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61,005 resultsShowing papers similar to Rutin Protects Liver and Kidneys against the Toxicity of Plastic Compounds in Rats
ClearNarirutin ameliorates polystyrene microplastics induced nephrotoxicity by modulating oxidative stress, inflammation and Nrf2/Keap1 pathway
Researchers investigated whether narirutin, a natural compound found in citrus fruits, could protect kidneys from damage caused by polystyrene microplastics in rats. The study suggests that microplastic exposure triggered significant kidney stress through oxidation and inflammation, but narirutin helped reduce that damage by activating protective cellular pathways.
Ameliorative Effects of Rhamnetin against Polystyrene Microplastics-Induced Nephrotoxicity in Rats
Researchers investigated whether the flavonoid rhamnetin could protect against kidney damage caused by polystyrene microplastics in rats. The study found that microplastic exposure significantly increased oxidative stress and inflammatory markers while reducing antioxidant enzyme activity, but co-treatment with rhamnetin restored kidney parameters and mitigated the damage.
Protective effects of herbacetin against polystyrene microplastics-instigated liver damage in rats
Researchers investigated the protective effects of herbacetin, a natural flavonoid, against liver damage caused by polystyrene microplastic exposure in rats. The study found that herbacetin helped restore antioxidant enzyme levels and reduce inflammation markers, suggesting it may offer some protection against microplastic-associated oxidative stress in liver tissue.
Evaluation of Possible Ameliorative Role of Robinetin to Counteract Polystyrene Microplastics Instigated Renal Toxicity in Rats
Researchers tested whether robinetin, a plant-derived compound, could protect rat kidneys from damage caused by polystyrene microplastic exposure. They found that microplastics caused significant kidney harm through oxidative stress, inflammation, and cell death, but robinetin supplementation substantially reversed these effects. The study suggests that natural antioxidant compounds may offer a protective strategy against microplastic-related organ damage.
Attenuative effects of tamarixetin against polystyrene microplastics‐induced hepatotoxicity in rats by regulation of Nrf‐2/Keap‐1 pathway
Researchers investigated whether tamarixetin, a naturally occurring flavonoid, could reduce liver damage caused by polystyrene microplastic exposure in rats. The study found that tamarixetin helped protect against microplastic-induced liver toxicity by activating antioxidant defense pathways, suggesting potential protective effects of certain plant-derived compounds against microplastic-related oxidative stress.
Attenuative Effects of Ginkgetin Against Polystyrene Microplastics-Induced Renal Toxicity in Rats
Researchers found that ginkgetin, a natural flavonoid, significantly reduced polystyrene microplastic-induced kidney damage in rats by restoring antioxidant enzyme activity and reducing oxidative stress and inflammation markers.
Protective Effect of Resveratrol on Kidney Disease and Hypertension Against Microplastics Exposure in Male Juvenile Rats
Researchers investigated whether resveratrol, a natural plant compound, could protect young rats from kidney damage and high blood pressure caused by microplastic exposure. They found that microplastics elevated blood pressure and creatinine levels through oxidative stress, and that resveratrol treatment effectively prevented these effects. The study suggests resveratrol may offer protective benefits against organ damage linked to microplastic exposure, partly by improving gut microbiota balance.
Attenuative effects of poncirin against polyethylene microplastics-prompted hepatotoxicity in rats
Researchers tested whether poncirin, a natural plant compound, could protect rat livers from damage caused by polyethylene microplastics. They found that microplastic exposure caused significant oxidative stress, inflammation, and liver tissue damage, which poncirin was able to substantially reduce by activating protective antioxidant pathways. The study suggests that natural compounds like poncirin may help counteract some of the harmful effects of microplastic exposure on the liver.
Sakuranetin counteracts polyethylene microplastics induced nephrotoxic effects via modulation of Nrf2/Keap1 pathway
Researchers found that polyethylene microplastics caused kidney damage in rats by increasing oxidative stress and disrupting a key protective cellular pathway. However, when the natural plant compound sakuranetin was administered alongside the microplastics, it significantly reduced the kidney damage by restoring antioxidant defenses. The study suggests that certain natural compounds may help counteract some of the harmful effects of microplastic exposure on organ health.
Juglanin cures polyethylene microplastics-induced testicular damage in rats
Researchers administered juglanin to rats exposed to polyethylene microplastics and found that the natural flavonoid compound protected against microplastic-induced testicular damage by reducing oxidative stress and inflammation.
Palliative potential of robinetin to avert polystyrene microplastics instigated pulmonary toxicity in rats
Researchers investigated whether the flavonoid compound robinetin could protect against lung damage caused by polystyrene microplastic exposure in rats. They found that robinetin supplementation reduced oxidative stress markers and inflammatory responses in lung tissue that had been damaged by microplastic ingestion. The study suggests that certain natural compounds may help mitigate some of the harmful effects of microplastic exposure on respiratory tissues.
Toxic effect of polyethylene microplastic on testicles and ameliorative effect of luteolin in adult rats: Environmental challenge
Researchers found that polyethylene microplastics caused significant testicular toxicity in adult rats including reduced sperm quality and testosterone levels, while luteolin treatment ameliorated these effects through its antioxidant and anti-inflammatory properties.
Resveratrol Butyrate Esters Reduce Hypertension in a Juvenile Rat Model of Chronic Kidney Disease Exacerbated by Microplastics
Researchers found that resveratrol butyrate esters reduced high blood pressure in young rats that had both chronic kidney disease and microplastic exposure. The protective effects worked by improving nitric oxide levels, regulating the body's blood pressure control system, and positively shifting gut bacteria composition. The study suggests that certain natural compounds may help counteract the cardiovascular harm associated with microplastic exposure.
Pharmacological assessment of delphinidin in counteracting polystyrene microplastic induced renal dysfunction in rats
Researchers investigated whether the plant compound delphinidin could protect against kidney damage caused by polystyrene microplastics in rats. They found that microplastic exposure triggered oxidative stress, inflammation, and cell death markers in kidney tissue, while delphinidin treatment significantly restored normal kidney function. The study suggests that delphinidin may have protective properties against microplastic-induced organ damage in animal models.
Renal and Hepatotoxic Effects of Polyethylene Terephthalate Microplastics in Chronically Exposed Albino Rats
Researchers exposed albino rats to different doses of PET microplastics for 90 days and measured kidney and liver function markers. They found that chronic exposure led to significant changes in serum urea, creatinine, and liver enzymes, suggesting potential kidney and liver damage at higher doses. The study also found that water stored in PET containers exposed to sunlight showed similar toxic effects, raising concerns about everyday plastic container use.
Impact of polyethylene microplastics exposure on kallikrein-3 levels, steroidal-thyroidal hormones, and antioxidant status in murine model: protective potentials of naringin
When male rats were exposed to polyethylene microplastics (the most common type found in packaging), they showed disrupted testosterone, thyroid hormones, and antioxidant defenses. A citrus compound called naringin partially reversed these harmful effects, suggesting both that microplastics can interfere with the hormonal system and that certain natural compounds might offer some protection.
Evaluation of possible attenuative role of chrysoeriol against polyethylene microplastics instigated testicular damage: A biochemical, spermatogenic and histological study
Researchers investigated whether the plant compound chrysoeriol could protect against testicular damage caused by polyethylene microplastics in a rat model. The study found that microplastic exposure reduced antioxidant enzyme activity and increased inflammation markers, while co-administration of chrysoeriol showed a protective effect by mitigating oxidative stress and preserving sperm quality.
Kidney and Liver Disorders Due to Microplastic Exposure: Chronic in Vivo Study in Male White Rats
Male white rats were chronically exposed to microplastics (particles 5 mm or smaller) to assess kidney and liver toxicity, with exposure resulting from environmental weathering and ultraviolet irradiation of plastic materials. The study found measurable histopathological and biochemical damage in both organs, confirming that long-term microplastic exposure causes organ-level injury in mammals.
Correction by "Quertin" of the oxidative-antioxidant system of rats at xenobiotics exposure
This study tested whether the antioxidant flavonoid quercetin could protect rats from oxidative damage caused by xenobiotic (foreign chemical) exposure, finding that quercetin administration reduced biomarkers of oxidative stress and liver damage. The results suggest that natural antioxidants may help counteract some biochemical effects of environmental chemical exposures.
Hepatoprotective effects of astragalin against polystyrene microplastics induced hepatic damage in male albino rats by modulating Nrf-2/Keap-1 pathway
Researchers investigated whether astragalin, a natural plant compound, could protect against liver damage caused by polystyrene microplastics in rats. They found that microplastic exposure triggered oxidative stress and inflammation in the liver, but astragalin treatment restored antioxidant enzyme activity and reduced damage. The study suggests that natural compounds may help counteract some of the harmful effects microplastics have on liver health.
Role of nutraceutical against exposure to pesticide residues: power of bioactive compounds
This review explores how nutraceuticals, which are health-promoting compounds found in foods like fruits, vegetables, and spices, might help protect the body against damage from pesticide exposure. The bioactive compounds, including antioxidants and polyphenols, can support detoxification and repair cellular damage caused by environmental toxins. While focused on pesticides, this approach is relevant to microplastic exposure because microplastics carry pesticides and other chemicals into the body, and dietary interventions could potentially help mitigate some of their harmful effects.
Molecular Mechanisms of Phthalate-Induced Hepatic Injury and Amelioration by Plant-Based Principles
This review examines how phthalates, chemicals commonly added to plastics to make them flexible, damage the liver through oxidative stress, inflammation, and disruption of normal cell signaling. People are exposed to phthalates through air, water, food, and skin contact, and the liver bears the greatest burden as the primary organ for processing these chemicals. The findings are directly relevant to microplastics because phthalates can leach from plastic particles inside the body, making microplastic exposure a potential delivery route for these liver-damaging chemicals.
Cardioprotective potential of sakuranetin to counteract polyethylene microplastics induced cardiotoxicity
The flavonoid sakuranetin protected rat hearts from polyethylene microplastic-induced cardiotoxicity by activating the Nrf2/Keap1 antioxidant pathway, restoring cardiac biomarker levels and reducing oxidative damage caused by 30 days of microplastic exposure.
The Protective Effect of Pumpkin Extract on Polyvinylchloride) PVC( Hepatotoxicity in Male Albino Rats
This study investigated whether pumpkin extract could protect against liver damage caused by polyvinyl chloride (PVC) microplastics in male albino rats, given that PVC is a common and persistent source of microplastic exposure. Results suggested that pumpkin extract offered a protective effect against PVC-induced hepatotoxicity.