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Article ? AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button. Tier 2 ? Original research — experimental, observational, or case-control study. Direct primary evidence. Human Health Effects Nanoplastics Policy & Risk Sign in to save

Micro- and Nanoplastics in the Brain: A Scoping Review Protocol on Their Presence, Neurotoxic Effects, and Implications for Human Health

OSF Preprints (OSF Preprints) 2026
João Pedro Araújo Herculano, Kayke Kauã de Siqueira, Geisa Maria de Sousa, Geisa Maria de Sousa, Fábio Antônio Mota Fonseca da Silva, Fábio Antônio Mota Fonseca da Silva

Summary

This scoping review protocol outlines a systematic approach to mapping scientific evidence on the presence of micro- and nanoplastics in the brain, their neurotoxic effects, and potential implications for human health. The review will chart findings from both human studies and experimental models to identify key mechanisms, affected brain regions, and knowledge gaps in this emerging field.

Body Systems
Nervous

This scoping review protocol aims to map the scientific evidence on the presence of micro- and nanoplastics in the brain, their neurotoxic effects, and potential implications for human health. Evidence from human studies and experimental models will be systematically charted following JBI methodology and PRISMA-ScR guidelines to identify key mechanisms, affected brain regions, and knowledge gaps.

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