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61,005 resultsShowing papers similar to Silver nanoparticles in diabetes mellitus: therapeutic potential and mechanistic insights
ClearOral Delivery of Silver Nanoparticles – a Review
This review covers the oral delivery of silver nanoparticles, examining their behavior in the gastrointestinal tract and potential medical applications. The paper is focused on nanoparticle pharmacology rather than environmental microplastics.
An Overview of Nanoparticle Properties and Their Bioactivity
This systematic review summarized the properties and bioactivity of nanoparticles (1-100 nm), covering how their size, shape, and surface characteristics influence their behavior in biological systems and their potential applications in microbiology.
Toxicity of AgNPs upon Liver Function and Positive Role of Tinospora Cordifolia: In Vivo
Researchers found that silver nanoparticle exposure caused significant liver toxicity in male rats, and that Tinospora cordifolia extract provided a protective effect by mitigating the nanoparticle-induced disruption of liver function parameters.
Potential and risks of nanotechnology applications in COVID-19-related strategies for pandemic control
Researchers reviewed the benefits and risks of using nanoparticles in pandemic control strategies, including mRNA vaccine delivery, antiviral face masks coated with metal nanoparticles, and biosensors, noting that while nanoparticles offer powerful new tools, they also carry risks such as immune reactions, hormonal disruption, and environmental contamination from improper disposal. The review calls for careful assessment of these trade-offs as nanotechnology becomes more central to public health responses.
Tissue distribution, placental transfer and excretion of silver nanoparticles in pregnant rats after a single oral dose
Researchers quantitatively tracked silver nanoparticles in organs, fluids, and fetal blood of pregnant rats following a single oral dose, finding placental transfer and time-dependent tissue distribution over 24 hours.
Toward Synthesis-derived Applications of Silver Nanoparticles
This review covers the synthesis methods, antimicrobial properties, and environmental sustainability considerations for silver nanoparticles used in medical and industrial applications. While not directly about microplastics, silver nanoparticles are often embedded in plastics and textiles and are released into water environments as a co-contaminant.
Could Nanotechnology Help to End the Fight Against COVID-19? Review of Current Findings, Challenges and Future Perspectives
This review assessed the potential role of nanotechnology in combating COVID-19, covering nano-enabled diagnostics, drug delivery systems, and vaccines, while noting that most applications were still in early development stages and faced significant regulatory and safety challenges.
Toward Synthesis-derived Applications of Silver Nanoparticles
This review covers the synthesis, properties, and applications of silver nanoparticles, including their antimicrobial uses and environmental risks. While not directly about microplastics, silver nanoparticles are often associated with textile and plastic products and can co-contaminate aquatic environments.
Exploring the micro- and nanoplastics–diabetes nexus: Shattered barriers, toxic links, and methodological horizons
This review examines growing evidence that micro- and nanoplastics may contribute to diabetes by disrupting blood sugar regulation, insulin signaling, and fat metabolism through oxidative stress and inflammation. Animal studies show that plastic particles can damage the pancreas, liver, and gut in ways that mirror the development of diabetes, though human studies are still limited. The review calls for more research into whether everyday microplastic exposure could be a hidden factor in the global rise of metabolic diseases.
Ag- but Not ZnO-Nanoparticles Disturb the Airway Epithelial Barrier at Subtoxic Concentrations
Silver nanoparticles but not zinc oxide nanoparticles were found to disrupt the airway epithelial barrier at subtoxic concentrations in nasal respiratory epithelium cells, suggesting that Ag nanoparticles pose airway barrier integrity risks at exposure levels below cytotoxic thresholds.
Characterization of Nanoparticles in Antimicrobial Coatings for Medical Applications—A Review
This review covers the different types of nanoparticles used in antimicrobial coatings for medical and dental devices, including silver, copper, and zinc-based materials. Researchers discuss the methods used to characterize these coatings and ensure they are effective against drug-resistant microorganisms. The study emphasizes the importance of thorough testing to confirm the safety and performance of these coatings in healthcare settings.
The ancillary effects of nanoparticles and their implications for nanomedicine
Researchers reviewed 'ancillary effects' — the unintended biological interactions between nanoparticles and living systems that occur independent of engineered targeting or therapeutic functions — cataloguing how nanomaterial surface properties can modulate cell signaling, immune responses, and toxicity in ways that have major implications for nanomedicine safety and design.
Biosynthesis and Characterization of Extracellular Silver Nanoparticles from Streptomyces aizuneusis: Antimicrobial, Anti Larval, and Anticancer Activities
Researchers synthesized silver nanoparticles from Streptomyces aizuneusis and demonstrated their antimicrobial, anti-larval, and anticancer activities, contributing to the development of eco-friendly green nanotechnology approaches.
"Nano Packaging and its Potential Application: A Review"
This review examines nano packaging technologies and their potential applications in food preservation and other industries, discussing nanomaterial types, barrier properties, antimicrobial functions, and the regulatory and safety considerations surrounding the use of nanoscale materials in food contact applications.
Targeting Insulin Resistance in Hepatocytes: A Novel Insulin-Mimetic Agent Delivered via an Advanced Nanocarrier System
Researchers developed a Schiff base binuclear vanadium complex delivered via a nanocarrier system and tested its ability to overcome hepatic insulin resistance in cell models of type 2 diabetes. The nanocarrier improved targeted delivery to hepatocytes, reducing toxic side effects while maintaining insulin-mimetic efficacy.
Nanoreinforcement strategies for enhancing biodegradable composites in biochemical applications within agriwaste valorisation
Researchers used leftover plant material from rosemary distillation to synthesize silver nanoparticles with strong antibacterial and antioxidant properties, exploring how agricultural byproducts can produce eco-friendly nanomaterials with potential medical applications including treatment of inflammatory conditions.
Opportunities and Challenges for Nanotherapeutics for the Aging Population
This review explores how nanotherapeutics could address age-related changes in drug pharmacokinetics that impair efficacy and increase toxicity in elderly patients, while noting the need to balance benefits against the long-term safety of nanomaterials.
Assessment of the protective and ameliorative impact of quercetin nanoparticles against neuronal damage induced in the hippocampus by acrolein
Researchers found that quercetin nanoparticles — tiny particles of a natural antioxidant found in plants — protected brain cells in the hippocampus from damage caused by acrolein, a toxic compound linked to Alzheimer's disease, suggesting nanoparticle delivery of quercetin as a potential therapeutic strategy.
Application of Metal Nanoparticles for Production of Self-Sterilizing Coatings
This review examined metal nanoparticles — including silver, gold, copper, and zinc oxide — used in self-sterilizing coatings, summarizing their antimicrobial mechanisms, synthesis methods, and documented activity against pathogenic bacteria, viruses, and fungi for packaging and surface applications.
Safer plant-based nanoparticles for combating antibiotic resistance in bacteria: A comprehensive review on its potential applications, recent advances, and future perspective
This review examines plant-based nanoparticles as safer, less toxic alternatives to conventional antimicrobial agents for combating antibiotic-resistant bacterial infections, highlighting their potential to reduce microbiome damage.
Nanomaterials in Drug Delivery: Strengths and Opportunities in Medicine
This review covers how nanomaterials are being used to improve drug delivery for treating cancer and infections, offering better targeted therapy with fewer side effects. While not directly about microplastics, the research on how nanoparticles interact with human tissues provides insight into how similarly sized nanoplastics might behave once inside the body.
Human health risk assessment of nanoparticles through food consumption — occurrence, exposure, and toxicological implications
This review examined the health risks of nanoparticles found in food and drinking water, analyzing 262 studies from 2016 to 2025. Researchers found that the most commonly reported nanoparticles in food included titanium dioxide, silver, zinc oxide, and micro/nanoplastics, entering through food contact materials, nano-enabled agricultural inputs, and environmental contamination. Evidence consistently pointed to oxidative stress, inflammation, and potential genotoxic effects from dietary nanoparticle exposure.
Brucella species-induced brucellosis: Antimicrobial effects, potential resistance and toxicity of silver and gold nanosized particles
Researchers tested silver and gold nanoparticles against Brucella melitensis and Brucella abortus, finding that silver nanoparticles had stronger antibacterial activity but also induced greater cytotoxicity in host cells. Gold nanoparticles showed lower antibacterial potency but a better safety profile, suggesting they may be more suitable candidates for anti-Brucella nanomedicine development.
Safe Nanoparticles: Are We There Yet?
This review evaluates the current state of nanoparticle safety research across medical, cosmetic, and industrial applications. Researchers found that despite two decades of progress, significant questions remain about the long-term effects of nanoparticle exposure, and the study calls for standardized testing methods and better understanding of how these tiny particles interact with biological systems.