Papers

61,005 results
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Article Tier 2

Microplastics in Human Tissues: Sources, Distribution, Toxicological Effects, and Health Implications

Researchers reviewed the growing body of evidence that microplastics accumulate in human tissues — including lung, blood, placenta, breast milk, and heart tissue — where they can trigger inflammation, oxidative stress, and cell death. The review highlights urgent knowledge gaps around how plastic particles move through the body and what their long-term health effects may be.

2025 International Research Journal of Modernization in Engineering Technology and Science
Meta Analysis Tier 1

Systemic Accumulation and Distribution of Micro- and Nanoplastics in Human Tissues and Their Impact on Health: A Systematic Review

This systematic review synthesizes human evidence on the presence of micro- and nanoplastics in body tissues and fluids, including blood, lungs, placenta, breast milk, and liver. The research confirms that plastic particles can cross biological barriers and accumulate in multiple organ systems. While the long-term health effects are still being studied, the widespread presence of plastics inside the human body raises significant health concerns.

2026 Open Science Framework
Review Tier 2

"Unseen Dangers: The Effects of Micro- and Nanoplastics on Human Reproductive Health - A Narrative Review"

This review examines the effects of micro- and nanoplastics on human reproductive health, covering evidence from in vitro, animal, and epidemiological studies showing that plastic particles can disrupt hormone signaling, sperm function, ovarian development, and placental integrity.

2025 Recent Advances in Inflammation & Allergy Drug Discovery
Article Tier 2

Human biomonitoring of microplastics and health implications: A review

This review compiles 91 studies showing that microplastics have been detected in human blood, urine, stool, lung tissue, breast milk, semen, and placenta, confirming widespread human exposure. While our bodies have some ability to clear these particles, microplastics that accumulate in tissues may trigger inflammation, oxidative stress, gut disruption, and reproductive problems. The authors stress that more standardized monitoring methods are needed to fully understand the health consequences.

2023 Environmental Research 83 citations
Article Tier 2

Understanding the impact of nanoplastics on reproductive health: Exposure pathways, mechanisms, and implications

This review summarizes existing research on how nanoplastics (tiny plastic particles smaller than one micrometer) affect reproductive health in animals and potentially humans. Studies show that nanoplastics can accumulate in reproductive organs including the placenta, and evidence from animal studies links exposure to hormone disruption, reduced fertility, and developmental problems. The authors highlight a significant knowledge gap about nanoplastic effects on human reproduction, despite growing evidence that these particles reach our reproductive systems.

2024 Toxicology 16 citations
Review Tier 2

Microplastics and human fertility: A comprehensive review of their presence in human samples and reproductive implication

This review examines the growing evidence linking microplastic and nanoplastic exposure to potential effects on human fertility. Researchers noted that these tiny plastic particles have been detected in blood, placenta, and seminal fluid, suggesting continuous systemic exposure and the ability to cross key biological barriers. Animal studies indicate that microplastics may affect reproductive health through oxidative stress, hormonal disruption, and tissue damage, though more standardized human research is needed.

2025 Ecotoxicology and Environmental Safety 2 citations
Article Tier 2

The Microplastics and Human Health: Focus on the Reproductive System

This review examined evidence that microplastics accumulate in human reproductive tissues and evaluated their potential effects on fertility and reproductive health. The authors found microplastics detected in testes, ovaries, placenta, and semen, and summarized mechanistic evidence linking them to hormonal disruption, oxidative stress, and impaired gamete function.

2025 Quality in Sport
Systematic Review Tier 1

Exposure to micro- and nanoplastics and human reproductive outcomes: a systematic review

This systematic review summarizes existing research on whether micro and nanoplastics affect human fertility and pregnancy outcomes. While the evidence is still emerging, the review found that these particles have been detected in placenta and fetal tissue, raising important questions about potential effects on reproductive health that warrant further study.

2023 1 citations
Article Tier 2

Health Implications of Widespread Micro- and Nanoplastic Exposure: Environmental Prevalence, Mechanisms, and Biological Impact on Humans

This review summarizes how microplastics and nanoplastics enter the human body through food, air, and skin contact, then travel through the bloodstream to accumulate in various organs. Health effects range from immediate problems like pain and inflammation to long-term conditions including infertility, chronic lung disease, and potentially cancer, though the exact concentrations that build up in the body and the full extent of harm are still being studied.

2024 Toxics 20 citations
Article Tier 2

The Invisible Threat: Microplastics in Human Blood and Placenta

This review summarized current evidence on microplastic detection in human blood and placenta, discussing what is known about how these particles enter the bloodstream and reach fetal tissue. The authors highlight the potential implications for maternal and fetal health.

2024 Journal of Drug Delivery and Therapeutics 1 citations
Article Tier 2

The Plastic Within: Microplastics Invading Human Organs and Bodily Fluids Systems

This review documents the presence of microplastics in human organs and body fluids including the liver, blood, heart, placenta, breast milk, lungs, and reproductive tissues. The particles enter through ingestion, inhalation, and skin contact, and may also be introduced through invasive medical procedures. The widespread distribution of microplastics throughout the body raises concerns about their potential effects on organ function and long-term health.

2023 Environments 60 citations
Systematic Review Tier 1

A systematic review of the impacts of exposure to micro- and nano-plastics on human tissue accumulation and health

This systematic review found growing evidence that micro- and nanoplastics accumulate in human tissues including lungs, gut, and blood, with lab studies showing potential disruption to immune, reproductive, endocrine, and nervous systems. The review identifies ingestion, inhalation, and dermal contact as the three main exposure routes and highlights that the smallest nanoplastic particles pose the greatest concern due to their ability to cross biological barriers.

2023 Eco-Environment & Health 180 citations
Review Tier 2

A review on micro- and nanoplastics in humans: Implication for their translocation of barriers and potential health effects

This review compiles evidence showing that micro- and nanoplastics have been found in human blood, lungs, placenta, and other organs, and can cross protective barriers including the blood-brain and placental barriers. The accumulated evidence links these particles to inflammation, oxidative stress, hormone disruption, and potential effects on reproduction and brain health, though more research is needed to determine exact risk levels.

2024 Chemosphere 35 citations
Systematic Review Tier 1

Unveiling the presence of micro and nanoplastics in human biological matrices: A systematic review covering the latest five years from 2020 to 2025

This systematic review covering 2020-2025 confirmed the presence of micro- and nanoplastics in human blood, placenta, lungs, liver, kidneys, and other biological matrices. The findings demonstrate that plastic particles are accumulating in human tissues through ingestion, inhalation, and dermal contact, raising urgent questions about long-term health consequences.

2025 The Science of The Total Environment 1 citations
Article Tier 2

Growing concerns over ingested microplastics in humans

This paper reviews the growing body of evidence showing that microplastics have been found in various human tissues, raising public health concerns. Researchers note that while laboratory studies demonstrate microplastics can cause cellular damage, significant knowledge gaps remain regarding dose-response relationships, specific target organs, and underlying toxicological mechanisms. The study calls for improved detection technologies and thorough risk assessments to better understand the real-world health implications.

2025 Carbon Research 3 citations
Article Tier 2

Toxicological effects of micro/nano-plastics on human reproductive health: A review

This review summarizes research on how micro- and nanoplastics affect human reproductive health in both men and women. Evidence from animal and lab studies shows that these particles can accumulate in reproductive organs, disrupt hormones, damage eggs and sperm, and cause inflammation and oxidative stress. While human studies are still limited, the growing body of evidence suggests that microplastic exposure is a potential threat to fertility that warrants further investigation.

2025 Toxicology Letters 7 citations
Article Tier 2

Microplastics exposure: implications for human fertility, pregnancy and child health

This review examines growing evidence that microplastics accumulate in the human placenta and may affect pregnancy outcomes and child development. Given that exposure during pregnancy can program lifelong health in offspring, the presence of these tiny plastic particles in reproductive tissues raises important concerns about fertility, pregnancy complications, and children's health.

2024 Frontiers in Endocrinology 115 citations
Article Tier 2

"Micro and Nano Plastic as an Emerging Threat on Human Health"

This review covers the sources, environmental prevalence, and human health effects of micro- and nanoplastics, summarizing how these particles—derived from tire wear, synthetic fibers, and product breakdown—accumulate in and affect major organs including the brain, liver, kidneys, and reproductive system. It identifies gaps in clinical evidence and calls for coordinated research on long-term health impacts.

2025 International Journal of Pharmaceutical Research and Applications
Review Tier 2

Effects of micro(nano)plastics on the reproductive system: A review

This review summarizes research on how micro and nanoplastics affect the reproductive system in both animal studies and cell experiments. Evidence indicates these particles can cross biological barriers, accumulate in reproductive organs, and disrupt hormones, egg development, and sperm quality. While human studies are still limited, the animal data suggests microplastic exposure may be a meaningful concern for reproductive health.

2023 Chemosphere 42 citations
Article Tier 2

Bridging the Gaps between Microplastics and Human Health

This review summarizes how microplastics and nanoplastics enter the human body through breathing, eating, drinking, skin contact, and even transfer from mother to fetus during pregnancy. Once inside, these particles can cross tissue barriers and potentially affect cellular processes important for fetal development. While the health effects are still being studied, the evidence so far points to real concerns about reproductive and developmental impacts from our daily plastic exposure.

2024 Microplastics 28 citations
Article Tier 2

Health impacts of microplastic and nanoplastic exposure

This review examines the growing evidence that micro- and nanoplastics can cross barriers in the lungs and gut, enter the bloodstream, and reach organs like the brain, placenta, and reproductive system. Early clinical studies suggest links to immune changes, heart problems, and reproductive effects, though more research is needed. Better methods for measuring plastic exposure in humans are critical to understanding the true health risks.

2025 Nature Medicine 50 citations
Systematic Review Tier 1

Effects of Microplastics on Human Physiology: Mechanisms of Toxicity and Health Risks

This systematic review of 48 studies found that microplastics have been detected in human blood, placenta, and reproductive tissues, showing they can cross biological barriers. The most common harmful effects include oxidative stress, inflammation, hormonal disruption, and DNA damage, raising serious questions about long-term health consequences.

2025 Zenodo (CERN European Organization for Nuclear Research)
Meta Analysis Tier 1

Health Impacts of Micro- and Nanoplastics in Humans: Systematic Review of In Vivo Evidence

This meta-analysis reviews 25 studies that directly measured micro- and nanoplastics in living human tissues and fluids. The evidence confirms that plastic particles accumulate in multiple organ systems, including the heart, reproductive organs, and gut, and are associated with inflammation and functional problems. This is some of the strongest direct evidence that microplastics are present inside our bodies and may be affecting our health.

2025 1 citations
Article Tier 2

The Impact of Microplastics on Human Health: a Comprehensive Review

This comprehensive review summarizes how microplastics — found in air, water, and food — enter the human body through ingestion, inhalation, and skin contact, and have been detected in organs including the lungs, liver, kidneys, placenta, and brain. Microplastic exposure has been associated with respiratory disorders, gut inflammation, reproductive toxicity, immune dysfunction, and potential neurological effects.

2022 Journal of Emerging Technologies and Innovative Research