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Characterization of a high-sensitivity ICP-TOFMS instrument for microdroplet, nanoparticle, and microplastic analyses
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Researchers characterized the capabilities of an ICP time-of-flight mass spectrometry instrument for single-droplet and single-particle analysis, demonstrating its high sensitivity for simultaneously detecting multiple elements in individual microdroplets, nanoparticles, and microplastic particles.
We report the capabilities of an inductively coupled plasma time-of-flight mass spectrometry (ICP-TOFMS) instrument for single-droplet and single-particle analysis.
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Researchers developed and validated a microdroplet calibration technique for single-particle ICP-TOFMS to improve accuracy and throughput in multi-elemental quantification of nanoparticles and microparticles in complex sample matrices, achieving single-digit attogram detection limits for many elements.
Single-Particle ICP-TOFMS with Online Microdroplet Calibration: A Versatile Approach for Accurate Quantification of Nanoparticles, Submicron Particles, and Microplastics in Seawater
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Online microdroplet calibration was used with single-particle ICP-TOFMS to overcome matrix effects and achieve accurate multi-element quantification in nanoparticle and microparticle samples, demonstrating a versatile approach for environmental and industrial nanoparticle analysis.
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This study developed a total consumption microdroplet ICP-TOFMS method to determine carbon content in microplastics and single cells, overcoming size limitations of conventional nebulization methods. The approach enables more accurate elemental characterization of individual microplastic particles.
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Researchers developed a single particle ICP-TOFMS method for directly measuring microplastics in complex aqueous suspensions by detecting carbon, successfully differentiating microplastic carbon from natural particles and dissolved organic carbon in environmental samples.
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This review describes how time-resolved ICP-MS analysis has transformed the technique from bulk elemental analysis into a tool for characterizing individual nanoparticles and single cells, enabling detection and characterization of nanoplastics and other nano-objects in complex samples.
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