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20 resultsShowing papers similar to Ameliorative effects of mulberry fruit anthocyanin extract on gut microbiota and liver metabolites in high-fat and high-cholesterol diet-fed ApoE−/− mice
ClearGut microbiota remodeling drived by dietary millet protein prevents the metabolic syndrome
Researchers found that millet bran protein extract prevented metabolic syndrome in high-fat diet mice by remodeling gut microbiota and reducing obesity, chronic inflammation, and insulin resistance. The protective effects were linked to specific gut microbial metabolites influenced by dietary millet protein.
An Ilex latifolia‐containing compound tea regulates glucose–lipid metabolism and modulates gut microbiota in high‐fat diet‐fed mice
This study investigated how a compound tea containing Kuding Tea, green tea, and Luohan fruit affects glucose and lipid metabolism in mice fed a high-fat diet. Researchers found that the tea blend helped regulate metabolic parameters and modulated gut microbiota composition, suggesting potential benefits for managing metabolic health.
Characterizing the Gut Microbial Metabolic Profile of Mice with the Administration of Berry-Derived Cyanidin-3-Glucoside
This paper is not about microplastics — it characterizes how the berry-derived compound cyanidin-3-glucoside alters gut microbiome composition and metabolic profiles in mice.
Erchen Decoction Alleviates High-Fat Diet + AOM/DSS-Induced CRC by Ameliorating Cholesterol-Bile Acid Metabolism Disorder through Regulating FXR and the Gut Microbiota
Researchers found that Erchen Decoction, a traditional Chinese medicine formula, alleviates colorectal cancer progression in a high-fat diet mouse model by correcting cholesterol-bile acid metabolism disorders through modulation of FXR signaling and gut microbiota composition.
Black Lycium barbarum polysaccharide attenuates LPS-induced intestine damage via regulation gut microbiota
Researchers studied whether a polysaccharide from black Lycium barbarum could protect against intestinal damage caused by bacterial toxins in mice. They found that the supplement alleviated intestinal tissue damage and improved gut microbiota diversity by promoting beneficial bacteria. The study suggests that this plant-derived polysaccharide may help maintain intestinal health by modulating the gut microbial community.
Mechanism of Mulberry Leaves and Black Sesame in Alleviating Slow Transit Constipation Revealed by Multi-Omics Analysis
Researchers examined how mulberry leaves and black sesame alleviate slow transit constipation in a mouse model, measuring gut motility, microbiota composition, and intestinal gene expression. Both dietary interventions increased beneficial bacteria, enhanced gut peristalsis, and upregulated genes associated with intestinal motility, supporting their traditional use for digestive health.
Cyanidin-3- O-glucoside alleviates trimethyltin chloride-induced neurodegeneration by maintaining glutamate homeostasis through modulation of the gut microbiota
Researchers found that cyanidin-3-O-glucoside, a common dietary anthocyanin found in berries and other foods, helped protect against chemically induced neurodegeneration in mice by restoring glutamate balance in the brain. The study suggests that this protective effect is mediated through modulation of gut microbiota, highlighting a potential gut-brain connection in neuroprotection.
Immune mechanism of gut microbiota and its metabolites in the occurrence and development of cardiovascular diseases
This review examines immune mechanisms linking gut microbiota and its metabolites to cardiovascular diseases, explaining how disruptions in the microbiota-immune balance contribute to conditions such as atherosclerosis, hypertension, and heart failure.
Protocatechuic Acid Alleviates Dextran-Sulfate-Sodium-Induced Ulcerative Colitis in Mice via the Regulation of Intestinal Flora and Ferroptosis
Researchers found that protocatechuic acid, a naturally occurring compound found in many fruits and vegetables, helped alleviate ulcerative colitis in mice by restoring healthy gut bacteria and reducing a type of cell death called ferroptosis. The treatment improved intestinal barrier integrity and reduced inflammation. This is relevant to microplastics research because gut barrier damage is a key concern with microplastic ingestion.
Selenium-containing polysaccharide from Spirulina platensis alleviates Cd-induced toxicity in mice by inhibiting liver inflammation mediated by gut microbiota
Researchers found that selenium-containing polysaccharide from Spirulina platensis alleviates cadmium-induced liver toxicity in mice by modulating gut microbiota composition and suppressing inflammatory pathways, suggesting a protective role against heavy metal exposure.
Protective Effect of Resveratrol on Kidney Disease and Hypertension Against Microplastics Exposure in Male Juvenile Rats
Researchers investigated whether resveratrol, a natural plant compound, could protect young rats from kidney damage and high blood pressure caused by microplastic exposure. They found that microplastics elevated blood pressure and creatinine levels through oxidative stress, and that resveratrol treatment effectively prevented these effects. The study suggests resveratrol may offer protective benefits against organ damage linked to microplastic exposure, partly by improving gut microbiota balance.
Anthocyanins as protectors of gut microbiota: mitigating the adverse effects of microplastic-induced disruption
This review examines how anthocyanins, bioactive compounds found in berries and other pigmented plants, may protect gut microbiota from disruption caused by microplastic exposure. Researchers synthesized evidence suggesting that anthocyanins counteract microplastic-induced oxidative stress and inflammation in the gut. The findings indicate that dietary anthocyanins could serve as a protective factor against the adverse effects of microplastics on digestive health.
Food-derived cyanidin-3-O-glucoside reverses microplastic toxicity via promoting discharge and modulating the gut microbiota in mice
Researchers found that cyanidin-3-O-glucoside (C3G), a naturally occurring anthocyanin compound found in many fruits and vegetables, helped reduce the harmful effects of polystyrene microplastics in mice. C3G supplementation promoted the excretion of microplastics, reduced tissue accumulation, and alleviated oxidative stress and inflammation caused by the particles. The study also showed that C3G helped restore healthy gut microbiota that had been disrupted by microplastic exposure.
Modulation of Gut Microbial Metabolism by Cyanidin-3-O-Glucoside in Mitigating Polystyrene-Induced Colonic Inflammation: Insights from 16S rRNA Sequencing and Metabolomics
A natural plant compound called cyanidin-3-O-glucoside (C3G), found in red bayberry and other berries, reduced colon inflammation caused by polystyrene microplastic exposure in mice. C3G worked by reshaping the gut bacteria community and restoring healthy levels of anti-inflammatory signaling molecules. This suggests that certain dietary antioxidants may help protect the gut from damage caused by microplastic exposure.
Gut microbiota and liver metabolomics reveal the potential mechanism of Lactobacillus rhamnosus GG modulating the liver toxicity caused by polystyrene microplastics in mice
Researchers found that the probiotic Lactobacillus rhamnosus GG helped protect mice from liver damage caused by polystyrene microplastic exposure. The probiotic worked by restoring healthy gut bacteria and normalizing liver metabolic pathways disrupted by the microplastics. The study suggests that supporting gut health through beneficial bacteria may help mitigate some of the toxic effects microplastics have on the liver.
Unraveling the impact of micro- and nano-sized polymethyl methacrylate on gut microbiota and liver lipid metabolism: Insights from oral exposure studies
Mice that drank water containing tiny acrylic-type plastic particles (PMMA) for eight weeks developed liver damage, gut microbiome changes, and disrupted fat metabolism. The plastic particles accumulated in the liver and colon, triggering oxidative stress and activating pathways that increased cholesterol production. This study suggests that chronic exposure to even common plastic types through drinking water could harm liver health by disrupting the gut-liver connection.
Multi-Omics Analysis of the Gut-Liver Axis Reveals the Mechanism of Liver Injury in Colitis Mice
Researchers used multi-omics analysis to reveal that liver injury in colitis mice is linked to intestinal dysbiosis and altered host-microbiota interactions, with gut bacterial shifts correlating to immune and metabolic changes in the liver.
Resveratrol Butyrate Esters Reduce Hypertension in a Juvenile Rat Model of Chronic Kidney Disease Exacerbated by Microplastics
Researchers found that resveratrol butyrate esters reduced high blood pressure in young rats that had both chronic kidney disease and microplastic exposure. The protective effects worked by improving nitric oxide levels, regulating the body's blood pressure control system, and positively shifting gut bacteria composition. The study suggests that certain natural compounds may help counteract the cardiovascular harm associated with microplastic exposure.
Inhibitory Effects of Jiuzao Polysaccharides on Alcoholic Fatty Liver Formation in Zebrafish Larvae and Their Regulatory Impact on Intestinal Microbiota
Researchers investigated the protective effects of Laowuzeng Jiuzao polysaccharides on ethanol-induced alcoholic fatty liver in zebrafish larvae, finding that the polysaccharides reduced hepatic damage and regulated intestinal microbiota composition, suggesting therapeutic potential for alcohol-related liver disease.
Anti-diabetic effect of anthocyanin cyanidin-3-O-glucoside: data from insulin resistant hepatocyte and diabetic mouse
Researchers showed that cyanidin-3-O-glucoside (C3G) — a natural pigment found in blueberries and other dark fruits — can improve insulin sensitivity in both liver cell cultures and diabetic mice by suppressing a protein that blocks insulin signaling. The findings suggest C3G could be a dietary strategy for managing type 2 diabetes.