Papers

61,005 results
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Article Tier 2

Development of microdroplet calibration for the accurate quantification of particles by single-particle ICP-TOFMS

Researchers developed and validated a microdroplet calibration technique for single-particle ICP-TOFMS to improve accuracy and throughput in multi-elemental quantification of nanoparticles and microparticles in complex sample matrices, achieving single-digit attogram detection limits for many elements.

2024
Article Tier 2

Characterization of a high-sensitivity ICP-TOFMS instrument for microdroplet, nanoparticle, and microplastic analyses

Researchers characterized the capabilities of an ICP time-of-flight mass spectrometry instrument for single-droplet and single-particle analysis, demonstrating its high sensitivity for simultaneously detecting multiple elements in individual microdroplets, nanoparticles, and microplastic particles.

2022 Journal of Analytical Atomic Spectrometry 38 citations
Article Tier 2

Application of Single-Particle ICP-MS to Determine the Mass Distribution and Number Concentrations of Environmental Nanoparticles and Colloids

Researchers applied single-particle ICP-MS to characterize elemental composition and size distributions of nanoparticles, colloids, and their aggregates in environmental samples. The study demonstrates that spICP-MS can effectively analyze homoaggregation and heteroaggregation of natural and anthropogenic nanoparticles including plastic-associated metal contaminants.

2021 Environmental Science & Technology Letters 34 citations
Article Tier 2

Extending theLinear Dynamic Range of Single ParticleICP-MS for the Quantification of Microplastics

Researchers extended the linear dynamic range of single-particle ICP-MS for microplastic quantification to enable detection across a wider concentration range with high throughput. The method improvements allow more accurate characterisation of MP particle number and size distributions in environmental and biological samples.

2025 Figshare
Article Tier 2

Direct Measurement of Microplastics by Carbon Detection via Single Particle ICP-TOFMS in Complex Aqueous Suspensions

Researchers developed a single particle ICP-TOFMS method for directly measuring microplastics in complex aqueous suspensions by detecting carbon, successfully differentiating microplastic carbon from natural particles and dissolved organic carbon in environmental samples.

2023 Environmental Science & Technology 42 citations
Article Tier 2

ICP-MS-Based Characterization and Quantification of Nano- and Microstructures

Researchers developed ICP-MS-based methods for characterizing and quantifying both nano- and microstructures in environmental and biological samples, evaluating the capability of single-particle ICP-MS and bulk analysis to distinguish particle populations by size, elemental composition, and number concentration. The methodology demonstrated detection of particles down to the low nanometer size range in complex matrices.

2024 Nanomaterials 4 citations
Article Tier 2

MultimethodPlatform Based on Dynamic Image Analysisand spICP-MS for Number-Based Quantification of Microplastics

Researchers developed and validated a multimethod platform combining dynamic image analysis (DIA) and single-particle ICP-MS (spICP-MS) for reliably quantifying the number concentration of small microplastics (1-10 µm), identifying critical instrument parameters that affect measurement accuracy for each technique.

2025 Figshare
Article Tier 2

Coupling single particle ICP-MS with field-flow fractionation for characterizing metal nanoparticles contained in nanoplastic colloids

A combination of field-flow fractionation and single-particle ICP-MS was used to characterize composite particles containing metal nanoparticles in a polymer matrix, simulating what happens when plastic particles age in the environment and accumulate metals. This analytical approach helps reveal the complex chemical nature of weathered microplastics.

2019 Environmental Science Nano 43 citations
Article Tier 2

Counting Nanoplastics in Environmental Waters by Single Particle Inductively Coupled Plasma Mass Spectroscopy after Cloud-Point Extraction and In Situ Labeling of Gold Nanoparticles

Researchers developed a cloud-point extraction and in-situ gold nanoparticle labeling method combined with single particle ICP-MS to count nanoplastics down to 50 nm in environmental water samples, enabling quantification of nanoplastics previously undetectable by conventional methods.

2021 Environmental Science & Technology 84 citations
Article Tier 2

Multimethod Platform Based on Dynamic Image Analysis and spICP-MS for Number-Based Quantification of Microplastics

Researchers developed and validated a multimethod analytical platform combining dynamic image analysis and single-particle ICP-MS to reliably quantify the number concentration of small microplastics (1-10 µm), a size range that has been difficult to measure accurately with existing methods.

2025 Analytical Chemistry
Article Tier 2

A Novel Strategy for the Detection and Quantification of Nanoplastics by Single Particle Inductively Coupled Plasma Mass Spectrometry (ICP-MS)

A new analytical method was developed to detect and count individual nanoplastic particles in drinking water and river water using gold nanoparticles as tags and single particle ICP-MS for detection. The method can detect nanoplastics as small as 135 nm at environmentally relevant concentrations, providing a sensitive new tool for tracking nanoplastic contamination.

2020 Analytical Chemistry 152 citations
Article Tier 2

Analysis of Ti- and Pb-based particles in the aqueous environment of Melbourne (Australia) via single particle ICP-MS

Researchers used a highly sensitive technique called single particle ICP-MS to detect and characterize titanium dioxide and lead-based nanoparticles across 63 water sampling locations in Melbourne, Australia, mapping their size, concentration, and distribution as a tool for tracking anthropogenic nanomaterial pollution in aquatic environments.

2022 Analytical and Bioanalytical Chemistry 37 citations
Article Tier 2

Characterisation of microplastics and unicellular algae in seawater by targeting carbon via single particle and single cell ICP-MS

Researchers used single particle and single cell ICP-MS to characterize microplastics and microalgae simultaneously in seawater by targeting carbon signals, demonstrating the technique as a rapid and sensitive tool for distinguishing plastic particles from biological material.

2021 Analytica Chimica Acta 62 citations
Article Tier 2

Extending the Linear Dynamic Range of Single Particle ICP-MS for the Quantification of Microplastics

Researchers developed an improved method using single particle inductively coupled plasma mass spectrometry to detect and measure microplastics across a wider size range than previously possible. By extending the linear dynamic range of the technique, they could more accurately size and count larger microplastic particles. The advancement addresses a key limitation in current microplastic analytical methods and could improve environmental monitoring.

2025 Analytical Chemistry 2 citations
Article Tier 2

Determination of carbon in microplastics and single cells by total consumption microdroplet ICP-TOFMS

This study developed a total consumption microdroplet ICP-TOFMS method to determine carbon content in microplastics and single cells, overcoming size limitations of conventional nebulization methods. The approach enables more accurate elemental characterization of individual microplastic particles.

2023 Analytical and Bioanalytical Chemistry 20 citations
Article Tier 2

Improving the Detectability of Microplastics in River Waters by Single Particle Inductively Coupled Plasma Mass Spectrometry

Single particle ICP-MS with an acid pre-treatment step was developed for rapid screening of microplastics in Pyrenean river waters, detecting carbon-containing particles down to 1 micron and at concentrations of 100 particles per mL, with results confirmed by Raman microscopy.

2023 Nanomaterials 25 citations
Article Tier 2

CO2-based matrix-independent carbon quantification approach for single microplastic-ICP-MS analysis

Researchers developed a CO2-based matrix-independent calibration approach for single particle ICP-MS analysis, enabling accurate size determination of microplastics between 2–7 μm without needing particle-type-specific standards.

2025 Analytical and Bioanalytical Chemistry 2 citations
Article Tier 2

Use of metal-tagged environmentally representative micro- and nanoplastic particles to investigate transport and retention through porous media using single particle ICP-MS

Metal-tagged micro- and nanoplastic particles were used with single-particle ICP-MS to study transport and retention of plastic particles through saturated porous media, providing a sensitive method for tracking environmentally representative particles in soil.

2024 Microplastics and Nanoplastics 7 citations
Article Tier 2

Nanoplastics prepared with uniformly distributed metal-tags: a novel approach to quantify size distribution and particle number concentration of polydisperse nanoplastics by single particle ICP-MS

Researchers developed a new method for creating nanoplastic test particles with embedded metal tags, allowing scientists to precisely measure the size and number of nanoplastics using single-particle mass spectrometry. The particles have realistic irregular shapes and varied sizes, unlike the uniform spheres typically used in lab studies. This tool will help researchers more accurately study how nanoplastics behave in environmental and health experiments.

2023 Environmental Science Nano 15 citations
Article Tier 2

Trace element distribution in marine microplastics using laser ablation-ICP-MS

Laser ablation-ICP-MS was applied to characterize trace element distributions within individual microplastic particles collected from marine environments. The technique revealed that microplastics carry and concentrate diverse trace metals on their surfaces, providing direct evidence of their capacity to transport metal contaminants in marine systems.

2020 Marine Pollution Bulletin 48 citations
Systematic Review Tier 1

Determination of metallic nanoparticles in biological samples by single particle ICP-MS: a systematic review from sample collection to analysis

This systematic review found that single particle ICP-MS analysis of engineered nanomaterials in biological samples has focused on only a few nanoparticle compositions, primarily silver and gold, while leaving significant gaps for other materials and important tissue types. The technique enables detection and characterization of individual nanoparticles within complex biological matrices. Similar analytical challenges exist in microplastic research, where detecting and characterizing nano-sized plastic particles in biological tissues remains technically demanding.

2022 Environmental Science Nano 57 citations
Article Tier 2

Two-stage hierarchical clustering for analysis and classification of mineral sunscreen and naturally occurring nanoparticles in river water using single-particle ICP-TOFMS

Single-particle ICP time-of-flight mass spectrometry combined with two-stage hierarchical clustering was used to detect and classify titanium- and zinc-containing nanoparticles from mineral sunscreen against natural particle backgrounds in river water. The method successfully distinguished anthropogenic sunscreen nanoparticles from naturally occurring particles without needing prior knowledge of particle composition.

2024 Environmental Science Nano 8 citations
Article Tier 2

Catching particles by atomic spectrometry: Benefits and limitations of single particle - inductively coupled plasma mass spectrometry

This review evaluates single-particle inductively coupled plasma mass spectrometry (SP-ICP-MS) as an analytical technique, highlighting its expanding capabilities for detecting, sizing, and quantifying metal-based nanoparticles and emerging applications in microplastic and carbon-based particle analysis.

2022 Spectrochimica Acta Part B Atomic Spectroscopy 31 citations
Article Tier 2

Optofluidic Force Induction meets Raman Spectroscopy and Inductively Coupled Plasma – Mass Spectrometry: A new hyphenated technique for comprehensive and complementary characterisations of single particles

Optofluidic force induction was combined with Raman spectroscopy and ICP-MS to characterize nanoparticle size distributions, elemental compositions, and concentrations, demonstrating a multi-modal analytical approach for comprehensive nanoparticle characterization in environmental and industrial contexts.

2023 3 citations