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Resveratrol Butyrate Esters Reduce Hypertension in a Juvenile Rat Model of Chronic Kidney Disease Exacerbated by Microplastics

Nutrients 2024 5 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count. Score: 55 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.

Chien‐Ning Hsu You‐Lin Tain, You‐Lin Tain, Yining Huang, You‐Lin Tain, Chien‐Ning Hsu Chih‐Yao Hou, Chien‐Ning Hsu Chih‐Yao Hou, Chih‐Yao Hou, Shin‐Yu Chen, Chih‐Yao Hou, You‐Lin Tain, You‐Lin Tain, You‐Lin Tain, Chien‐Ning Hsu You‐Lin Tain, You‐Lin Tain, You‐Lin Tain, Chien‐Ning Hsu Chih‐Yao Hou, Chien‐Ning Hsu You‐Lin Tain, Chien‐Ning Hsu

Summary

Researchers found that resveratrol butyrate esters reduced high blood pressure in young rats that had both chronic kidney disease and microplastic exposure. The protective effects worked by improving nitric oxide levels, regulating the body's blood pressure control system, and positively shifting gut bacteria composition. The study suggests that certain natural compounds may help counteract the cardiovascular harm associated with microplastic exposure.

Body Systems

Renal

Models

Rat

In conclusion, in this juvenile rat model of combined CKD and MP exposure, RBE demonstrates antihypertensive effects by modulating NO levels, the RAS, gut microbiota, and their metabolites.

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