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Systematic Review ? AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button. Tier 1 ? Systematic review or meta-analysis. Synthesizes findings across many studies. Strongest evidence. Nanoplastics Sign in to save

Determination of metallic nanoparticles in biological samples by single particle ICP-MS: a systematic review from sample collection to analysis

Environmental Science Nano 2022 57 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count. Score: 55 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.
Adam Laycock, Nathaniel J. Clark, Nathaniel J. Clark, Nathaniel J. Clark, Nathaniel J. Clark, Richard D. Handy Nathaniel J. Clark, Robert Clough, Nathaniel J. Clark, Nathaniel J. Clark, Robert Clough, Adam Laycock, Nathaniel J. Clark, Nathaniel J. Clark, Nathaniel J. Clark, Nathaniel J. Clark, Nathaniel J. Clark, Robert Clough, Robert Clough, Robert Clough, Rachel Smith, Richard D. Handy Nathaniel J. Clark, Richard D. Handy Richard D. Handy

Summary

This systematic review found that single particle ICP-MS analysis of engineered nanomaterials in biological samples has focused on only a few nanoparticle compositions, primarily silver and gold, while leaving significant gaps for other materials and important tissue types. The technique enables detection and characterization of individual nanoparticles within complex biological matrices. Similar analytical challenges exist in microplastic research, where detecting and characterizing nano-sized plastic particles in biological tissues remains technically demanding.

Study Type Review

A systematic review of the use of single particle ICP-MS to analyse engineered nanomaterials in biological samples has highlighted that efforts have focused on a select few compositions and there is a lack of information for some important tissues.

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