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61,005 resultsShowing papers similar to Nanoplastics in the Biological System: A Microscopic Menace with an Impact
ClearToxicity and Accumulation of Nanoplastics Materials: A Review of Experimental Evidence Across Biological Systems
This systematic review of studies from 2010 to 2025 found that nanoplastics can penetrate biological barriers and accumulate in tissues across many organisms. Their tiny size makes them especially concerning because they can enter cells, cause oxidative stress and inflammation, and potentially affect organ function in ways that larger plastic particles cannot.
Human and ecological health effects of nanoplastics: May not be a tiny problem
This review examined the health effects of nanoplastics in humans and ecosystems, finding that while direct human evidence is limited, nanoplastic particles cross biological barriers more readily than larger fragments and trigger oxidative stress, inflammation, and endocrine disruption in animal models, suggesting the problem is far from trivial.
Nanoplastics in the Environment: Sources, Fate, Toxicity, Challenges and Mitigation Strategies
This review covers the formation, environmental fate, and health risks of nanoplastics, emphasizing their capacity to penetrate biological barriers and cause oxidative stress, inflammation, DNA damage, and endocrine disruption, alongside current strategies for mitigation.
Effects of Nanoplastics on Aquatic Organisms
This review summarizes how nanoplastics — plastic particles smaller than 1 micrometer — affect aquatic organisms, highlighting their ability to penetrate cell membranes, accumulate inside organisms, and cause oxidative stress and reproductive harm.
Nanoplastics in Environment
This book chapter provides an overview of nanoplastics in the environment, covering their sources, characterization, identification methods, and ecotoxicological risks. Nanoplastics — below 100 nm in size — are increasingly detected in air, water, soil, and food, raising significant concerns about their potential to cross biological barriers in the human body.
Advances on micro/nanoplastics and their effects on the living organisms: A review
This review examines the current state of research on how micro- and nanoplastics affect plants, animals, microorganisms, and humans. Researchers found that these tiny plastic particles can cause oxidative stress, inflammation, reproductive problems, and disruption of gut microbiomes across a wide range of species. The study highlights that while significant progress has been made in understanding these effects, major gaps remain in assessing long-term exposure risks at realistic environmental concentrations.
Assessing the Impact of Nanoplastics in Biological Systems: Systematic Review of In Vitro Animal Studies
This systematic review of lab studies found that nanoplastics can damage cells in the gut, lungs, liver, brain, and reproductive organs of animals. These ultra-small plastic particles appear capable of crossing biological barriers and causing inflammation and oxidative stress, raising concerns about similar effects in humans.
From natural environment to animal tissues: A review of microplastics(nanoplastics) translocation and hazards studies
This review summarizes how micro- and nanoplastics travel from the environment into animal bodies through water, food, air, and even skin contact, then move through the bloodstream to accumulate in organs. Once inside, these particles cause oxidative stress, inflammation, gut damage, reproductive harm, and nervous system effects across many animal species. The findings strongly suggest that similar pathways of exposure and harm could apply to humans.
Effect of Nanoplastics on Different Biological Systems
This review examines how nanoplastics affect multiple biological systems — including digestive, reproductive, nervous, and immune systems — synthesizing evidence that nanoplastics cross biological barriers and cause oxidative stress, inflammation, and physiological dysfunction across species.
A review on microplastics and nanoplastics in the environment: Their occurrence, exposure routes, toxic studies, and potential effects on human health
This review summarizes what is known about how microplastics and nanoplastics enter the human body through food, air, and skin contact, and what they do once inside. Studies on cells and animals show these tiny particles can cause oxidative stress, DNA damage, inflammation, and harm to the immune, digestive, reproductive, and nervous systems. The research makes clear that microplastics are not just an environmental problem but a direct concern for human health.
Micro- and Nanoplastics in the Environment: Current State of Research, Sources of Origin, Health Risks, and Regulations—A Comprehensive Review
This review summarizes the current state of research on micro- and nanoplastics found in air, water, and soil worldwide. These tiny plastic particles pose significant threats to human health including oxidative stress, inflammation, cellular damage, and possible cancer-causing effects, and the authors call for stronger regulations and more research into how they harm the body.
Micro- and nano-plastics in marine environment: Source, distribution and threats — A review
This review examines the sources, distribution, and threats of micro- and nanoplastics in the marine environment. Researchers found that microplastics are nearly ubiquitous in ocean ecosystems, causing harm to marine animals ranging from malnutrition to chemical poisoning. The study also highlights that nanoplastics can penetrate biological barriers, including the gastrointestinal and blood-brain barriers, and accumulate in vital organs.
Nanoplastics in the Environment
This chapter reviews the emerging concern about nanoplastics — plastic particles smaller than 1 micrometer — which are even harder to detect and may have more pervasive biological effects than larger microplastics. Current analytical challenges make nanoplastics difficult to quantify in the environment, leaving significant knowledge gaps.
Micro- and nanoplastic induced cellular toxicity in mammals: A review
This review examines research on how micro- and nanoplastics cause cellular damage in mammalian systems, covering both laboratory and animal studies. Evidence indicates that these particles can trigger oxidative stress, inflammation, and DNA damage in cells, with smaller nanoplastics generally showing greater toxicity due to their ability to penetrate cell membranes more readily.
Micro-and Nanoplastic-Induced Biochemical Toxicity: Emerging Mechanisms and Health Risks Across Biological Systems
This comprehensive review synthesizes current understanding of how micro- and nanoplastics cause biochemical toxicity across biological systems, from plants and invertebrates to vertebrates and humans. Key mechanisms include oxidative stress, membrane disruption, immune activation, genotoxicity, endocrine disruption, and microbiome perturbation, all modulated by particle size, shape, and surface chemistry. The authors highlight critical gaps in standardization, chronic low-dose effect data, and the need for translatable biomarkers for risk assessment.
Micro/nanoplastics and human health: A review of the evidence, consequences, and toxicity assessment
This review summarizes evidence that micro and nanoplastics have been found in multiple human organs and body fluids, where they can alter cell shape, damage mitochondria, reduce cell survival, and cause oxidative stress. The health effects depend heavily on the size, shape, and chemical makeup of the particles, with smaller nanoplastics generally posing the greatest risk because they penetrate deeper into tissues. The review provides a framework for assessing how dangerous different types of plastic particles are to human health.
The Environmental Impacts of Nanoplastics in Marine Ecosystems
This review examined how nanoplastics—generated by degradation of larger plastics—penetrate biological barriers, accumulate in tissues, contribute to biomagnification, and disrupt marine food chains, highlighting their distinct ecotoxicological mechanisms compared to larger microplastics.
Cellular and Systemic Effects of Micro- and Nanoplastics in Mammals—What We Know So Far
This review summarized known cellular and systemic effects of micro- and nanoplastics in mammals, finding that while ingestion is common, knowledge of health impacts remains limited, with oxidative stress and inflammation as the most reported biological responses.
Impact of Nanoplastics on Marine Life: A Review
This review summarizes current knowledge about the effects of nanoplastics on marine organisms, including impacts on feeding, reproduction, growth, and cellular-level toxicity. Evidence indicates that nanoplastics can be more harmful than larger microplastics due to their ability to cross biological barriers and accumulate in tissues, though more research is needed on real-world exposure levels.
Biological Effects of Microplastics: A Review.
Researchers reviewed how microplastics harm a wide range of living things, finding they cause physical damage, inflammation, oxidative stress, and reproductive problems in aquatic animals, while also carrying toxic chemicals and dangerous bacteria into organisms. Major gaps remain in understanding the effects of long-term low-dose exposure and the risks posed by even tinier nanoplastics.
Micro- and Nanoplastics on Human Health and Diseases: Perspectives and Recent Advances
This review provides a comprehensive overview of how micro- and nanoplastics enter the human body through ingestion, inhalation, and skin absorption, and how they can then travel through the bloodstream to reach virtually every organ. Researchers summarize evidence that these particles can trigger inflammation, oxidative stress, and disruption of hormonal and immune functions. The study emphasizes that the ability of these particles to cross biological barriers and accumulate in tissues makes understanding their long-term health effects an urgent research priority.
Microplastics-sources, spread and impact on the living world
This review examines microplastic sources, environmental spread, and biological impacts, covering particles ranging from 1 to 5000 µm in diameter derived from plastic degradation, industrial production, and everyday use of synthetic materials and cosmetics. The authors highlight microplastics' capacity to cross biological barriers, accumulate in tissues, and trigger inflammatory and immune responses in organisms throughout the food chain.
Environmental fate, ecotoxicity biomarkers, and potential health effects of micro- and nano-scale plastic contamination
This review provides a comprehensive overview of the environmental fate, ecotoxicity biomarkers, and potential health effects of micro- and nanoscale plastic particles. Researchers summarize how these particles move through ecosystems, accumulate in organisms, and trigger biological stress responses including oxidative damage and inflammation. The study emphasizes that while growing evidence points to harmful effects, more research is needed to understand the long-term health implications of chronic low-level exposure.
Unveiling the toxicity of micro-nanoplastics: A systematic exploration of understanding environmental and health implications
This review summarizes what is known about the toxicity of micro- and nanoplastics, noting they can cross critical barriers in the body including the blood-brain barrier. Studies in lab animals show these particles can cause DNA damage, oxidative stress, and cell death, with potential effects on the brain, heart, lungs, and skin, underscoring the need for more real-world human studies.