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61,005 resultsShowing papers similar to Cellular and Systemic Impacts of Microplastics and Nanoplastics
ClearCellular and Systemic Impacts of Microplastics and Nanoplastics
This review systematically examined the cellular and systemic health impacts of micro- and nanoplastics, covering uptake mechanisms, organ distribution, and effects on inflammation, oxidative stress, and endocrine function. The authors conclude that MNPs pose credible risks to multiple body systems and call for stronger regulatory action.
Cellular Impact of Micro(nano)plastics on Human Health: A Review.
This review examined how micro(nano)plastics (MNPs) entering the human body through ingestion, inhalation, and skin contact affect cells and tissues. It synthesized evidence of oxidative stress, inflammation, DNA damage, and endocrine disruption associated with MNP exposure.
Cellular and Systemic Effects of Micro- and Nanoplastics in Mammals—What We Know So Far
This review summarized known cellular and systemic effects of micro- and nanoplastics in mammals, finding that while ingestion is common, knowledge of health impacts remains limited, with oxidative stress and inflammation as the most reported biological responses.
The potential impacts of micro-and-nano plastics on various organ systems in humans
This review summarizes research on how micro- and nanoplastics can affect virtually every organ system in the human body, including the digestive, respiratory, immune, and reproductive systems. The evidence from animal and cell studies shows these particles cause harm through oxidative stress, inflammation, immune dysfunction, and disrupted metabolism, though more research using realistic exposure levels in humans is needed.
Microplastics and Nanoplastics in Health Concerning Cellular Toxicity Mechanisms, Exposure Pathways, and Global Mitigation Strategies
This review synthesizes current knowledge on how micro- and nanoplastics cause cellular damage in the human body, covering mechanisms like oxidative stress, inflammation, DNA damage, and disruption of cell signaling pathways. Researchers note that exposure occurs through multiple routes including ingestion and inhalation, allowing particles to reach organs throughout the body. The study highlights significant gaps in understanding long-term and low-dose exposure effects that are most relevant to everyday human contact with these particles.
Effects of micro-and-nano plastics on various organ systems in health
This review examines the toxicological effects of micro- and nanoplastics on multiple human organ systems—including the gut, liver, lungs, cardiovascular system, and brain—summarizing mechanisms of harm such as oxidative stress, inflammation, and endocrine disruption.
Molecular and Cellular Effects of Microplastics and Nanoplastics in the Pathogenesis of Cardiovascular, Nervous, Urinary, Digestive, and Reproductive System Diseases: A Global Systematic Review
This systematic review examines how micro- and nanoplastics cause damage at the cellular level across multiple body systems, including the heart, brain, kidneys, gut, and reproductive organs. The key mechanisms include oxidative stress, inflammation, and disruption of protective barriers in the body, suggesting that ongoing plastic exposure may contribute to a wide range of health problems.
Recent consequences of micro-nanaoplastics (MNPLs) in subcellular/molecular environmental pollution toxicity on human and animals
This review examines the subcellular and molecular mechanisms by which micro- and nanoplastics cause toxicity in humans and animals, focusing on oxidative stress, inflammation, cell death pathways, and endocrine disruption at the cellular level.
Cellular and Molecular Mechanisms of Micro- and Nanoplastics Driving Adverse Human Health Effects
This review examines the biological mechanisms by which micro- and nanoplastics may cause harm in humans, including oxidative stress, inflammation, disruption of protective barriers, and immune system problems. Evidence from lab and animal studies suggests these particles can affect the gut, heart, brain, and reproductive systems, though human data is still limited to detecting plastics in tissues rather than proving they cause specific diseases. The authors highlight that most studies use higher doses than people actually encounter, making it important to develop research models that better reflect real-world chronic exposure.
Micro and Nanoplastics on Human Health and Diseases: Perspectives and Recent Advances
This review covers how micro- and nanoplastic particles enter the human body through ingestion, inhalation, infusion, and skin absorption, distribute to virtually all tissues and organs via the circulatory system, and cause health impacts including inflammatory responses, cellular damage, and endocrine disruption.
Research progress on the cellular toxicity caused by microplastics and nanoplastics
This review summarizes current research on how microplastics and nanoplastics cause damage at the cellular level. Researchers identified four main ways these particles harm cells: triggering oxidative stress, damaging cell membranes and organelles, causing inflammation, and disrupting DNA. The findings highlight growing evidence that plastic particles small enough to enter cells can interfere with fundamental biological processes.
Microplastics and Nanoplastics in Human Health: Toxicological Mechanisms Involving Oxidative Stress, Endocrine Interference, and Inflammatory Responses
Tiny plastic particles called microplastics and nanoplastics are now found everywhere—in our air, water, and food—and this review of existing research shows they may harm our health in three main ways. These particles can damage cells, disrupt hormones, and cause inflammation throughout the body, potentially affecting organs like the heart, liver, and brain. While scientists are still studying exactly how dangerous these plastic particles are to humans, the evidence suggests we should be concerned about our constant exposure to them.
Effect of Nanoplastics on Different Biological Systems
This review examines how nanoplastics affect multiple biological systems — including digestive, reproductive, nervous, and immune systems — synthesizing evidence that nanoplastics cross biological barriers and cause oxidative stress, inflammation, and physiological dysfunction across species.
Recent insights into uptake, toxicity, and molecular targets of microplastics and nanoplastics relevant to human health impacts
This review summarizes what scientists know about how tiny plastic particles enter the human body and cause harm at the cellular level, including through inflammation, oxidative stress, and disruption of important cell signaling pathways. Americans are estimated to consume tens of thousands to millions of micro- and nanoplastic particles per year, and these particles can penetrate cells and tissues throughout the body.
Micro- and Nanoplastics on Human Health and Diseases: Perspectives and Recent Advances
This review provides a comprehensive overview of how micro- and nanoplastics enter the human body through ingestion, inhalation, and skin absorption, and how they can then travel through the bloodstream to reach virtually every organ. Researchers summarize evidence that these particles can trigger inflammation, oxidative stress, and disruption of hormonal and immune functions. The study emphasizes that the ability of these particles to cross biological barriers and accumulate in tissues makes understanding their long-term health effects an urgent research priority.
Human exposure to micro- and nanoplastic: biological effects and health consequence
This review summarized the biological effects and health consequences of human exposure to micro- and nanoplastics, covering routes of uptake (ingestion, inhalation, dermal), cellular toxicity mechanisms, and systemic health risks identified in recent experimental and epidemiological studies.
Exposure Pathways, Systemic Distribution, and Health Implications of Micro- and Nanoplastics in Humans
This review summarizes how micro- and nanoplastics enter the human body through food, air, and skin, then distribute to organs throughout the body. Research in animal and cell models shows these particles can cause oxidative stress, inflammation, brain toxicity, reproductive problems, and potentially cancer, though standardized methods for assessing real-world human health risks are still needed.
Micro-and Nanoplastic-Induced Biochemical Toxicity: Emerging Mechanisms and Health Risks Across Biological Systems
This comprehensive review synthesizes current understanding of how micro- and nanoplastics cause biochemical toxicity across biological systems, from plants and invertebrates to vertebrates and humans. Key mechanisms include oxidative stress, membrane disruption, immune activation, genotoxicity, endocrine disruption, and microbiome perturbation, all modulated by particle size, shape, and surface chemistry. The authors highlight critical gaps in standardization, chronic low-dose effect data, and the need for translatable biomarkers for risk assessment.
Micro/nanoplastics and human health: A review of the evidence, consequences, and toxicity assessment
This review summarizes evidence that micro and nanoplastics have been found in multiple human organs and body fluids, where they can alter cell shape, damage mitochondria, reduce cell survival, and cause oxidative stress. The health effects depend heavily on the size, shape, and chemical makeup of the particles, with smaller nanoplastics generally posing the greatest risk because they penetrate deeper into tissues. The review provides a framework for assessing how dangerous different types of plastic particles are to human health.
Micro- and nanoplastic induced cellular toxicity in mammals: A review
This review examines research on how micro- and nanoplastics cause cellular damage in mammalian systems, covering both laboratory and animal studies. Evidence indicates that these particles can trigger oxidative stress, inflammation, and DNA damage in cells, with smaller nanoplastics generally showing greater toxicity due to their ability to penetrate cell membranes more readily.
Exploring toxicological pathways of microplastics and nanoplastics: Insights from animal and cellular models
This review examines what animal and cell studies have revealed about how microplastics and nanoplastics cause harm at the molecular level, including promoting inflammation, oxidative stress, and cell death. Most research has focused on reproductive toxicity and polystyrene particles, while effects on the gut, brain, and heart remain understudied. The authors note that many experiments use unrealistic concentrations and synthetic particles, making it difficult to apply the results to real-world human exposure.
Evidence from in vitro and in vivo studies on the potential health repercussions of micro- and nanoplastics
This review synthesizes evidence from in vitro and in vivo studies on the potential health effects of micro- and nanoplastics. Researchers found that studies have documented plastic particle absorption by cells, immune responses, and effects on multiple organ systems, though the study notes that more research is needed to fully characterize the health implications for humans.
Micro(nano)plastics: an Emerging Burden for Human Health
This review summarizes recent research on how micro- and nanoplastics affect human health, noting that these particles have been found accumulating in the cardiovascular, nervous, reproductive, and digestive systems. The evidence points to oxidative stress and inflammation as key mechanisms of harm, with recent human studies now providing direct evidence of cardiovascular toxic effects from plastic particle exposure.
Adverse Outcome Phenomena and Toxicity Mechanisms of Micro and Nanoplastics in Human Health
This review examines the growing evidence that micro- and nanoplastics can enter the human body through food, water, and air, and may contribute to harmful biological effects. Researchers found that these tiny particles can trigger oxidative stress, inflammation, and disruption of hormonal and immune systems in laboratory studies. The study highlights the need for a unified research approach to better understand how microplastic exposure may affect long-term human health.