We can't find the internet
Attempting to reconnect
Something went wrong!
Hang in there while we get back on track
Papers
61,005 resultsShowing papers similar to Micro-Embolic Events and Their Clearing in the Brain. A Narrative Review.
ClearMicroplastics in the bloodstream can induce cerebral thrombosis by causing cell obstruction and lead to neurobehavioral abnormalities
Researchers discovered that microplastics in the bloodstream can cause blood clots in the brain by getting swallowed by immune cells that then block tiny blood vessels. These blockages reduced blood flow and caused neurological problems in mice. This reveals a new way microplastics may harm the brain, not by crossing into brain tissue directly, but by disrupting blood circulation.
The impact of microplastics on neurodegenerative diseases and underlying molecular mechanisms: A narrative review
This review explores how microplastics that accumulate in the environment can reach the brain through inhalation or by crossing the blood-brain barrier. Researchers examined evidence suggesting that microplastics may contribute to the onset or acceleration of neurodegenerative conditions by triggering harmful responses in brain cells. The study calls for stronger environmental policies, better detection methods, and further research into potential therapeutic interventions.
Mechanisms of micro- and nanoplastics on blood-brain barrier crossing and neurotoxicity: Current evidence and future perspectives
This review examines evidence that micro- and nanoplastics can cross the blood-brain barrier, the protective shield around the brain, through multiple pathways including disrupting the barrier's tight junctions and being transported inside cells. Once in the brain, these particles may cause damage through oxidative stress, inflammation, mitochondrial dysfunction, and disrupted iron metabolism, with effects worsened when plastics carry other pollutants like heavy metals.
Crossing barriers – tracking micro- and nanoplastic pathways into the human brain
Researchers tracked potential pathways by which micro- and nanoplastics may enter the human brain, examining both in vitro cell models and post-mortem brain tissue. They found that human monocytes rapidly internalized polystyrene particles into endocytic vesicles and mitochondria, and detected plastic particles in brain tissue samples, providing evidence that nanoplastics may be capable of crossing brain barriers.
Microplastics and Their Effect on Neuroglia: A Narrative Review
This narrative review examines how microplastics — entering the body through inhalation, ingestion, and skin contact — may accumulate in neuroglial cells of the brain, raising concern about their role in neuroinflammation and neurodegenerative disease progression.
Abstract TP089: Micro and Nano plastics in Cerebrovascular Health: A systematic Review of Current Evidence and Research Directions
This systematic review examines emerging evidence linking micro- and nanoplastics to cerebrovascular health problems. Studies found plastic particles in human brain blood vessels and arterial plaques, with evidence suggesting they may promote inflammation and oxidative stress that could contribute to stroke risk.
Micro- and Nanoplastics in the Brain: A Scoping Review Protocol on Their Presence, Neurotoxic Effects, and Implications for Human Health
This scoping review protocol outlines a systematic approach to mapping scientific evidence on the presence of micro- and nanoplastics in the brain, their neurotoxic effects, and potential implications for human health. The review will chart findings from both human studies and experimental models to identify key mechanisms, affected brain regions, and knowledge gaps in this emerging field.
Micro-nanoplastics in the central nervous system: Evidence, mechanisms and perspectives
This review examines evidence that micro- and nanoplastics can cross the blood-brain barrier and cause neurotoxicity through oxidative stress, neuroinflammation, and disruption of neurotransmitter signaling. While clinical studies have confirmed the presence of plastic particles in human brain tissue and cerebrospinal fluid, the authors note that methodological limitations and inconsistent quality controls currently prevent establishing a definitive causal link to neurological conditions.
Brain under siege: the role of micro and nanoplastics in neuroinflammation and oxidative stress
This review examines emerging evidence that micro- and nanoplastics can cross the blood-brain barrier and accumulate in nervous tissue, potentially triggering neuroinflammation and oxidative stress. Researchers summarized findings showing these particles may act as neurotoxicants that contribute to synaptic dysfunction and pathological changes in brain cells. The study highlights the need for further research into how chronic plastic particle exposure may affect central nervous system health over time.
Assessing the Impact of Microplastics on Brain Chemistry: The Need for a Comprehensive Policy Framework to Mitigate Toxicity
This review examines the growing evidence that microplastics can cross biological barriers, accumulate in brain tissue, and affect neurological function. Researchers found that microplastic exposure has been linked to neurotoxicity, oxidative stress, and inflammation in the brain, with potential implications for neurotransmitter systems and cognitive function. The study calls for comprehensive regulatory measures to limit microplastic pollution and further research into the long-term neurological health effects.
Micro- and Nanoplastics in the Brain: A Scoping Review Protocol on Their Presence, Neurotoxic Effects, and Implications for Human Health
This scoping review protocol maps scientific evidence on the presence of micro- and nanoplastics in the brain, their neurotoxic effects, and implications for human health, drawing from both human studies and experimental models. The protocol follows JBI methodology to systematically chart available evidence.
Evidence, Mechanisms, and Clinical Implications of Microplastics and Nanoplastics As Emerging Cardiovascular Risk Factors: A Narrative Review
This review examines growing evidence that micro- and nanoplastics may contribute to cardiovascular health risks, with researchers having found these particles in human artery plaques and blood clots. Evidence indicates that the particles can enter the bloodstream, trigger inflammation, damage blood vessel walls, and potentially increase the risk of heart attacks and strokes. While the evidence is not yet conclusive, the study highlights an emerging area of concern that warrants further investigation into how everyday plastic exposure may affect heart and blood vessel health.
Microplastics block blood flow in the brain, mouse study reveals
A mouse study using real-time imaging found that cells stuffed with microplastics can form clumps that block blood flow in the brain, affecting the animals' ability to move. This research raises concerns about potential neurological effects of microplastic accumulation in the bodies of mammals.
Micro- and Nanoplastics as a Potential Risk Factor for Stroke: A Systematic Review
This systematic review assessed the potential link between micro- and nanoplastics and stroke risk. It found that plastic particles have been detected in human blood vessels and arterial plaques, and may contribute to inflammation and blood vessel damage — factors that could increase the risk of stroke.
A perspective on the potential impact of microplastics and nanoplastics on the human central nervous system
This paper discusses evidence that micro- and nanoplastics may be able to cross the blood-brain barrier, the protective layer that normally keeps harmful substances out of the brain. If confirmed in humans, this could mean plastic particles contribute to neurodegenerative diseases, though more research is needed to understand the extent of this risk.
Exploring Vascular Contributions to Cognitive Impairment with Focus on Small-Vessel Disease of White Matter and Micro/nanoplastics
Researchers propose a pathology classification framework for vascular causes of cognitive impairment and highlight the recent discovery of micro/nanoplastics in human brain tissue as a factor that may reshape understanding of vascular dementia by linking plastic accumulation to cerebrovascular damage.
The Urgent Need to Assess and Prevent the Deposits of Microplastics and Nanoplastics in Our Brain
This peer-reviewed commentary argues for urgent research into the deposition of microplastics and nanoplastics in the human brain, calling for standardized methods and more investigation into potential neurological consequences.
Insights into the toxic effects of micro-nano-plastics on the human brain and their relationship with the onset of neurological diseases: A narrative review.
This review examined toxic effects of micro and nano-plastics (MNPs) on the human brain, linking MNP exposure to neuroinflammation, oxidative stress, disruption of the blood-brain barrier, and progression toward neurodegenerative diseases. The authors synthesized evidence from cell studies, animal models, and emerging human data.
Nano/micro-plastic, an invisible threat getting into the brain
This editorial highlights growing evidence that nano- and microplastics can cross the blood-brain barrier through the bloodstream and nasal passages, triggering neuroinflammation and potentially contributing to brain disorders. The authors call for urgent multidisciplinary research to understand the pathways by which these plastic particles reach the brain and what long-term neurological damage they may cause.
Pathways, Mechanisms, and Therapeutic Strategies of Neurotoxicity Induced by Micro- and Nanoplastics
This review examined the pathways by which micro- and nanoplastics reach the brain—via the gut-brain axis, respiratory tract, and circulatory system—and the mechanisms by which they induce neurotoxicity, including neuroinflammation, oxidative stress, and disruption of neurotransmitter systems. The authors surveyed emerging therapeutic strategies, highlighting antioxidant supplementation and anti-inflammatory interventions as the most promising current approaches.
Overall effects of microplastics on brain
This review synthesizes research on how micro- and nanoplastics affect the brain, finding evidence that these particles can cross critical biological barriers including the blood-brain barrier and placenta to reach the central nervous system. Researchers found that once in the brain, microplastics may trigger oxidative stress, inflammation, and disruption of neurotransmitter systems. The study suggests that microplastic exposure represents an emerging concern for neurological health, though more research is needed to fully characterize the risks.
An overview of research on the association between microplastics and central nervous system disorders
This review explores the growing body of evidence linking microplastic exposure to central nervous system disorders. Researchers found that microplastics can enter the body through ingestion, inhalation, and skin absorption, then accumulate in neural tissues where they trigger inflammation, oxidative stress, and neuronal damage. The study aims to provide a scientific foundation for assessing the public health risks of microplastic exposure on brain health.
The effects of micro- and nanoplastics on the central nervous system: A new threat to humanity?
This review summarizes growing evidence that micro- and nanoplastics can cross the blood-brain barrier and damage the central nervous system through inflammation, oxidative stress, and disruption of brain chemicals. The authors note that microplastic exposure has been linked to memory and behavior changes in animals and may contribute to neurodegenerative diseases like Parkinson's, though direct human evidence is still limited.
Transport of microplastics in the body and interaction with biological barriers, and controlling of microplastics pollution
This review summarizes how microplastics enter the human body through food, water, and air, and what happens when they encounter the body's protective barriers like the gut lining, skin, and blood-brain barrier. Smaller microplastics can cross these barriers and accumulate in organs, potentially causing inflammation and other harmful effects. The review also covers emerging methods for removing microplastics from the environment to reduce human exposure.