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61,005 resultsShowing papers similar to Modulation efficiency of clove oil nano-emulsion against genotoxic, oxidative stress, and histological injuries induced via titanium dioxide nanoparticles in mice
ClearCytotoxicity of Nanoparticles Used in Cosmetic Industries: An In-depth Insight
This review examined the cytotoxicity of nanoparticles used in cosmetic sunscreens, including titanium dioxide and zinc oxide, finding that while these particles provide effective UV protection, their nanoscale form raises concerns about skin penetration and potential cellular toxicity.
Assessment of the protective and ameliorative impact of quercetin nanoparticles against neuronal damage induced in the hippocampus by acrolein
Researchers found that quercetin nanoparticles — tiny particles of a natural antioxidant found in plants — protected brain cells in the hippocampus from damage caused by acrolein, a toxic compound linked to Alzheimer's disease, suggesting nanoparticle delivery of quercetin as a potential therapeutic strategy.
Oral administration of TiO2 nanoparticles during early life impacts cardiac and neurobehavioral performance and metabolite profile in an age- and sex-related manner
Researchers found that feeding titanium dioxide nanoparticles (a common ingredient in food, sunscreen, and paint) to young rats disrupted heart function, brain chemistry, and metabolism in ways that differed by age and sex, with female pups showing greater harm. The findings raise concerns about early-life exposure to nanoparticles that enter the food supply and environment.
Antioxidant Potential of Mangifera foetida Bark, Mangifera foetida Leaves, and Cinnamomum burmanii Leaves Extract in Mitigating Nanoplastic‐Induced Toxicity and Disruption of Glycolipid Metabolism
Researchers tested whether plant extracts from Mangifera foetida and Cinnamomum burmanii could reduce nanoplastic-induced metabolic disruption in rats, finding that the antioxidant compounds in these extracts partially mitigated nanoplastic-associated disruption of glycolipid metabolism.
Protective effects of Vitamin E against Zinc Oxide nanoparticles-induced histotoxicity of liver and testicular tissue, genotoxicity and biomarker stress in male albino rats
This rat study examined whether vitamin E could protect against liver and testicular damage caused by zinc oxide nanoparticles at doses of 50 and 200 mg/kg. Vitamin E at 100 mg/kg provided significant protection against ZnO nanoparticle-induced tissue damage, genotoxicity, and oxidative stress markers.
Titanium (IV) oxide anatase nanoparticles as vectors for diclofenac: assessing the antioxidative responses to single and combined exposures in the aquatic macrophyte Egeria densa
Researchers tested how titanium dioxide nanoparticles — widely used in sunscreens and paints and now common in waterways — affect aquatic plants, both alone and combined with the pain reliever diclofenac, finding that both pollutants triggered stress responses in the water plant Egeria densa. The combination amplified certain enzyme responses, suggesting that these two pollutants together may pose greater environmental risk than either alone.
Human health risk assessment of nanoparticles through food consumption — occurrence, exposure, and toxicological implications
This review examined the health risks of nanoparticles found in food and drinking water, analyzing 262 studies from 2016 to 2025. Researchers found that the most commonly reported nanoparticles in food included titanium dioxide, silver, zinc oxide, and micro/nanoplastics, entering through food contact materials, nano-enabled agricultural inputs, and environmental contamination. Evidence consistently pointed to oxidative stress, inflammation, and potential genotoxic effects from dietary nanoparticle exposure.
Toxic Effect of UV-Pre-Irradiated TiO2 Nanoparticles on the Sand Dollar Scaphechinus mirabilis Sperm
Researchers studied how UV irradiation changes the toxicity of titanium dioxide nanoparticles to sand dollar sperm. The study found that UV pre-treatment altered the properties of the nanoparticles and increased their toxic effects on marine invertebrate reproduction, highlighting how environmental weathering can change the behavior of nanoparticles released into ocean environments.
Quercetin alleviates cyclophosphamide-induced premature ovarian insufficiency in mice by reducing mitochondrial oxidative stress and pyroptosis in granulosa cells
Researchers found that quercetin, a natural plant compound, protected mouse ovaries from chemotherapy-induced damage by reducing harmful oxidative stress in mitochondria and suppressing a form of inflammatory cell death called pyroptosis, suggesting it could help preserve fertility in patients undergoing cancer treatment.
Natural Bioactive Phytocompounds to Reduce Toxicity in Common Carp Cyprinus carpio: A Challenge to Environmental Risk Assessment of Nanomaterials
Researchers investigated the toxic effects of copper oxide nanoparticles on common carp and found that Myristica fragrans seed extract provided protective benefits by reducing oxidative stress and mitigating nanoparticle-induced damage.
Geraniol modulation of oxidative stress caused by polyethylene terephthalate nanoplastics in HEK-293 cell line
Researchers tested whether geraniol, a natural plant compound, could protect human kidney cells (HEK-293) against oxidative stress caused by polyethylene terephthalate nanoplastics, finding that geraniol significantly reduced nanoplastic-induced cellular damage.
Interpreting the potential of biogenic TiO2 nanoparticles on enhancing soybean resilience to salinity via maintaining ion homeostasis and minimizing malondialdehyde
Researchers found that titanium dioxide nanoparticles derived from plants helped soybean crops tolerate salt stress by improving water retention, boosting antioxidant defenses, and keeping beneficial minerals like potassium in balance — offering a potential tool for farming in salt-affected soils.
Protective effect of curcumin against microplastic and nanoplastics toxicity
Researchers reviewed studies examining whether curcumin, the active compound in turmeric, can protect against the toxic effects of micro- and nanoplastics in the body. Evidence indicates that curcumin helped reduce oxidative stress, inflammation, and organ damage caused by plastic particle exposure across multiple organ systems in animal studies. The review suggests that natural antioxidant compounds like curcumin may hold promise for mitigating some of the harmful effects of plastic pollution on health.
Recent Findings in Adverse Effects of Tio2 NPs in Marine Algae and Zooplanktons: A Threat to Marine Ecosystems
This review summarizes recent findings on the harmful effects of titanium dioxide nanoparticles on marine algae and zooplankton. Researchers found that these nanoparticles can cause oxidative stress, DNA damage, and disruptions to cellular processes in marine organisms. The study highlights that TiO2 nanoparticles often interact with other pollutants like microplastics in marine environments, potentially amplifying their combined ecological impact.
Toxicological Effects and Potential Therapeutics of Chronic Exposure to Polyurethane Nanoplastics in Caenorhabditis elegans
Researchers exposed the model organism C. elegans to polyurethane nanoplastics at environmentally relevant concentrations and found dose-dependent toxic effects including reduced reproduction, impaired movement, and shortened lifespan. The study also found that cinnamon essential oil showed potential as a therapeutic agent, enhancing antioxidant defenses and partially mitigating the harmful effects of nanoplastic exposure at lower concentrations.
Synergistic effects of titanium dioxide nanoparticles and microplastics on lentil seeds by a non-invasive biospeckle optical coherence tomography
Scientists tested how tiny titanium dioxide particles (found in sunscreen and food) and microplastics affect lentil seeds using a new imaging technique. They found that smaller particles boosted seed activity at low doses, but when combined with microplastics, the effects changed depending on the mix. This matters because these same particles and microplastics are in our food chain, and understanding how they interact could help us assess potential risks to the crops we eat.
Recent developments in sunscreens based on chromophore compounds and nanoparticles
This review covers recent advances in sunscreen formulations using nanoparticles and light-absorbing compounds. Researchers found that nanoparticles like zinc oxide and titanium dioxide can effectively scatter and absorb UV radiation while remaining cosmetically appealing, and that encapsulating UV-absorbing compounds in nanoparticles can enhance protection. The study also highlights progress toward more photostable, broad-spectrum, and environmentally friendly sunscreen options.
Antioxidant Intervention Against Microplastic Hazards
This review explores how antioxidants like vitamin C, curcumin, and quercetin might protect the body against damage caused by microplastic exposure. Microplastics trigger harmful oxidative stress in cells, and antioxidants can reduce this damage by neutralizing dangerous molecules and activating the body's protective pathways. However, challenges remain because antioxidants are poorly absorbed by the body and their long-term effectiveness against microplastic harm is still unclear.
Protection of Exogenous Antioxidant of Cinnamomum burmanii as a Hepatoprotective on the Toxicological Responses of Nanoplastics in Rats (Rattus norvegicus L.)
Researchers tested whether Cinnamomum burmanni leaf extract (CLE) protects rat liver function from polystyrene nanoplastic toxicity, administering NPs orally for 14 days with or without 100–400 mg/kg CLE for 28 days. NPs caused oxidative stress and liver damage, while CLE at 200–400 mg/kg significantly reduced hepatotoxicity markers and restored antioxidant enzyme activity, suggesting hepatoprotective potential against nanoplastic-induced toxicity.
Correction by "Quertin" of the oxidative-antioxidant system of rats at xenobiotics exposure
This study tested whether the antioxidant flavonoid quercetin could protect rats from oxidative damage caused by xenobiotic (foreign chemical) exposure, finding that quercetin administration reduced biomarkers of oxidative stress and liver damage. The results suggest that natural antioxidants may help counteract some biochemical effects of environmental chemical exposures.
Effectiveness of N-Acetylcysteine on Zinc oxide Nanoparticles-Induced Cardiotoxicity in Adult Albino Rats
Researchers exposed adult albino rats to zinc oxide nanoparticles orally and investigated whether N-acetylcysteine — a free radical scavenger — could protect against ZnO nanoparticle-induced cardiotoxicity, measuring oxidative stress markers, histopathological changes, and cardiac enzyme levels to evaluate the mechanistic basis and protective efficacy of NAC treatment.
Impact of Titanium Dioxide Nanoparticles on Agricultural Crops Performance: A Review of Efficacy and Mechanisms
This paper is not relevant to microplastics research; it reviews the effects of titanium dioxide nanoparticles on agricultural crop performance, focusing on photosynthesis enhancement and antimicrobial protection rather than plastic pollution.
Herbal nanoemulsions in cosmetic science: A comprehensive review of design, preparation, formulation, and characterization
This review provides an overview of herbal nanoemulsion formulations used in cosmetics, covering how they are designed, produced, and characterized for delivering plant-based active ingredients through the skin. Researchers found that nanoemulsion technology improves the solubility and stability of natural compounds while offering better skin penetration than conventional formulations. The study highlights nanoemulsions as a promising, more natural alternative for cosmetic product delivery.
Mitigative potential of kaempferide against polyethylene microplastics induced testicular damage by activating Nrf-2/Keap-1 pathway
Researchers tested whether kaempferide, a natural plant compound with antioxidant properties, could protect against testicular damage caused by polyethylene microplastics in rats. They found that the microplastics triggered significant oxidative stress and tissue damage in the testes, but kaempferide treatment substantially reduced these harmful effects by activating a key protective cellular pathway. The study suggests that natural antioxidant compounds may help counteract some of the reproductive harm associated with microplastic exposure.