Papers

61,005 results
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Article Tier 2

Effects of Long-Term Triclosan Exposure on Microbiota in Zebrafish

Long-term exposure to triclosan at environmentally relevant concentrations significantly altered gut microbiota composition in zebrafish, reducing microbial diversity and shifting community structure in ways that could affect host immune function and metabolism.

2021 Frontiers in Microbiology 10 citations
Article Tier 2

Effect of chlorpyrifos on freshwater microbial community and metabolic capacity of zebrafish

Researchers exposed zebrafish and their surrounding water to chlorpyrifos, a widely used pesticide, and found it disrupted the diversity of aquatic microbes, increased dangerous antibiotic-resistant bacteria, and altered the gut metabolism of fish — raising concerns about the ecological and food-safety risks of pesticide runoff into waterways.

2023 Ecotoxicology and Environmental Safety 15 citations
Article Tier 2

The zebrafish gut microbiome influences benzo[a]pyrene developmental neurotoxicity

Researchers found that the gut microbiome of zebrafish influences developmental neurotoxicity caused by benzo[a]pyrene, a polycyclic aromatic hydrocarbon, showing that microbial community composition modifies how the host responds to early-life toxicant exposure. The study highlighted gut-brain axis interactions as an important dimension of environmental toxicology.

2024 Research Square (Research Square) 1 citations
Article Tier 2

The Role of Danio rerio in Understanding Pollutant-Induced Gut Microbiome Dysbiosis in Aquatic Ecosystems

This review examines how freshwater pollutants—including pesticides, heavy metals, antibiotics, dyes, and microplastics—disrupt gut microbiome composition in zebrafish and other aquatic animals. It highlights the zebrafish model as a key tool for understanding pollutant-driven microbiome dysbiosis and its metabolic consequences.

2025 Toxics
Article Tier 2

Gut microbiota of aquatic organisms: A key endpoint for ecotoxicological studies

This review examines how environmental contaminants including microplastics, pesticides, heavy metals, and pharmaceuticals affect the gut microbiota of aquatic organisms. Researchers highlight that changes in gut bacterial communities can serve as sensitive indicators of pollution exposure and may have downstream effects on host fitness. The study calls for improved methodologies to better link contaminant-induced shifts in gut microbiota to measurable health outcomes in aquatic species.

2019 Environmental Pollution 261 citations
Article Tier 2

Dysregulation of gut health in zebrafish by differentially charged nanoplastic exposure: an integrated analysis of histopathology, immunology, and microbial informatics

Researchers studied how nanoplastics with different surface charges affect gut health in zebrafish using histopathology, immunology, and microbial analysis. The study found that gut damage and microflora disturbance caused by nanoplastic ingestion significantly depended on the surface functional groups of the particles.

2023 Environmental Science Nano 22 citations
Article Tier 2

Effects of Aroclor 1254 on Intestinal Immunity, Metabolism, and Microflora in Zebrafish

Zebrafish exposed to the PCB mixture Aroclor 1254 for 21 days at concentrations of 5-15 micrograms per liter showed intestinal inflammation, oxidative stress, gut microbiome disruption, and altered metabolomics profiles in a dose-dependent manner. The results demonstrate that PCBs impair intestinal barrier function and gut health, potentially contributing to systemic toxicity through increased gut permeability.

2022 Frontiers in Nutrition 10 citations
Article Tier 2

Chronic Exposure of Adult Zebrafish to Polyethylene and Polyester-based Microplastics: Metabolomic and Gut Microbiome Alterations Reflecting Dysbiosis and Resilience

Researchers exposed adult zebrafish to polyethylene and polyester microplastics at environmentally relevant concentrations and found significant disruptions to metabolic pathways and gut microbiome composition. Polyethylene primarily affected cell membrane compounds and inflammation-related metabolites, while polyester altered lipid metabolism and gut bacterial interactions. The study reveals that chronic microplastic exposure can cause subtle but meaningful shifts in fish metabolism and gut health, even at low concentrations.

2024 Journal of Hazardous Materials 9 citations
Article Tier 2

Environmental Cadmium Exposure Perturbs Gut Microbial Dysbiosis in Ducks

Environmental cadmium exposure in ducks was found to perturb gut microbial diversity and community composition, with dysbiosis patterns suggesting that heavy metal contamination in agricultural environments can impair gut health in waterfowl.

2023 Veterinary Sciences 3 citations
Article Tier 2

Exploring the impact of antibiotics, microplastics, nanoparticles, and pesticides on zebrafish gut microbiomes: Insights into composition, interactions, and health implications

This review summarizes how antibiotics, microplastics, nanoparticles, and pesticides each affect the gut microbiome of zebrafish, a widely used model for studying human health impacts. Researchers found that all four types of contaminants can significantly alter gut bacterial composition and disrupt metabolic and immune functions. The study highlights that combined exposures to multiple pollutants may have compounding effects on gut health that are more harmful than any single contaminant alone.

2023 Chemosphere 19 citations
Article Tier 2

The potential influence of food additives and contaminants on the gut microbiota: A comprehensive review

This comprehensive review examines how food additives and contaminants, including pesticides, heavy metals, microplastics, and antibiotics, affect the gut microbiota. Researchers found that these substances can disrupt the balance of gut microbes, leading to inflammation, gastrointestinal injury, and altered production of beneficial short-chain fatty acids. The study emphasizes the need for further research into the mechanisms by which dietary contaminants affect gut health and overall wellbeing.

2025 Food and Chemical Toxicology 1 citations
Article Tier 2

In vivo toxicity of industrial biocide containing 2,2-Dibromo-3-nitrilopropionamide in adult and zebrafish larvae

This paper is not about microplastics; it tests the toxicity of an industrial biocide (DBNPA) on zebrafish embryos and adults, finding developmental abnormalities at higher concentrations.

2023
Article Tier 2

The probiotic SLAB51 as agent to counteract BPA toxicity on zebrafish gut microbiota -liver-brain axis

Researchers tested whether the probiotic supplement SLAB51 could counteract the harmful effects of bisphenol A (BPA), a plastic-derived chemical, in zebrafish and found it significantly restored healthy gut bacteria, reduced liver damage, and protected the brain — suggesting probiotics may help offset harm from plastic-associated chemical exposure.

2023 The Science of The Total Environment 21 citations
Article Tier 2

Acute exposure to microplastics induces metabolic disturbances and gut dysbiosis in adult zebrafish (Danio rerio)

Researchers exposed adult zebrafish to polyethylene and polyester microplastics and used untargeted metabolomics and gut microbiome analysis to assess the effects. The study found that acute microplastic exposure caused significant metabolic disturbances and gut dysbiosis, altering key metabolites involved in lipid and amino acid metabolism.

2022 Ecotoxicology and Environmental Safety 65 citations
Article Tier 2

Plastics in our water: Fish microbiomes at risk?

This review examined how microplastics and leached plasticizers affect the gut microbiomes of freshwater and marine fish, summarizing evidence for dysbiosis and reduced microbial diversity and discussing potential consequences for fish immunity, metabolism, and environmental fitness.

2021 Comparative Biochemistry and Physiology Part D Genomics and Proteomics 25 citations
Article Tier 2

Legacy metal contamination is reflected in the fish gut microbiome in an urbanised estuary

Researchers found that legacy metal contamination in a heavily urbanized estuary in Australia is altering the gut microbiome of local fish, with metal-exposed fish harboring more potentially harmful and inflammation-linked bacteria. This shows that gut microbiome changes in fish can serve as a sensitive biological indicator of environmental pollution, even when the contamination occurred decades ago.

2022 Environmental Pollution 24 citations
Article Tier 2

Microplastic Exposure Across Trophic Levels: Effects on the Host Microbiota of Freshwater Organisms

Researchers investigated how microplastic exposure affects the gut bacteria communities of freshwater organisms including fish, invertebrates, and crustaceans. Microplastics—particularly when combined with pesticides—altered gut microbiota composition, which could impair digestion, immunity, and overall health of freshwater species.

2021 1 citations
Article Tier 2

Multi-omics association pattern between gut microbiota and host metabolism of a filter-feeding fish in situ exposed to microplastics

Scientists exposed filter-feeding fish to environmentally realistic levels of microplastics and found that the particles reshaped gut bacteria communities, which in turn altered the fish's liver metabolism through changes in amino acid processing. This gut-microbiome-to-organ connection matters because it shows microplastics may affect human health not just through direct toxicity but by disrupting the beneficial bacteria in our digestive systems.

2025 Environment International 11 citations
Article Tier 2

Modern research on the study of the intestinal microbiome in fish (review)

This review examines recent research on the intestinal microbiome of fish, synthesizing findings on microbiome composition across more than 100 teleost species and exploring the microbiome as a potential biomarker for fish health and aquaculture optimization.

2023 Animal Husbandry and Fodder Production 4 citations
Article Tier 2

A probiotic for preventing microplastic toxicity: Clostridium dalinum mitigates microplastic-induced damage via microbiota-metabolism-barrier interactions

Using metagenomics and metabolomics, this study found that the probiotic bacterium Clostridium dalinum reduced microplastic-induced gut damage in mice by modulating gut microbiota composition, metabolic pathways, and intestinal barrier integrity.

2025 Current Research in Food Science
Review Tier 2

Application of intestinal microbiota in marine fish for assessing the toxicity of typical pollutants: a literature review

This review examines how the gut microbiota of marine fish can serve as biomarkers for assessing the toxic effects of ocean pollutants, including microplastics, heavy metals, antibiotics, and petroleum hydrocarbons. The study highlights that changes in key microbial communities in fish intestines reflect environmental contamination levels and could provide valuable indicators for monitoring marine ecosystem health.

2025 PeerJ 1 citations
Article Tier 2

Bacterial communities in co-cultured fish intestines and rice field soil irrigated with aquaculture wastewater

Bacterial communities in fish intestines and rice field soil were compared in an integrated aquaculture-agriculture system where fields are irrigated with fish farm wastewater. Results showed that fish intestinal bacteria influenced the microbial communities in the irrigated soil. Understanding these interactions is important for managing food safety and ecosystem health in aqua-agriculture systems.

2022 AMB Express 4 citations
Article Tier 2

Effects of Polyethylene Microplastics Exposureon Intestinal Flora of Zebrafish

Polyethylene microplastic exposure altered gut microbiota composition in zebrafish in both size-dependent and time-dependent ways, with smaller particles and longer exposure durations producing greater shifts in bacterial community structure, including increases in potential pathobionts and decreases in beneficial genera.

2021 Polish Journal of Environmental Studies 12 citations
Article Tier 2

Effects of environmental factors on host-microbiota interactions in the guts of aquatic organisms: A review

This review synthesizes how environmental stressors — including microplastics, heavy metals, photoperiod, and aquaculture feed additives — alter gut microbiota in fish and aquatic invertebrates, identifying common patterns of microbial disruption and compromised gut barrier integrity.

2025 Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology 2 citations