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61,005 resultsShowing papers similar to Biological effects of Micro and Nanoplastics from environmentally relevant sources on an in vitro model of the intestinal barrier
ClearHuman exposure to micro- and nanoplastic: biological effects and health consequence
This review summarized the biological effects and health consequences of human exposure to micro- and nanoplastics, covering routes of uptake (ingestion, inhalation, dermal), cellular toxicity mechanisms, and systemic health risks identified in recent experimental and epidemiological studies.
Biological effects of polystyrene micro- and nano-plastics on human intestinal organoid-derived epithelial tissue models without and with M cells.
Researchers exposed human intestinal organoid-derived epithelial tissue models with and without M cells to polystyrene micro- and nano-plastics, finding that nano-plastics caused greater disruption of barrier integrity and uptake than micro-plastics, and that M cell-containing models showed enhanced particle translocation compared to standard epithelial models.
Micro- and nanoplastics: origin, sources of intake and impact on human health (literature review)
This literature review synthesizes mechanisms by which micro- and nanoplastics interact with living organisms, examining their physicochemical properties, routes of human exposure, and documented health effects across multiple organ systems.
Nanoplastics in the Environment: Sources, Fate, Toxicity, Challenges and Mitigation Strategies
This review covers the formation, environmental fate, and health risks of nanoplastics, emphasizing their capacity to penetrate biological barriers and cause oxidative stress, inflammation, DNA damage, and endocrine disruption, alongside current strategies for mitigation.
Micro(nano)plastics and Their Potential Impact on Human Gut Health: A Narrative Review
This review summarizes research on how micro- and nanoplastics affect the gut, finding that they can damage the intestinal lining, trigger immune responses, and disrupt the balance of beneficial gut bacteria in both cell studies and animal models. Since humans are primarily exposed to microplastics through food and food packaging, understanding these gut effects is essential for assessing the true health risks of plastic pollution.
Immunotoxicity and intestinal effects of nano- and microplastics: a review of the literature
This review examines the evidence on how nano- and microplastics affect the immune system and intestinal health. The findings suggest that exposure to these particles can disrupt the gut microbiome and impair critical intestinal barrier functions, potentially contributing to the development of chronic inflammatory and immune conditions.
Untoward Effects of Micro- and Nanoplastics: An Expert Review of Their Biological Impact and Epigenetic Effects
This expert review examined the biological and epigenetic effects of micro- and nanoplastics on living organisms. The study suggests that while intestinal uptake of plastic particles appears relatively low and size-dependent, nanoplastics may dysregulate molecular signaling pathways, alter gut microbiota composition, and induce transgenerational epigenetic changes potentially linked to metabolic disorders.
Micro(nano)plastics in food system: potential health impacts on human intestinal system.
This review assessed how micro(nano)plastics in the human food system reach the intestine and accumulate in the gut, summarizing evidence that they can alter intestinal barrier function, trigger inflammation, and disrupt the gut microbiome, with implications for long-term digestive health.
Uptake and Effects of Micro‐, Submicro‐ and Nanoplastics Investigated on in vitro Models of the Intestinal Barrier and the Liver
Researchers investigated the uptake and toxic effects of micro-, submicro-, and nanoplastics using in vitro models of the intestinal barrier and liver to assess how plastic particles of different sizes interact with gastrointestinal and hepatic cells. The study examined cellular internalization, barrier integrity, and metabolic responses to characterize size-dependent toxicity mechanisms.
Potential effects of MPs and their co-pollutants on human intestinal tract
This review examines how microplastics and their co-pollutants enter and damage the human intestinal tract, summarizing evidence for microplastic-induced gut barrier disruption, microbiota alteration, and systemic translocation to other organs.
Effects of Nanoplastics on Human Health: A Comprehensive Study
This comprehensive review examines the diverse health effects of nanoplastics, drawing on toxicology, environmental science, and epidemiology to document how these particles interact with human biological systems. The authors conclude that nanoplastics represent a growing public health concern requiring further investigation.
Effect of microplastics and nanoplastics in gastrointestinal tract on gut health: A systematic review.
This systematic review of 30 in vitro studies found that microplastics and nanoplastics cause size- and concentration-dependent damage to human gastrointestinal cells, including increased oxidative stress, mitochondrial dysfunction, inflammation, and apoptosis. Smaller particles consistently showed greater cellular uptake and biological effects, though chronic low-dose exposure generally produced minimal impacts.
Effects of microplastics and nanoplastics on marine environment and human health
This review examines the effects of micro- and nanoplastics on marine environments and human health, covering sources, environmental fate, and biological impacts. Researchers summarize evidence that these particles can cause oxidative stress, inflammation, and disruption of gut microbiota in exposed organisms. The study highlights that while the full extent of health risks remains uncertain, the pervasive presence of plastic particles in food, water, and air makes continued research a public health priority.
Micro(nano)plastics and their potential impact on human gut health: a narrative review
This narrative review synthesizes evidence on how microplastics and nanoplastics affect the human gut, discussing ingestion routes, gut barrier interactions, microbiome disruption, and potential systemic health effects.
Evaluation des effets toxiques de micro et nanoparticules de plastique, en co-contamination avec des métaux, sur des modèles intestinaux humains, in vitro
This French-language dissertation evaluated the in vitro toxicity of micro- and nanoplastics co-contaminated with metals on human intestinal models, finding that combined exposures enhanced toxicity and that large specific surface areas of nanoplastics facilitated contaminant co-transport into intestinal cells.
In vitro toxicity study of micro- and nanoplastics, with co-contamination of metals, on human intestinal models
This French-language study used human intestinal cell models to evaluate the in vitro toxicity of micro- and nanoplastics co-contaminated with heavy metals, finding that combined exposure was more toxic than plastic particles alone and that nanoplastics were more harmful than microplastics.
Microplastics and Nanoplastics in the Environment: Sources, Toxicity, and Ecological Implications
This review covered the sources, environmental fate, toxicological effects, and ecological risks of microplastics and nanoplastics across all environmental compartments. The authors emphasized the bioaccumulation potential, persistence, and toxic effects of MNPs and called for coordinated international efforts to address this global contamination challenge.
Micro(nano)plastics, an emerging health problem
This review frames micro- and nanoplastics as an emerging human health problem, synthesizing evidence of exposure routes, organ-level accumulation, and biological effects, and calling for updated regulatory frameworks to address this novel class of environmental contaminants.
Potential adverse health effects of ingested micro- and nanoplastics on humans. Lessons learned from in vivo and in vitro mammalian models
This review compiles recent studies on the effects of ingested micro- and nanoplastics using mammalian in vivo and in vitro models to assess potential human health implications. The authors found that while substantial research effort has been made, significant gaps remain in understanding absorption, biodistribution, and toxicity of these particles in mammalian systems. The review provides recommendations for improved testing methods to generate more relevant and targeted data for human risk assessment.
Potential Health Impact of Environmentally Released Micro- and Nanoplastics in the Human Food Production Chain: Experiences from Nanotoxicology
This review assesses the potential for micro- and nanoplastics to enter the human food chain, drawing on evidence from studies of food production and related biological systems. Researchers found that while larger microplastics are unlikely to be absorbed by the human body, nanoplastics may be small enough to cross biological barriers and accumulate in tissues. The study highlights that much remains unknown about real-world human exposure levels and calls for more research into the health implications of these tiny particles in food.
Potential risk assessment and toxicological impacts of nano/micro-plastics on human health through food products
This review examined the potential risks and toxicological effects of nano- and microplastics on human health through food products, identifying key contamination sources in the food chain and their harmful impacts on the body.
Micro- and Nanoplastics in the Environment: Current State of Research, Sources of Origin, Health Risks, and Regulations—A Comprehensive Review
This review summarizes the current state of research on micro- and nanoplastics found in air, water, and soil worldwide. These tiny plastic particles pose significant threats to human health including oxidative stress, inflammation, cellular damage, and possible cancer-causing effects, and the authors call for stronger regulations and more research into how they harm the body.
Micro and nano-plastics, a threat to human health?
This review examines the threat micro- and nanoplastics pose to human health, discussing how these persistent particles accumulate in organs including lungs, the gastrointestinal system, and blood, and how their chemical composition and size influence toxicity.
Nanoplastics - A Potential Threat To Human Health?
This thesis examined the inflammatory properties of nanoplastics in the context of both nanomedicine development and understanding health risks from nanomaterial waste. It evaluated whether nanoplastics could trigger immune responses in human cells, which is a key concern given increasing exposure through food and air.