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Could Nanotechnology Help to End the Fight Against COVID-19? Review of Current Findings, Challenges and Future Perspectives

International Journal of Nanomedicine 2021 40 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count. Score: 50 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.

Ashagrachew Tewabe Yayehrad, Ebrahim Abdela Siraj, Gebremariam Birhanu Wondie, Atlaw Abate Alemie, Manaye Tamrie Derseh, Abyou Seyfu Ambaye

Summary

This review assessed the potential role of nanotechnology in combating COVID-19, covering nano-enabled diagnostics, drug delivery systems, and vaccines, while noting that most applications were still in early development stages and faced significant regulatory and safety challenges.

A serious viral infectious disease was introduced to the globe by the end of 2019 that was seen primarily from China, but spread worldwide in a few months to be a pandemic. Since then, accurate prevention, early detection, and effective treatment strategies are not yet outlined. There is no approved drug to counter its worldwide transmission. However, integration of nanostructured delivery systems with the current management strategies has promised a pronounced opportunity to tackle the pandemic. This review addressed the various promising nanotechnology-based approaches for the diagnosis, prevention, and treatment of the pandemic. The pharmaceutical, pharmacoeconomic, and regulatory aspects of these systems with currently achieved or predicted beneficial outcomes, challenges, and future perspectives are also highlighted.

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