Papers

61,005 results
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Article Tier 2

Validated method for polystyrene nanoplastic separation in aqueous matrices by asymmetric-flow field flow fraction coupled to MALS and UV–Vis detectors

Researchers developed and fully validated a method to accurately measure nanoplastic particle sizes (30–490 nm) in water using a technique that combines flow separation with light-scattering detection. Having a validated analytical method is a critical step for standardizing how nanoplastics are measured across laboratories, enabling more consistent assessment of their environmental risks.

2023 Microchimica Acta 14 citations
Article Tier 2

A method for efficient separation of polystyrene nanoplastics and its application in natural freshwater

Researchers developed a method using asymmetrical flow field-flow fractionation (AF4) coupled with multiple detectors to efficiently separate and characterize polystyrene nanoplastics by particle size in freshwater environments, demonstrating its applicability for analysing nanoplastic environmental behaviour in natural freshwater samples.

2025 RSC Advances
Article Tier 2

An optimized multi-technique based analytical platform for identification, characterization and quantification of nanoplastics in water

Researchers developed an analytical platform combining flow fractionation, light scattering, and pyrolysis-GC/MS to simultaneously identify polymer type, measure particle size distribution, and quantify nanoplastics in water samples down to 0.01 ppm, filling a key gap in nanoplastic monitoring tools.

2024 Talanta 16 citations
Article Tier 2

Matrix OverloadingEffects on Size-Resolved Quantificationof Low-Concentration Nanoplastics in Complex Environmental MatricesUsing Asymmetric Flow Field-Flow Fractionation

Researchers developed a size-resolved nanoplastic quantification method using asymmetric flow field-flow fractionation with on-channel preconcentration, identifying and characterizing matrix overloading effects that cause analytical artifacts when measuring nanoplastics in complex environmental water samples.

2025 Figshare
Article Tier 2

An effective solution to simultaneously analyze size, mass and number concentration of polydisperse nanoplastics in a biological matrix: asymmetrical flow field fractionation coupled with a diode array detector and multiangle light scattering

Researchers developed an asymmetrical flow field-flow fractionation method coupled with a diode array detector and multiangle light scattering to simultaneously measure the size, mass, and number concentration of polydisperse nanoplastics in biological matrices, providing a more accurate tool for assessing nanoplastic pollution levels.

2021 RSC Advances 5 citations
Article Tier 2

Matrix Overloading Effects on Size-Resolved Quantification of Low-Concentration Nanoplastics in Complex Environmental Matrices Using Asymmetric Flow Field-Flow Fractionation

Researchers developed a size-resolved method for quantifying nanoplastics in the 20-200 nm range in environmental water samples using asymmetric flow field-flow fractionation. The study identified important analytical artifacts from matrix overloading effects that can occur when measuring low-concentration nanoplastics in complex environmental samples, providing guidance for more accurate quantification methods.

2025 Analytical Chemistry 1 citations
Article Tier 2

Separation and enrichment of nanoplastics in environmental water samples via ultracentrifugation

An ultracentrifugation protocol was developed and validated for separating and concentrating nanoplastics from environmental water samples, enabling detection of particles below 100 nm that are otherwise lost during conventional filtration-based processing, and revealing nanoplastics in river water samples at concentrations not previously quantified.

2021 Water Research 73 citations
Article Tier 2

A novel platform using a regenerable SDS-functionalized membrane with AF4-DAD-MALS for online-operated enrichment and detection of polydisperse nanoplastics in biological samples

This study developed a novel analytical platform combining an SDS-functionalized membrane with asymmetric flow field-flow fractionation to detect and characterize nanoplastics in biological samples. The method enabled online enrichment and size-resolved detection of polydisperse nanoplastics at concentrations relevant to health exposure assessments.

2025 Analytical Methods
Article Tier 2

New Advances and Applications in Field-Flow Fractionation

This review covers field-flow fractionation—a family of separation techniques—and its expanding applications for characterizing nanoparticles, polymers, and complex biological materials. The technology is increasingly used to separate and analyze nanoplastics from environmental and biological samples.

2021 Annual Review of Analytical Chemistry 24 citations
Article Tier 2

Nanoplastic Analysis by Online Coupling of Raman Microscopy and Field-Flow Fractionation Enabled by Optical Tweezers

Researchers developed a new analytical technique for detecting nanoplastics by combining field-flow fractionation with online Raman microspectroscopy, using optical tweezers to trap particles and overcome weak scattering signals. The method successfully identified polymer and inorganic particles ranging from 200 nm to 5 micrometers at concentrations around 1 mg/L.

2020 Analytical Chemistry 151 citations
Article Tier 2

Evaluating theEfficiency of Enhanced Coagulationfor Nanoplastics Removal Using Flow Cytometry

Researchers evaluated the efficiency of enhanced coagulation for removing nanoplastics from water using flow cytometry as a quantification tool, addressing the interconnected challenges of nanoplastic removal and detection in conventional water treatment systems.

2025 Figshare
Article Tier 2

In-house validation of AF4-MALS-UV for polystyrene nanoplastic analysis

Researchers validated an asymmetric flow field-flow fractionation method coupled with multi-angle light scattering and UV detection for simultaneously sizing and quantifying polystyrene nanoplastics from 20 to 200 nm, achieving greater than 90% recovery and detection limits of 15–33 µg/mL across a polydisperse nanoplastic mixture.

2021 Analytical and Bioanalytical Chemistry 27 citations
Article Tier 2

Separate determination of polystyrene nanoplastics and microplastics in water by membrane filtration and gel permeation chromatography-ultraviolet detection analysis

Researchers developed a practical laboratory method to separately measure polystyrene nanoplastics and microplastics in water samples using membrane filtration and a specialized chromatography technique. The method was validated in both environmental water and tap water, confirming the presence of nanoplastics through multiple analytical approaches. This represents an important step forward in the ability to accurately distinguish between different sizes of plastic pollution in drinking and environmental water.

2025 Talanta 4 citations
Article Tier 2

Physicochemical characterization and quantification of nanoplastics: applicability, limitations and complementarity of batch and fractionation methods

Researchers evaluated a suite of techniques for measuring the size, shape, and chemical makeup of nanoplastics — plastic particles smaller than 1 micrometer — and found that no single method works for all sample types, especially when particles vary in size or clump together. Combining multiple complementary techniques is essential for reliable nanoplastic characterization, particularly in complex environmental or biological samples.

2023 Analytical and Bioanalytical Chemistry 56 citations
Article Tier 2

A membrane cascade for size-based separation and concentration of nanoplastics in environmental waters

Researchers developed a cascade system of membrane filters that can separate and concentrate nanoplastics from environmental water samples by size. They demonstrated that the system effectively isolates nanoplastic particles while tracking recovery rates using fluorescent markers. The technology addresses a major challenge in nanoplastic research by providing a reliable method to extract these extremely small particles from water for accurate measurement and analysis.

2025 Separation and Purification Technology 2 citations
Article Tier 2

IntegratingAF4 and Py-GC-MS for Combined Size-ResolvedPolymer-Compositional Analysis of Nanoplastics with Application toWastewater

Researchers developed a novel workflow for nanoplastic characterization in environmental water samples by integrating asymmetric flow field-flow fractionation with multiangle light scattering (AF4-MALS) and pyrolysis-gas chromatography-mass spectrometry (Py-GC-MS) in an offline combination. This approach enables simultaneous size-resolved and polymer-compositional analysis of nanoplastics in wastewater, addressing the lack of standardized methods for this challenging contaminant class.

2025 Figshare
Article Tier 2

Integrating AF4 and Py-GC-MS for Combined Size-Resolved Polymer-Compositional Analysis of Nanoplastics with Application to Wastewater

This study combined asymmetric flow field-flow fractionation with multiangle light scattering and pyrolysis-GC-MS in an offline workflow to simultaneously characterize nanoplastic size distribution (down to ~1 nm) and polymer composition in wastewater, offering a new standard-compatible approach for environmental nanoplastic analysis.

2025 Analytical Chemistry 3 citations
Article Tier 2

Online Coupling of Field-Flow Fractionation with Raman Microspectroscopy Enables the Advanced Study of Nanoplastics Directly in Food

Researchers developed an online coupling of field-flow fractionation with Raman microspectroscopy to enable direct detection and characterisation of nanoplastics in complex food matrices, overcoming limitations of existing methods that require laborious sample preparation.

2025 Analytical Chemistry
Article Tier 2

Characterization of Nanoparticles in Drinking Water Using Field-Flow Fractionation Coupled with Multi-Angle Light Scattering and Inductively Coupled Plasma Mass Spectrometry

Researchers developed methods using field-flow fractionation coupled with multi-angle light scattering and mass spectrometry to characterize nanoparticles in drinking water. The study addresses the lack of standardized techniques for detecting submicrometer particles, including nanoplastics, highlighting the need for better analytical tools to monitor emerging water contaminants.

2024 Water 2 citations
Article Tier 2

Extraction and concentration of nanoplastic particles from aqueous suspensions using functionalized magnetic nanoparticles and a magnetic flow cell

Researchers developed a method using hydrophobic magnetic nanoparticles to capture and concentrate nanoplastics — plastic particles smaller than 1 micrometer — from water samples, achieving recovery rates of 57–85% across different water types including freshwater and seawater. This technique addresses a major gap in nanoplastic research by making it possible to detect and measure these nearly invisible particles in real environmental samples.

2023 Microplastics and Nanoplastics 27 citations
Article Tier 2

Size-classifiable quantification of nanoplastic by rate zonal centrifugation coupled with pyrolysis-gas chromatography-mass spectrometry

Researchers combined rate-zonal centrifugation with pyrolysis-GC-MS to separately quantify nanoplastics of three distinct size classes (100, 300, and 600 nm) in water samples with high recovery rates (81–89%), providing a scalable analytical method for size-resolved environmental nanoplastic monitoring.

2024 Analytica Chimica Acta 6 citations
Article Tier 2

Identification and Quantification of Nanoplastics in Surface Water and Groundwater by Pyrolysis Gas Chromatography–Mass Spectrometry

Researchers developed a method combining ultrafiltration and pyrolysis gas chromatography-mass spectrometry to identify and quantify nanoplastics in surface water and groundwater. The study successfully detected six types of plastic polymers at the nanoscale in environmental water samples, providing much-needed quantitative data on nanoplastic pollution in real-world water sources.

2022 Environmental Science & Technology 210 citations
Article Tier 2

Nanoplastics in aquatic environments: Origin, separation and characterization: Review

This review covers the origins, separation methods, and characterization of nanoplastics in aquatic environments. Nanoplastics (1–100 nm) are particularly concerning because their tiny size gives them a large surface area for adsorbing pollutants and allows them to penetrate biological barriers more easily than larger microplastics.

2023 Tehnika
Article Tier 2

Selective quantification of nanoplastics in environmental matrices by asymmetric flow field-flow fractionation with total organic carbon detection

Researchers developed the first proof-of-principle method hyphenating asymmetric flow field-flow fractionation (AF4) with total organic carbon detection for selective quantification of nanoplastics in environmental matrices, demonstrating improved robustness against dissolved organic matter and clay colloid interference compared to existing approaches.

2021 Chemical Communications 25 citations