Papers

61,005 results
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Article Tier 2

Scalable Biosynthesis & Recovery of Poly-3-Hydroxybutyrate Produced from Cotton-Derived Glucose by Ralstonia eutropha

Researchers optimised the biosynthesis and recovery of poly-3-hydroxybutyrate using cotton-derived glucose as a substrate with Ralstonia eutropha, addressing the high production costs that limit large-scale use of this biodegradable biopolymer alternative to petroleum-based plastics.

2025 Preprints.org
Article Tier 2

A Review on Enhancing Cupriavidus necator Fermentation for Poly(3-hydroxybutyrate) (PHB) Production From Low-Cost Carbon Sources

This review summarizes strategies for enhancing poly(3-hydroxybutyrate) bioplastic production by Cupriavidus necator using low-cost carbon sources, covering metabolic engineering approaches and fermentation optimization as sustainable alternatives to conventional plastics.

2022 Frontiers in Bioengineering and Biotechnology 88 citations
Article Tier 2

Biosynthesis of Poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) from CO2 by a Recombinant Cupriavidusnecator

A recombinant Cupriavidus necator strain was engineered to produce the flexible, marine-biodegradable copolyester PHBHHx from CO2 as the sole carbon source, demonstrating a route to bio-based plastic production that avoids competition with food crops for feedstocks.

2021 Bioengineering 50 citations
Article Tier 2

Characterization of Poly(3-hydroxybutyrate) (P3HB) from Alternative, Scalable (Waste) Feedstocks

This study compares two biodegradable bioplastics (P3HB) made from waste feedstocks — one produced by cyanobacteria using sunlight and CO2, the other by methane-eating bacteria — and finds both have thermal and mechanical properties on par with conventionally produced P3HB. The relevance to microplastics is indirect: switching to genuinely biodegradable plastics made from waste gases could reduce the long-lasting microplastic particles generated by conventional petroleum-based polymers.

2023 Bioengineering 12 citations
Article Tier 2

Selection of polyhydroxybutyrate-producing bacteria and their polyhydroxybutyrate production using cassava and glycerol as carbon sources

Researchers selected effective polyhydroxybutyrate (PHB)-producing bacteria and evaluated their ability to produce PHB using low-cost carbon sources including cassava and glycerol, aiming to reduce the high production costs that limit PHB bioplastics as a competitive alternative to synthetic plastics.

2025 Agriculture and Natural Resources
Article Tier 2

Statistical optimization of P(3HB-co-3HHx) copolymers production by Cupriavidus necator PHB−4/pBBR_CnPro-phaCRp and its properties characterization

This paper is not about microplastics; it describes optimization of bacterial fermentation conditions to produce a biodegradable bioplastic copolymer (P(3HB-co-3HHx)) using palm oil as a carbon source.

2023 Scientific Reports 12 citations
Article Tier 2

A review on poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) [P(3HB-co-3HHx)] and genetic modifications that affect its production

This review examined the properties, biodegradation behavior, and application potential of the biopolymer P(3HB-co-3HHx), a polyhydroxyalkanoate with mechanical properties comparable to common commodity plastics. The authors assess its viability as a drop-in replacement for single-use plastics, medical devices, and packaging with genuine end-of-life biodegradability.

2022 Frontiers in Bioengineering and Biotechnology 54 citations
Article Tier 2

Enhanced production of biobased, biodegradable, Poly(3-hydroxybutyrate) using an unexplored marine bacterium Pseudohalocynthiibacter aestuariivivens, isolated from highly polluted coastal environment

Researchers isolated and characterised Pseudohalocynthiibacter aestuariivivens P96, a marine bacterium from a highly polluted coastal environment, finding it capable of producing poly(3-hydroxybutyrate) (PHB) at up to 4.73 g/L corresponding to 87% of total cell dry weight, representing a promising bio-based and biodegradable alternative to fossil-fuel plastics.

2022 Bioresource Technology 18 citations
Article Tier 2

Production of Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) by Haloferax mediterranei Using Candy Industry Waste as Raw Materials

Researchers explored using candy industry waste as a low-cost feedstock for the haloarchaeon Haloferax mediterranei to produce PHBV, a biodegradable polymer that could serve as an alternative to conventional plastics. They found that the microorganism could effectively convert sugar-rich waste streams into this bio-based material without requiring expensive precursor chemicals. The study presents a circular economy approach that simultaneously addresses food industry waste and plastic pollution.

2024 Bioengineering 17 citations
Article Tier 2

Disruption of poly (3-hydroxyalkanoate) depolymerase gene and overexpression of three poly (3-hydroxybutyrate) biosynthetic genes improve poly (3-hydroxybutyrate) production from nitrogen rich medium by Rhodobacter sphaeroides

Bacterial genes were engineered to improve production of PHB, a natural biodegradable plastic substitute, in bacteria that grow without using sugar as a carbon source. More efficient bio-based plastic production could help reduce dependence on petroleum-derived plastics.

2019 Microbial Cell Factories 40 citations
Article Tier 2

Leptolyngbya sp. NIVA-CYA 255, a Promising Candidate for Poly(3-hydroxybutyrate) Production under Mixotrophic Deficiency Conditions

Researchers investigated the cyanobacterium Leptolyngbya sp. NIVA-CYA 255 as a candidate for biodegradable poly(3-hydroxybutyrate) (PHB) bioplastic production, finding that a three-stage cultivation process combining phototrophic nitrogen/phosphorus depletion followed by mixotrophic sodium acetate supplementation enhanced PHB accumulation, confirmed by FTIR, GC-MS, and fluorescent dye analyses.

2022 Biomolecules 15 citations
Article Tier 2

Sustainable Cotton Gin Waste/Polycaprolactone Bio-Plastic with Adjustable Biodegradation Rate: Scale-Up Production through Compression Moulding

This paper is not directly about microplastics; it explores the development of a biodegradable composite bioplastic made from cotton gin waste and polycaprolactone, aimed at reducing conventional plastic waste through compostable alternatives.

2023 Polymers 11 citations
Article Tier 2

Influence of microbial biomass content on biodegradation and mechanical properties of poly(3-hydroxybutyrate) composites

This paper is not about microplastics — it studies how adding microbial biomass (algae and cyanobacteria) to a biodegradable polyester (PHB) accelerates its degradation rate in soil.

2023 Biodegradation 10 citations
Article Tier 2

Polyhydroxyalkanoate production by Cupriavidus necator with inedible rice

Researchers optimized polyhydroxyalkanoate (PHA) production by Cupriavidus necator using inedible rice hydrolysate as a carbon source, achieving 4.82 g/L PHA at 68.6% cell content after 72 hours at 5-L scale, comparable to glucose-fed conditions (4.74 g/L at 77.6%). The study demonstrates that inedible rice hydrolysate is a viable low-cost feedstock for biodegradable PHA polymer production as an alternative to petroleum-based plastics.

2022 BioResources 15 citations
Article Tier 2

Isolation, Production, Extraction, Optimization and Fortification of PHB using Silver Nanoparticles from Lactobacillus Casei

Researchers isolated soil bacteria capable of producing the biopolymer polyhydroxybutyrate (PHB) as a biodegradable plastic substitute, optimizing PHB production from Lactobacillus casei and exploring fortification with silver nanoparticles to enhance material properties.

2025
Article Tier 2

Fast, inexpensive, and reliable HPLC method to determine monomer fractions in poly(3-hydroxybutyrate-co-3-hydroxyvalerate)

Researchers developed a fast, inexpensive HPLC method for accurately determining monomer fractions in poly(3-hydroxybutyrate-co-3-hydroxyvalerate), a biodegradable microbial plastic copolymer. The method provides a reliable alternative to existing techniques for supporting bioprocess control and mathematical modeling in bioplastic production.

2021 Applied Microbiology and Biotechnology 26 citations
Article Tier 2

Enhancing the Mechanical Properties of Inherently Brittle, Biobased and Biodegradable Polyhydroxybutyrate (PHB) Polymer by Cotton Fibre Reinforcement and Interfacial Grafting

This study developed biobased and biodegradable packaging films by modifying PLA and PBSA blends, achieving improved flexibility and toughness compared to brittle pure PLA, with the goal of replacing fossil-fuel-based packaging materials with compostable alternatives.

2025 Advanced Sustainable Systems 2 citations
Article Tier 2

Characterization of newly isolated thermotolerant bacterium Cupriavidus sp. CB15 from composting and its ability to produce polyhydroxyalkanoate from glycerol

Researchers characterized a newly isolated thermotolerant bacterium, Cupriavidus sp. CB15, from composting environments and demonstrated its ability to produce polyhydroxyalkanoate (PHA) bioplastic from glycerol, offering a cost-effective route to biodegradable polymer production.

2023 Microbial Cell Factories 12 citations
Article Tier 2

Sugar Beet Molasses as a Potential C-Substrate for PHA Production by Cupriavidus necator

Sugar beet molasses hydrolysates were evaluated as low-cost carbon substrates for polyhydroxyalkanoate (PHA) bioplastic production by the bacterium Cupriavidus necator, finding that the strain could efficiently convert molasses sugars into PHA at competitive yields. The study supports agricultural byproduct streams as economically viable feedstocks for scaling up microbially produced biodegradable plastics.

2022 Bioengineering 41 citations
Article Tier 2

Microbial Production of Biopolymer Polyhydroxybutyrate (PHB): Current Challenges and its Application

This review examines the microbial production of polyhydroxybutyrate (PHB), a biodegradable polyester produced by microorganisms as an energy and carbon storage compound, covering current production challenges and industrial applications. The study discusses PHB as a biopolymer alternative to petroleum-based plastics, addressing cost, yield, and scalability barriers limiting its commercial adoption.

2023 Asian Journal of Chemistry 3 citations
Article Tier 2

Physicochemical cell disruption of Bacillus sp. for recovery of polyhydroxyalkanoates: future bioplastic for sustainability

Researchers tested mechanical methods — including grinding, sonication, and glass bead vortexing — to extract polyhydroxybutyrate (PHB), a biodegradable plastic produced by bacteria, without using toxic chemical solvents. Sonication with a lysis buffer achieved the highest yield at 45%, pointing toward greener industrial processes for producing this promising sustainable bioplastic.

2024 3 Biotech 10 citations
Article Tier 2

A Review of PHB Production by Cyanobacteria and Its Applications

This review examines cyanobacteria as photoautotrophic producers of polyhydroxybutyrate (PHB) bioplastic, summarizing how nutrient-stress conditions stimulate PHB accumulation and evaluating the cost-effectiveness and sustainability of using cyanobacteria as an alternative to conventional feedstocks for biodegradable plastic production.

2022 Journal Of Biochemical Technology 8 citations
Article Tier 2

Copolymers and Blends Based on 3-Hydroxybutyrate and 3-Hydroxyvalerate Units

This paper is not about microplastics. It reviews the biodegradable biopolymer PHBV (poly(3-hydroxybutyrate-co-3-hydroxyvalerate)), covering its production, properties, degradation behavior, and applications in various sectors. While PHBV is studied as a potential biodegradable alternative to conventional plastics, this paper focuses on polymer science and materials engineering rather than microplastic pollution.

2023 International Journal of Molecular Sciences 27 citations
Article Tier 2

A bibliometric landscape of polyhydroxyalkanoates production from low-cost substrates by Cupriavidus necator and its perspectives for the Latin American bioeconomy

This bibliometric analysis examined research on polyhydroxyalkanoate (PHA) biopolymer production by the model bacterium Cupriavidus necator using low-cost substrates, reviewing the field's relevance to the Latin American bioeconomy. Cupriavidus necator can accumulate PHAs up to 90% of dry cell weight, making it a key organism for developing biodegradable alternatives to petroleum-based plastics.

2024 Journal of Applied Biology & Biotechnology 5 citations