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20 resultsShowing papers similar to Health impacts of micro- and nanoplastics: key influencing factors, limitations, and future perspectives
ClearRecent advances in toxicological research of nanoplastics in the environment: A review
Researchers systematically reviewed nanoplastic toxicology, finding that surface charge and particle size are the dominant determinants of harm — positively charged and smaller particles penetrate cell membranes more readily — and that adsorbed contaminants released inside organisms often pose greater toxicological risks than the nanoplastic particles themselves.
Micro- and nanoplastics: origin, sources of intake and impact on human health (literature review)
This literature review synthesizes mechanisms by which micro- and nanoplastics interact with living organisms, examining their physicochemical properties, routes of human exposure, and documented health effects across multiple organ systems.
Comparative Analysis of the Toxicity of Micro‐ and Nanoplastics along with Nanoparticles on the Ecosystem
This comparative review analyzes the toxicity of micro- and nanoplastics across biological systems, examining how particle size, shape, surface chemistry, and polymer type influence toxic potency. The authors synthesize findings from in vitro, in vivo, and ecological studies to support comparative risk assessment.
Micro-and Nanoplastic-Induced Biochemical Toxicity: Emerging Mechanisms and Health Risks Across Biological Systems
This comprehensive review synthesizes current understanding of how micro- and nanoplastics cause biochemical toxicity across biological systems, from plants and invertebrates to vertebrates and humans. Key mechanisms include oxidative stress, membrane disruption, immune activation, genotoxicity, endocrine disruption, and microbiome perturbation, all modulated by particle size, shape, and surface chemistry. The authors highlight critical gaps in standardization, chronic low-dose effect data, and the need for translatable biomarkers for risk assessment.
Effects of Nanoplastics on Human Health: A Comprehensive Study
This comprehensive review examines the diverse health effects of nanoplastics, drawing on toxicology, environmental science, and epidemiology to document how these particles interact with human biological systems. The authors conclude that nanoplastics represent a growing public health concern requiring further investigation.
Characterization, occurrence, environmental behaviors, and risks of nanoplastics in the aquatic environment: Current status and future perspectives
This review characterized the occurrence, environmental behavior, and toxicity of nanoplastics in aquatic systems, noting that their small size gives them unique properties — including higher surface reactivity and greater bioavailability — that make them potentially more hazardous than larger microplastics, while also harder to detect.
Micro and nano-plastics, a threat to human health?
This review examines the threat micro- and nanoplastics pose to human health, discussing how these persistent particles accumulate in organs including lungs, the gastrointestinal system, and blood, and how their chemical composition and size influence toxicity.
Properties and Related Effects of Microplastics in the Aquatic Environment: From the Organismic to Cellular Level
This review covers the properties of microplastics in aquatic environments — including polymer chemistry, particle size, shape, and surface charge — and how these characteristics determine their biological effects from the cellular to organismal level in aquatic organisms.
A critical viewpoint on current issues, limitations, and future research needs on micro- and nanoplastic studies: From the detection to the toxicological assessment.
This critical review examines the current methods for detecting and characterizing micro- and nanoplastics in various environmental samples, as well as reported toxic effects from in vivo and in vitro studies. The authors found that while substantial effort has been made to understand microplastic behavior, the scientific community is still far from a complete understanding of how these particles behave in biological systems. The review calls for improved standardized protocols and more studies focused on uptake kinetics, accumulation, and biodistribution.
Multiple Effects, Pathways, and Potential Health Risks from Environmental Microplastic Exposure
This review synthesizes nearly two decades of research on the multiple pathways through which environmental microplastics affect human and ecological health, including chemical toxicity, physical impacts, and potential roles as carriers of pathogens and contaminants.
Human exposure to micro- and nanoplastic: biological effects and health consequence
This review summarized the biological effects and health consequences of human exposure to micro- and nanoplastics, covering routes of uptake (ingestion, inhalation, dermal), cellular toxicity mechanisms, and systemic health risks identified in recent experimental and epidemiological studies.
Nanoplastic toxicity towards freshwater organisms
This systematic review covers nanoplastic toxicity toward freshwater organisms, examining both conventional and bioplastic nanoplastics, and finds that size, shape, and surface chemistry all influence toxicity across a range of invertebrate and vertebrate freshwater species.
Nanoplastics in the Environment: Sources, Fate, Toxicity, Challenges and Mitigation Strategies
This review covers the formation, environmental fate, and health risks of nanoplastics, emphasizing their capacity to penetrate biological barriers and cause oxidative stress, inflammation, DNA damage, and endocrine disruption, alongside current strategies for mitigation.
Toxicological considerations of nano-sized plastics
This review examined the toxicological considerations specific to nanoplastics, focusing on how particle deposition in different biological compartments, physical properties (size, shape, surface chemistry), and chemical additives interact to determine biological effects. The authors argue that understanding nanoplastic toxicology requires shifting focus from exposure characterization to mechanistic biological relevance at the tissue and organ level.
The Immunotoxic Effects of Environmentally Relevant Micro- and Nanoplastics
Researchers characterized the immunotoxic effects of over 20 types of micro- and nanoplastic particles on macrophages and dendritic cells, finding that physicochemical properties such as size, shape, polymer type, and surface oxidation strongly influence immune cell responses.
Micro/nanoplastics and human health: A review of the evidence, consequences, and toxicity assessment
This review summarizes evidence that micro and nanoplastics have been found in multiple human organs and body fluids, where they can alter cell shape, damage mitochondria, reduce cell survival, and cause oxidative stress. The health effects depend heavily on the size, shape, and chemical makeup of the particles, with smaller nanoplastics generally posing the greatest risk because they penetrate deeper into tissues. The review provides a framework for assessing how dangerous different types of plastic particles are to human health.
Key mechanisms of micro- and nanoplastic (MNP) toxicity across taxonomic groups
This review examines the key ways micro- and nanoplastics cause biological harm across different types of organisms, from bacteria to humans. Researchers identified several common toxicity mechanisms including cell membrane damage, reactive oxygen species generation, DNA damage, and disruption of cellular structures like lysosomes and mitochondria. The study found that toxicity depends heavily on particle size, surface characteristics, and polymer type, and that human cell studies provide especially valuable insights into potential health risks.
Microplastic toxicity: mechanisms, assessment methods, and future research directions
This review synthesizes current knowledge on microplastic toxicity mechanisms, integrating physical, chemical, and biological pathways into a unified framework. Researchers examined assessment methods across aquatic organisms, terrestrial species, and human cell models, identifying critical knowledge gaps and recommending standardized approaches for future microplastic toxicity research.
Micro- and nanoplastic toxicity on aquatic life: Determining factors
This comprehensive review examined the key factors that determine the toxicity of micro- and nanoplastics to aquatic organisms. Researchers found that harmful effects depend on particle concentration, size, exposure time, shape, polymer type, and the species being exposed. The most commonly reported impacts included disrupted growth, oxidative stress, inflammation, immune system changes, and altered metabolism, with smaller particles generally causing more severe effects.
Nanoplastics impact on marine biota: A review
Researchers reviewed the emerging toxicological literature on nanoplastics in marine ecosystems, distinguishing primary nanoplastics (manufactured at nanoscale) from secondary nanoplastics (fragmented from larger debris), and summarizing how nanoscale size changes particle reactivity and bioavailability in ways that differ substantially from their macro- and microscale counterparts.