We can't find the internet
Attempting to reconnect
Something went wrong!
Hang in there while we get back on track
Microplastics and human fertility: A comprehensive review of their presence in human samples and reproductive implication
AI summary Read the abstract
This review examines the growing evidence linking microplastic and nanoplastic exposure to potential effects on human fertility. Researchers noted that these tiny plastic particles have been detected in blood, placenta, and seminal fluid, suggesting continuous systemic exposure and the ability to cross key biological barriers. Animal studies indicate that microplastics may affect reproductive health through oxidative stress, hormonal disruption, and tissue damage, though more standardized human research is needed.
In recent years, infertility has started to represent a major global public health problem. A growing number of evidences regarding the involvement of environmental factors in the decline of reproductive function have already been highlighted by the specialized literature. Microplastics (MPs) and nanoplastics (NPs) are ubiquitous particles present in all types of ecosystems. They have recently been detected in various human biological samples, including blood, placenta and seminal fluid. This suggests a continuous systemic exposure to this type of pollutant, as well as its capacity to penetrate the key barriers of the human body and trans-generational transfer. The purpose of this work was to critically review the current literature regarding the link between exposure to MPs/NPs and the possible interaction with human infertility. Relevant studies on animal models, as well as the molecular implications and the main access routes of MPs/NPs in the human body, were also highlighted. Studies on animal models have highlighted the toxicity of this type of pollutant manifested through different size-polymer dependent mechanisms of action, including gonadal histological alterations, induction of oxidative stress, cellular apoptosis and hormonal dysfunctions. An integrative perspective on the reproductive risks associated with small-sized polymeric materials is provided. Furthermore, the need to develop standardized methods and protocols for MPs detection in human samples is emphasized, to improve our understanding of the toxic effects on human health and to guide potential preventive or therapeutic strategies for this type of toxicity.
More Papers Like This
Exposure to micro- and nanoplastics and human reproductive outcomes: a systematic review
AI summary Read the abstract
This systematic review summarizes existing research on whether micro and nanoplastics affect human fertility and pregnancy outcomes. While the evidence is still emerging, the review found that these particles have been detected in placenta and fetal tissue, raising important questions about potential effects on reproductive health that warrant further study.
Plastics in human reproductive tissues: A systematic review of detection, characterization, and effects on fertility.
AI summary Read the abstract
This review summarizes 41 studies on tiny plastic particles found in human reproductive tissues, including semen, testis, follicular fluid, and placenta. These particles were linked to cell stress, metabolic changes, and in some studies, poor sperm motility, though effects on ovarian markers and fertility outcomes were inconsistent across studies.
Toxicological effects of micro/nano-plastics on human reproductive health: A review
AI summary Read the abstract
This review summarizes research on how micro- and nanoplastics affect human reproductive health in both men and women. Evidence from animal and lab studies shows that these particles can accumulate in reproductive organs, disrupt hormones, damage eggs and sperm, and cause inflammation and oxidative stress. While human studies are still limited, the growing body of evidence suggests that microplastic exposure is a potential threat to fertility that warrants further investigation.
Microplastics and reproductive health: implications for human health and areas for future research
AI summary Read the abstract
Tiny plastic bits called microplastics have been found in human testes, semen, ovarian fluid, and placentas, and this review of existing research suggests they may harm fertility by triggering inflammation, cell damage, and hormone disruption. While scientists are still figuring out exactly how much exposure is harmful and which types of plastic pose the biggest risk, the growing evidence is a reason to pay attention to reducing everyday plastic exposure. More research is needed before we know the full picture, but this is an area worth watching closely.
Effects of micro(nano)plastics on the reproductive system: A review
AI summary Read the abstract
This review summarizes research on how micro and nanoplastics affect the reproductive system in both animal studies and cell experiments. Evidence indicates these particles can cross biological barriers, accumulate in reproductive organs, and disrupt hormones, egg development, and sperm quality. While human studies are still limited, the animal data suggests microplastic exposure may be a meaningful concern for reproductive health.
Research digests by email
When a large batch of papers lands in the Atlas, we read through it and send a short write-up of what stood out.