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61,005 resultsShowing papers similar to The Combined Effects of Toxic Microcystis aeruginosa and Thermal Stress on the Edible Clam (Corbicula fluminea): Insights into Oxidative Stress Responses and Molecular Networks
ClearTranscriptome analysis of response mechanism to Microcystin-LR and microplastics stress in Asian clam (Corbicula fluminea)
Researchers used RNA sequencing to analyze gene expression in Asian clam (Corbicula fluminea) hepatopancreas tissue exposed to microcystin-LR, microplastics, and their combination, finding that co-exposure triggered distinct transcriptomic responses compared to individual stressors, with evidence of oxidative and immune pathway disruption.
Evaluation of Microplastics and Microcystin-LR effect for Asian clams (Corbicula flumine) by a metabolomics approach
Using metabolomics, this study found that combined exposure to microplastics and the cyanotoxin microcystin-LR disrupted multiple metabolic pathways in Asian clams, with effects differing from either stressor alone. This matters because freshwater environments often contain both pollutants simultaneously, and the combined metabolic disruption could impair the health of shellfish consumed by humans.
Physiological and transcriptome analysis of Mytilus coruscus in response to Prorocentrum lima and microplastics
The combined effects of diarrhetic shellfish toxin and microplastics on the mussel Mytilus coruscus were assessed at physiological and transcriptomic levels, revealing synergistic disruption of immune function, antioxidant responses, and metabolic pathways. The study provides molecular-level evidence of interactive toxicity between two common coastal contaminants.
Responses of Antioxidant Markers and Valve Activity of the Brackish Water Clam Corbicula Japonica Under Single/combined Exposures of Polystyrene Microplastics and Thermal Stress
Researchers exposed the brackish water clam Corbicula japonica to polystyrene microplastics at 200 μg/L and at two temperatures (20°C and 25°C), finding that thermal stress altered valve activity and antioxidant responses, with warmer temperatures increasing microplastic ingestion and changing oxidative damage patterns.
Evaluation of Microplastics and Microcystin-LR Effect for Asian Clams (Corbicula fluminea) by a Metabolomics Approach
Researchers used a metabolomics approach to investigate the combined effects of microplastics and microcystin-LR on Asian clams, finding that co-exposure caused distinct metabolic responses compared to individual exposures. The study reveals mechanistic interactions between two co-occurring freshwater pollutants at the cellular metabolic level.
Beyond Single Stressors: Integrated Physiological and Transcriptomic Responses of Argopecten irradians Exposed to Polystyrene and Toxic Dinoflagellates
Researchers exposed bay scallops to polystyrene microplastics and toxic algae both individually and in combination, finding that while survival remained above 90%, the combined exposure triggered elevated oxidative stress markers and more complex physiological disruption. Transcriptomic analysis revealed that microplastics primarily interfered with endocrine function while the toxic algae affected immune pathways, and co-exposure produced synergistic effects on metabolism and developmental regulation.
Combining Transcriptomic and Metabolomic Analyses to Investigate the Acute Effects of Microcystin-LR and Nanoplastics of Asian Clams
Researchers combined transcriptomic and metabolomic analyses of river clam hepatopancreas to investigate the individual and combined toxic mechanisms of microcystin-LR and nanoplastics under acute exposure conditions. Integrated analysis of cDNA libraries and metabolites showed significant enrichment of 49, 34, and 44 pathways in microcystin, nanoplastic, and combined treatment groups respectively, revealing distinct and interactive stress response mechanisms.
Multi-Biomarker Responses of Asian Clam Corbicula fluminea (Bivalvia, Corbiculidea) to Cadmium and Microplastics Pollutants
Researchers exposed Asian clams to cadmium, microplastics, and their mixtures, then measured a battery of biomarkers including oxidative stress, energy metabolism, and neurotoxicity indicators. They found that the combined exposure to cadmium and microplastics produced interactive effects that differed from exposure to either contaminant alone. The study demonstrates that microplastics can modify the toxicity of heavy metals in freshwater bivalves, highlighting the importance of studying pollutant mixtures rather than individual contaminants.
Marine mussel metabolism under stress: Dual effects of nanoplastics and coastal hypoxia
This study examined how nanoplastics and low oxygen levels together affect marine mussels, finding that both stressors disrupted the animals' internal balance and energy metabolism. The combination of nanoplastics and oxygen-depleted water was more harmful than either stressor alone, damaging cellular defenses against oxidative stress. Since mussels are widely consumed as seafood, these findings raise questions about the safety of shellfish harvested from polluted, oxygen-poor coastal waters.
Microplastic and Vibrio harveyi co-exposure induces oxidative stress in big-belly seahorse Hippocampus abdominalis
Researchers co-exposed big-belly seahorses to microbeads and Vibrio harveyi bacteria (a common marine pathogen), finding the combination caused greater oxidative stress — measured by superoxide dismutase, catalase, and malondialdehyde levels — than either stressor alone.
Effects of Microplastics Associated with Triclosan on the Oyster Crassostrea brasiliana: An Integrated Biomarker Approach
Brazilian oysters (Crassostrea brasiliana) were exposed to microplastics alone and in combination with the antibacterial chemical triclosan, with combined exposure causing greater oxidative stress, immune disruption, and genotoxicity than either stressor alone.
Interactive Immunomodulation in the Mediterranean Mussel Mytilus galloprovincialis Under Thermal Stress and Cadmium Exposure
Combined exposure to elevated temperature and cadmium in Mediterranean mussels triggered complex interactive effects on immune and antioxidant systems, with simultaneous stressors producing non-additive responses that highlight the difficulty of predicting organism health in multiply polluted warming seas.
Oxidative and metabolic responses in Crassostrea gasar under combined stressors of elevated temperature and microplastic exposure
Researchers exposed oysters (Crassostrea gasar) to polystyrene microplastics at different temperatures to assess their combined effects on oxidative stress and energy metabolism. The study found that both gills and digestive glands accumulated microplastics regardless of temperature, and that the combination of thermal stress and microplastic exposure produced distinct patterns of oxidative stress and metabolic disruption compared to either stressor alone.
Physiological and biochemical responses to caffeine and microplastics in Mytilus galloprovincialis
Researchers exposed Mediterranean mussels to caffeine and microplastics both separately and together to measure their combined effects. The combination caused greater oxidative stress and changes in cell function than either pollutant alone. While focused on mussels, the study is relevant to human health because mussels are widely eaten as seafood and can accumulate both microplastics and chemical contaminants.
iTRAQ-Based Quantitative Proteomic Analysis Reveals Toxicity Mechanisms in Chlamys farreri Exposed to Okadaic Acid
Researchers used iTRAQ-based proteomics to reveal that okadaic acid exposure in scallops (Chlamys farreri) triggers oxidative stress, immune suppression, and disruption of cytoskeletal and energy metabolism pathways, providing mechanistic insights into shellfish toxicity during harmful algal blooms.
Impacts of Microplastics, Cadmium, and Their Mixtures on Biochemical Biomarkers in the Freshwater Bivalve Corbicula fluminea (Bivalvia, Corbiculidea)
This study evaluated the combined impacts of microplastics and cadmium on biochemical biomarkers in a freshwater organism, finding that co-exposure caused greater oxidative stress and cellular damage than either contaminant alone. Microplastics appear to enhance cadmium bioavailability and toxicity.
Responses of Mytilus galloprovincialis in a Multi-Stressor Scenario: Effects of an Invasive Seaweed Exudate and Microplastic Pollution under Ocean Warming
Researchers exposed mussels to a combination of invasive seaweed exudate, polyethylene microplastics, and elevated temperatures to study their combined effects. The study found that simultaneous exposure to all three stressors greatly reduced byssal thread production and depleted antioxidant defenses in gill tissue, suggesting that multiple environmental stressors can amplify harmful effects on marine organisms.
Oxidative Stress in Far Eastern Mussel Mytilus trossulus (Gould, 1850) Exposed to Combined Polystyrene Microspheres (µPSs) and CuO-Nanoparticles (CuO-NPs)
Researchers exposed the marine mussel Mytilus trossulus to polystyrene microspheres and copper oxide nanoparticles alone and in combination for 5 days, finding that both contaminants induced oxidative stress and that combined exposure enhanced lysosomal membrane damage compared to single exposures. The battery of biomarkers including lipid peroxidation, antioxidant activity, and DNA damage provided a sensitive profile of combined toxicity.
Investigation of Toxicity of the Combined Exposure of Microplastics and Arsenic (III) on Clams
This study examined the combined toxicity of microplastics and arsenic(III) on freshwater clams, finding that co-exposure caused greater oxidative stress and tissue damage than either contaminant alone, suggesting synergistic interactions between microplastics and heavy metals.
Exposure to polystyrene nanoplastics and PCB77 induced oxidative stress, histopathological damage and intestinal microbiota disruption in white hard clam Meretrix lyrata
Researchers exposed white hard clams to nanoplastics and a type of industrial pollutant called PCB77, both individually and together, and found that the combination caused more severe damage than either pollutant alone. The clams showed increased oxidative stress, tissue damage in their gills and digestive glands, and significant disruption of their gut bacteria. The findings suggest that nanoplastics may worsen the toxic effects of other environmental contaminants in shellfish.
Does Thermal Stress Modulate the Biochemical and Physiological Responses of Ruditapes Decussatus Exposed to the Progestin Levonorgestrel?
Researchers studied how combined exposure to warming temperatures and the synthetic hormone levonorgestrel (found in contraceptives) affects clams. Both stressors together caused greater disruption to the clam's biochemistry and physiology than either alone. This suggests climate warming may amplify the harm that pharmaceutical pollutants cause to marine shellfish.
Combined effects of polyamide microplastics and the pathogenic bacterium Vibrio parahaemolyticus on the immune parameters of Mytilus coruscus
When mussels were exposed to nylon microplastics along with harmful Vibrio bacteria, they suffered gill damage, increased oxidative stress, and weakened immune defenses compared to either stressor alone. The combined exposure suppressed key immune enzymes that mussels need to fight infection. Since mussels are widely consumed as seafood, this study raises concerns that microplastic-contaminated shellfish could carry more pathogens and be less safe to eat.
Physiological and transcriptomic analyses reveal critical immune responses to hypoxia and sulfide in the haemolymph of clam Tegillarca granosa
This paper is not relevant to microplastics research — it examines how hypoxia and sulfide exposure affect immune responses in blood clams (Tegillarca granosa) at a physiological and transcriptomic level.
The effect of climate change and microplastics on the physiology of marine invertebrates of economic interest
This thesis examines how climate change and microplastic pollution interact to affect the physiology of marine invertebrates important for aquaculture. Combined stressors were found to have compounding effects on organisms like mussels and oysters, threatening both ecosystems and food security.