Papers

61,005 results
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Article Tier 2

Direct Measurement of Microplastics by Carbon Detection via Single Particle ICP-TOFMS in Complex Aqueous Suspensions

Researchers developed a single particle ICP-TOFMS method for directly measuring microplastics in complex aqueous suspensions by detecting carbon, successfully differentiating microplastic carbon from natural particles and dissolved organic carbon in environmental samples.

2023 Environmental Science & Technology 42 citations
Article Tier 2

Characterisation of microplastics and unicellular algae in seawater by targeting carbon via single particle and single cell ICP-MS

Researchers used single particle and single cell ICP-MS to characterize microplastics and microalgae simultaneously in seawater by targeting carbon signals, demonstrating the technique as a rapid and sensitive tool for distinguishing plastic particles from biological material.

2021 Analytica Chimica Acta 62 citations
Article Tier 2

Characterization of a high-sensitivity ICP-TOFMS instrument for microdroplet, nanoparticle, and microplastic analyses

Researchers characterized the capabilities of an ICP time-of-flight mass spectrometry instrument for single-droplet and single-particle analysis, demonstrating its high sensitivity for simultaneously detecting multiple elements in individual microdroplets, nanoparticles, and microplastic particles.

2022 Journal of Analytical Atomic Spectrometry 38 citations
Article Tier 2

Development of microdroplet calibration for the accurate quantification of particles by single-particle ICP-TOFMS

Researchers developed and validated a microdroplet calibration technique for single-particle ICP-TOFMS to improve accuracy and throughput in multi-elemental quantification of nanoparticles and microparticles in complex sample matrices, achieving single-digit attogram detection limits for many elements.

2024
Article Tier 2

Single-Particle ICP-TOFMS with Online Microdroplet Calibration: A Versatile Approach for Accurate Quantification of Nanoparticles, Submicron Particles, and Microplastics in Seawater

Online microdroplet calibration was used with single-particle ICP-TOFMS to overcome matrix effects and achieve accurate multi-element quantification in nanoparticle and microparticle samples, demonstrating a versatile approach for environmental and industrial nanoparticle analysis.

2023 Analytical Chemistry 18 citations
Article Tier 2

Development of single-cell ICP-TOFMS to measure nanoplastics association with human cells

Researchers developed a new single-cell analytical technique using ICP-TOFMS to measure how nanoplastic particles associate with individual human cells. This method enables detection of nanoplastics at the single-cell level, offering a more precise way to study how these tiny plastic particles interact with human tissues. The approach addresses a critical gap in understanding nanoplastic exposure and uptake in biological systems.

2023 Environmental Science Nano 20 citations
Article Tier 2

CO2-based matrix-independent carbon quantification approach for single microplastic-ICP-MS analysis

Researchers developed a CO2-based matrix-independent calibration approach for single particle ICP-MS analysis, enabling accurate size determination of microplastics between 2–7 μm without needing particle-type-specific standards.

2025 Analytical and Bioanalytical Chemistry 2 citations
Article Tier 2

Fundamental studies on droplet throughput and the analysis of single cells using a downward-pointing ICP-time-of-flight mass spectrometer

This study explored the capabilities of a downwardly oriented inductively coupled plasma time-of-flight mass spectrometer (ICP-TOFMS) for analyzing individual droplets and single cells. The time-of-flight configuration enabled rapid multi-element detection within short transient signals, improving single-cell elemental analysis throughput.

2021 Journal of Analytical Atomic Spectrometry 15 citations
Article Tier 2

Analysis of microplastics in consumer products by single particle-inductively coupled plasma mass spectrometry using the carbon-13 isotope

Researchers developed a method using single particle inductively coupled plasma mass spectrometry (SP-ICP-MS) with carbon-13 isotope detection to analyze micro- and nanoplastics in consumer products, demonstrating that this technique can characterize particle size distributions and concentrations in complex matrices previously inaccessible to inorganic nanoparticle methods.

2020 Talanta 102 citations
Article Tier 2

Laser Ablation for Nondestructive Sampling of Microplastics in Single-Particle ICP-Mass Spectrometry

This study characterized laser ablation as a sampling method for introducing microplastic particles into an ICP-mass spectrometer for single-event carbon detection, enabling nondestructive analysis of microplastics of different types and sizes. The approach preserves particle integrity while providing elemental characterization.

2023 Analytical Chemistry 18 citations
Article Tier 2

A new elemental analytical approach for microplastic sum parameter analysis—ETV/ICP-MS with CO2

Researchers developed a novel electrothermal vaporization (ETV) coupled to ICP-MS method for detecting microplastics as a sum parameter using carbon-13 signals, calibrated against carbon dioxide gas. The technique achieved size-independent detection across polymer types with a limit of detection equivalent to a single ~70 µm polyethylene sphere, offering a fast, traceable analytical tool for complex environmental samples.

2025 Analytical and Bioanalytical Chemistry
Article Tier 2

Catching particles by atomic spectrometry: Benefits and limitations of single particle - inductively coupled plasma mass spectrometry

This review evaluates single-particle inductively coupled plasma mass spectrometry (SP-ICP-MS) as an analytical technique, highlighting its expanding capabilities for detecting, sizing, and quantifying metal-based nanoparticles and emerging applications in microplastic and carbon-based particle analysis.

2022 Spectrochimica Acta Part B Atomic Spectroscopy 31 citations
Article Tier 2

Nanoplastic Labelling with Metal Probes: Analytical Strategies for Their Sensitive Detection and Quantification by ICP Mass Spectrometry

Researchers developed metal probe labelling strategies to enable sensitive detection and quantification of nanoplastics by ICP mass spectrometry, overcoming the challenge that nanoplastics are too small and carbon-rich for conventional analytical techniques to distinguish.

2021 Molecules 30 citations
Article Tier 2

Multimethod Platform Based on Dynamic Image Analysis and spICP-MS for Number-Based Quantification of Microplastics

Researchers developed and validated a multimethod analytical platform combining dynamic image analysis and single-particle ICP-MS to reliably quantify the number concentration of small microplastics (1-10 µm), a size range that has been difficult to measure accurately with existing methods.

2025 Analytical Chemistry
Article Tier 2

Extending theLinear Dynamic Range of Single ParticleICP-MS for the Quantification of Microplastics

Researchers extended the linear dynamic range of single-particle ICP-MS for microplastic quantification to enable detection across a wider concentration range with high throughput. The method improvements allow more accurate characterisation of MP particle number and size distributions in environmental and biological samples.

2025 Figshare
Article Tier 2

Living in a transient world: ICP-MS reinvented via time-resolved analysis for monitoring single events

This review describes how time-resolved ICP-MS analysis has transformed the technique from bulk elemental analysis into a tool for characterizing individual nanoparticles and single cells, enabling detection and characterization of nanoplastics and other nano-objects in complex samples.

2022 Chemical Science 79 citations
Article Tier 2

MultimethodPlatform Based on Dynamic Image Analysisand spICP-MS for Number-Based Quantification of Microplastics

Researchers developed and validated a multimethod platform combining dynamic image analysis (DIA) and single-particle ICP-MS (spICP-MS) for reliably quantifying the number concentration of small microplastics (1-10 µm), identifying critical instrument parameters that affect measurement accuracy for each technique.

2025 Figshare
Article Tier 2

Total organic carbon (TOC): a simple tool for assessing micro(nano)plastics and nanocellulose recovery during size-based fractionation.

Researchers evaluated total organic carbon (TOC) measurement as a simple quality control tool for assessing analyte recovery of metal-free micro(nano)plastics and nanocellulose during size-based fractionation, addressing the gap left by ICP-MS methods that are only applicable to metal-containing particles.

2025 Analytical and bioanalytical chemistry
Article Tier 2

Complementary analysis of pristine, UV-aged and extracted microplastics using single particle ICP-MS and OF2i-Raman spectroscopy

Researchers evaluated two emerging techniques for analyzing individual microplastic particles: single particle ICP-MS for measuring carbon mass per particle, and a novel optofluidic force induction Raman spectroscopy method for identifying polymer type. When applied together to study UV degradation of nylon-6 and polyethylene, the techniques provided complementary information linking physical size changes to molecular structural alterations. The study demonstrates how combining these methods can improve detection and characterization of environmentally aged microplastics.

2026 Talanta
Article Tier 2

Investigating the Cellular Uptake of Model Nanoplastics by Single-Cell ICP-MS

Researchers developed gold-doped polyethylene and polyvinyl chloride nanoparticles as model nanoplastics and used single-cell ICP-MS to investigate their cellular uptake. The study demonstrated that this approach enables rapid, high-throughput detection of nanoplastic interactions with cells, providing a valuable tool for understanding how environmentally relevant nanoplastics behave at the cellular level.

2023 Nanomaterials 25 citations
Article Tier 2

Evolution of the proportion of initial Carbon retrieved in Microplastics as a function of post-aging carbonyl index.

This study tracks the evolution of the proportion of initial carbon retrieved in microplastics as a function of the post-aging carbonyl index, providing a quantitative measure of carbon loss during environmental degradation of plastic particles. The findings contribute to understanding how polymer aging affects carbon accounting in microplastic degradation studies.

2025 Figshare
Article Tier 2

Critical evaluation of the potential of ICP-MS-based systems in toxicological studies of metallic nanoparticles

This review evaluates advanced mass spectrometry techniques for studying how metallic nanoparticles behave in biological systems, including how they enter cells, where they accumulate, and how they transform inside the body. While focused on metal nanoparticles rather than microplastics, many of the same analytical methods are being applied to track nanoplastics in tissues. Better tools for detecting and measuring tiny particles in the body are essential for understanding the real health impacts of nanoplastic exposure.

2024 Analytical and Bioanalytical Chemistry 16 citations
Article Tier 2

Improving the Detectability of Microplastics in River Waters by Single Particle Inductively Coupled Plasma Mass Spectrometry

Single particle ICP-MS with an acid pre-treatment step was developed for rapid screening of microplastics in Pyrenean river waters, detecting carbon-containing particles down to 1 micron and at concentrations of 100 particles per mL, with results confirmed by Raman microscopy.

2023 Nanomaterials 25 citations
Article Tier 2

ICP-MS-Based Characterization and Quantification of Nano- and Microstructures

Researchers developed ICP-MS-based methods for characterizing and quantifying both nano- and microstructures in environmental and biological samples, evaluating the capability of single-particle ICP-MS and bulk analysis to distinguish particle populations by size, elemental composition, and number concentration. The methodology demonstrated detection of particles down to the low nanometer size range in complex matrices.

2024 Nanomaterials 4 citations