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"Micro and Nano Plastic as an Emerging Threat on Human Health"

International Journal of Pharmaceutical Research and Applications 2025
Vijay Kumar Thakur, Vishal Chaudhary, Vikash Vikash, Vipasha Vipasha

Summary

This review covers the sources, environmental prevalence, and human health effects of micro- and nanoplastics, summarizing how these particles—derived from tire wear, synthetic fibers, and product breakdown—accumulate in and affect major organs including the brain, liver, kidneys, and reproductive system. It identifies gaps in clinical evidence and calls for coordinated research on long-term health impacts.

The term "plastics," which comes from the Greek word "plastikos," refers to a broad category of synthetic and semi-synthetic materials that have not only contributed to human development but also caused serious problems for the environment and human health. Larger plastic objects break down to produce microplastics (less than 5 mm) and nanoplastics (less than 0.1 µm), which are dangerous to human health and common in ecosystems. Both marine and terrestrial habitats include these microscopic plastic particles, which come from sources like tire wear, synthetic fibers, plastic breakdown, personal care items, and industrial operations. Their broad rate causes worry about how they may affect important organs like the brain, liver, skin, kidneys, reproductive system, and gastrointestinal tract. Liver damage, neurotoxicity, and cancer have all been connected to micro and nanoplastics. To solve this problem, several remediation techniques have been developed, such as physical, chemical, biological, and nano-remediation; nonetheless, there are still obstacles in the way of completely getting clear of these contaminants.

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