixture of polyethylene microplastics and Up Grade® pesticide on Oreochromis niloticus juvenile: I. Hemato-biochemical and histopathological alterations
Researchers exposed juvenile Nile tilapia to a pesticide and polyethylene microplastics, both individually and in combination, and measured blood chemistry changes and organ damage over 15 days. The combination treatment caused more severe effects than either pollutant alone, including reduced red blood cell counts, elevated liver enzymes, and significant tissue damage to the gills and intestines. The study demonstrates that microplastics can worsen the toxic effects of agricultural pesticides on commercially important fish species.
Joint effects of micro-sized polystyrene and chlorpyrifos on zebrafish based on multiple endpoints and gut microbial effects
Researchers found that micro-sized polystyrene particles accumulated in zebrafish gut and liver, causing oxidative stress and gut microbiome disruption, and that co-exposure with chlorpyrifos pesticide amplified toxic effects at the individual level.
Combined impacts of organophosphate pesticide and polyamide microplastics on growth, hematology, and immune responses in juvenile striped catfish (Pangasianodon hypophthalmus)
Researchers exposed juvenile striped catfish to both polyamide microplastics and an organophosphate pesticide, finding that the combination caused more severe growth reduction, immune suppression, and organ damage than either pollutant alone — evidence that microplastics and pesticides can act together to amplify harm in freshwater fish.
The Effects of Single and Combined Exposure to Polystyrene Nanoplastics and Copper on the Behavior of Adult Zebrafish
Researchers studied how polystyrene nanoplastics and copper ions affected zebrafish behavior when the fish were exposed to both pollutants simultaneously. The combination was more toxic than either pollutant alone, reducing the concentration needed to kill fish by up to 32%. Since nanoplastics and heavy metals commonly occur together in polluted water, their combined effects on aquatic life could increase the risks associated with consuming contaminated fish.
The combined toxic effects of polystyrene microplastics and different forms of arsenic on the zebrafish embryos (Danio rerio)
Researchers studied how polystyrene microplastics interact with different forms of arsenic and their combined effects on zebrafish embryos. The microplastics absorbed arsenic from the water and altered how the toxic metal accumulated in zebrafish tissues, changing its toxicity profile. The findings suggest that microplastics in the environment can modify how other pollutants affect living organisms, potentially making combined exposures more harmful than expected.
Polystyrene microplastics and cypermethrin exposure interfered the complexity of antibiotic resistance genes and induced metabolic dysfunction in the gut of adult zebrafish
Zebrafish exposed to a combination of polystyrene microplastics and the pesticide cypermethrin showed more severe gut damage than from either pollutant alone, including loss of beneficial gut bacteria, growth of harmful microbes, and increased antibiotic resistance genes. This suggests that microplastics and pesticides together may disrupt gut health more than expected, which is relevant since humans encounter both pollutants through food and water.
Microplastics aggravate the adverse effects of methylmercury than inorganic mercury on zebrafish (Danio rerio)
Researchers exposed zebrafish embryos to polystyrene microplastics combined with two forms of mercury and found that the microplastics significantly increased the accumulation of methylmercury in the fish. The combination of microplastics and methylmercury caused worse developmental abnormalities, delayed hatching, and greater oxidative stress than either pollutant alone. The study suggests that microplastics can act as carriers for toxic metals, amplifying their harmful effects on aquatic organisms.
Polystyrene microplastics exacerbate acetochlor-induced reproductive toxicity and transgenerational effects in zebrafish
This zebrafish study found that polystyrene microplastics made the herbicide acetochlor significantly more toxic to the reproductive system, and the damage was passed down to the next generation. The microplastics acted as carriers for the pesticide, increasing its absorption and worsening hormone disruption and fertility problems. This is concerning because both microplastics and agricultural chemicals are commonly found together in waterways, where their combined effects may be greater than previously understood.
The Role of Synthetic Polymers in the Aquatic Environment and Its Implications in Danio Rerio as a Model Organism
Exposing zebrafish to polystyrene microplastics combined with silver nanoparticles caused significantly more oxidative damage, tissue injury in gills and intestines, and higher mortality than either contaminant alone. The study demonstrates that microplastics can act as carriers that enhance the toxicity of co-pollutants like silver nanoparticles, a combination effect that is highly relevant to understanding real-world aquatic contamination where multiple pollutants co-occur.
Individual and Combined Toxic Effects of Nano-ZnO and Polyethylene Microplastics on Mosquito Fish (Gambusia holbrooki)
Researchers studied the individual and combined effects of polyethylene microplastics and zinc oxide nanoparticles on mosquito fish. The combination caused greater damage to liver tissue, blood parameters, and antioxidant systems than either pollutant alone. The findings suggest that microplastics interacting with other environmental contaminants can amplify toxic effects in aquatic organisms.
Polystyrene nanoplastic and engine oil synergistically intensify toxicity in Nile tilapia, Oreochromis niloticus
This study found that polystyrene nanoplastics and engine oil together caused much worse damage to Nile tilapia fish than either pollutant alone, triggering severe inflammation, blood cell changes, and oxidative stress. The combined exposure overwhelmed the fish's natural defenses and caused significant organ damage. Since tilapia is a widely consumed fish, this research highlights how mixtures of pollutants in waterways could compound health risks for both aquatic life and humans who eat contaminated seafood.
Toxicological effects of microplastics and phenanthrene to zebrafish (Danio rerio)
Researchers exposed zebrafish to polystyrene microplastics, the pollutant phenanthrene, and a combination of both to assess their toxicity over 24 days. They found that co-exposure amplified oxidative stress, suppressed immune gene expression, and significantly disrupted the gut microbiome compared to either contaminant alone. The study suggests that microplastics can worsen the toxic effects of organic pollutants in aquatic organisms by altering how chemicals accumulate and interact in the body.
Combined effects of polystyrene microplastics and cadmium on oxidative stress, apoptosis, and GH/IGF axis in zebrafish early life stages
Researchers exposed zebrafish embryos to polystyrene microplastics and cadmium, both alone and together, and found that the combination caused significantly worse effects than either pollutant individually. Co-exposure amplified oxidative stress, increased cell death in the spine and esophagus, and disrupted growth hormone pathways more severely than single exposures. The findings suggest that microplastics and heavy metals in waterways may interact to create heightened risks for developing fish.
Combined toxicity of microplastics and cadmium on the zebrafish embryos (Danio rerio)
Researchers exposed zebrafish embryos to polystyrene microplastics combined with cadmium to assess their combined toxic effects on aquatic organisms. The study found that co-exposure produced greater negative impacts on survival and heart rate than either pollutant alone, with toxicity increasing in a concentration-dependent manner.
Toxic impacts of polystyrene nanoplastics and PCB77 in blunt snout bream: Evidence from tissue morphology, oxidative stress and intestinal microbiome
Researchers studied the combined toxicity of polystyrene nanoplastics and a persistent organic pollutant (PCB77) in freshwater fish. They found that co-exposure caused worse tissue damage, higher oxidative stress, and greater disruption to gut bacteria than either contaminant alone. The study highlights that microplastics can worsen the harmful effects of other environmental pollutants when organisms are exposed to both simultaneously.
Effects of single and combined exposure of virgin or aged polyethylene microplastics and penthiopyrad on zebrafish (Danio rerio)
This study found that polyethylene microplastics can increase the toxicity of a common fungicide (penthiopyrad) in zebrafish by helping the chemical build up in their bodies. The combination caused more intestinal damage and disrupted gut bacteria than either pollutant alone. This highlights an important concern: microplastics in the environment can act as carriers for pesticides, potentially amplifying their harmful effects on organisms including those in the human food chain.