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61,005 resultsShowing papers similar to A Comprehensive Narrative Review of Potential Gastrointestinal Adverse Effects From Micro(nano) Plastic Exposure
ClearImpact of micro- and nanoplastics on gastrointestinal diseases: Recent advances
This review summarizes how micro- and nanoplastics can harm the digestive system by causing oxidative stress, inflammation, cell death, and disruption of gut bacteria. These connected pathways can damage the intestinal lining and may contribute to conditions like inflammatory bowel disease and colorectal cancer. The findings highlight the importance of understanding how everyday plastic exposure through food and water could affect gut health over time.
Micro(nano)plastics and their potential impact on human gut health: a narrative review
This narrative review synthesizes evidence on how microplastics and nanoplastics affect the human gut, discussing ingestion routes, gut barrier interactions, microbiome disruption, and potential systemic health effects.
Orally Ingested Micro- and Nano-Plastics: A Hidden Driver of Inflammatory Bowel Disease and Colorectal Cancer.
This review synthesizes evidence linking ingested micro- and nano-plastics to inflammatory bowel disease and colorectal cancer risk, proposing that microplastics act as a hidden driver of gut inflammation in vulnerable populations. The authors argue that intestinal accumulation of microplastics triggers immune and oxidative stress pathways that contribute to disease progression.
[Effect of microand nanoplastics on the gastrointestinal mucosa and intestinal microbiome].
This review examines how micro- and nanoplastics entering through the food chain affect the gastrointestinal tract, finding evidence of disruption to gut mucosal integrity and intestinal microbiome composition, with implications for digestive health and systemic immune function.
Micro(nano)plastics in food system: potential health impacts on human intestinal system.
This review assessed how micro(nano)plastics in the human food system reach the intestine and accumulate in the gut, summarizing evidence that they can alter intestinal barrier function, trigger inflammation, and disrupt the gut microbiome, with implications for long-term digestive health.
Micro(nano)plastics and Their Potential Impact on Human Gut Health: A Narrative Review
This review summarizes research on how micro- and nanoplastics affect the gut, finding that they can damage the intestinal lining, trigger immune responses, and disrupt the balance of beneficial gut bacteria in both cell studies and animal models. Since humans are primarily exposed to microplastics through food and food packaging, understanding these gut effects is essential for assessing the true health risks of plastic pollution.
Microplastics and health hazards: gastrointestinal risk assessment across a multi-species perspective
This review assesses the gastrointestinal health risks of micro- and nanoplastics across multiple species, from aquatic organisms to mammals, examining how these particles interact with the digestive system. Researchers found that microplastics can cause gut inflammation, alter the microbiome, and potentially cross the intestinal barrier into other tissues. The study highlights that understanding effects across species can help predict potential risks to human digestive health.
Micro- and Nanoplastics as Emerging Environmental Materials: GreenChemistry Insights into Gut Microbiota Disruption and Chronic DiseasePathways
Researchers reviewed how micro- and nanoplastics accumulate in the gastrointestinal tract and disrupt gut microbiota composition, finding evidence linking these exposures to reduced microbial diversity, gut barrier dysfunction, systemic inflammation, and potential contributions to chronic diseases including metabolic disorders and neurodegeneration.
Immunotoxicity and intestinal effects of nano- and microplastics: a review of the literature
This review examines the evidence on how nano- and microplastics affect the immune system and intestinal health. The findings suggest that exposure to these particles can disrupt the gut microbiome and impair critical intestinal barrier functions, potentially contributing to the development of chronic inflammatory and immune conditions.
Effect of microplastics and nanoplastics in gastrointestinal tract on gut health: A systematic review.
This systematic review provides the first comprehensive look at how microplastics and nanoplastics affect the human gut using laboratory models. The findings help explain how these tiny particles may damage the digestive tract lining and trigger inflammation, which is important for understanding the health risks of swallowing microplastics in food and water.
Microplastics: An emerging environmental risk factor for gut microbiota dysbiosis and cancer development?
This review examines how microplastics may disrupt the gut microbiome and immune system in ways that could promote cancer development. Evidence from recent studies suggests microplastics can cause chronic inflammation, alter the balance of gut bacteria, and trigger molecular pathways linked to several cancer types including lung, liver, breast, and colon cancer. While more human research is needed, the review highlights a concerning connection between microplastic exposure, gut health, and cancer risk.
Potential effects of MPs and their co-pollutants on human intestinal tract
This review examines how microplastics and their co-pollutants enter and damage the human intestinal tract, summarizing evidence for microplastic-induced gut barrier disruption, microbiota alteration, and systemic translocation to other organs.
Gut microbiota as an emerging target for the health implications of microplastics
This review examines how microplastic exposure disrupts the gut microbiome, finding evidence that microplastics damage intestinal barrier proteins, promote inflammation and oxidative stress, and may drive systemic effects including neurotoxicity and reproductive toxicity through gut-mediated pathways.
Micro- and nano-plastics, intestinal inflammation, and inflammatory bowel disease: A review of the literature
This review summarizes the growing evidence linking micro- and nanoplastic exposure to intestinal inflammation and inflammatory bowel disease (IBD). Studies show these tiny plastic particles can trigger immune responses in the gut, alter the gut microbiome, and worsen intestinal inflammation, though more research using standardized methods is needed to confirm these effects in humans.
The infiltration of microplastics in human systems: Gastrointestinal accumulation and pathogenic impacts
This review focuses on how microplastics accumulate in the human digestive system and what health problems they might cause. The authors explain that people ingest microplastics through food, water, and air, and these particles may trigger inflammation, disrupt gut bacteria, and potentially contribute to gastrointestinal diseases.
Effects of microplastic and engineered nanomaterials on inflammatory bowel disease: A review
This review examines how microplastics and engineered nanomaterials affect people with inflammatory bowel disease, who may be especially vulnerable to these environmental particles. Researchers found that microplastics could worsen intestinal inflammation, while some nanomaterials shifted from mildly harmful to therapeutic effects depending on gut health status. The findings highlight the need for more research on how environmental particles affect people with pre-existing gut conditions.
Effect of microplastics and nanoplastics in gastrointestinal tract on gut health: A systematic review.
This systematic review of 30 in vitro studies found that microplastics and nanoplastics cause size- and concentration-dependent damage to human gastrointestinal cells, including increased oxidative stress, mitochondrial dysfunction, inflammation, and apoptosis. Smaller particles consistently showed greater cellular uptake and biological effects, though chronic low-dose exposure generally produced minimal impacts.
Impacts of microplastics on gut health: Current status and future directions
This systematic review found consistent evidence across mouse, fish, and earthworm models that microplastics disrupt gut microbiota composition, impair intestinal barrier integrity, and trigger gastrointestinal inflammation. The correlation between microplastic exposure and gut health deterioration was statistically significant across all animal models examined.
The role of gut microbiota in MP/NP-induced toxicity
This review summarizes how micro- and nanoplastics disrupt gut bacteria and why that matters for overall health. The tiny plastic particles change the composition and function of the gut microbiome, which can trigger inflammation, weaken the intestinal barrier, and potentially contribute to diseases beyond the gut through the immune and nervous systems.
Molecular insights into physiological impact of micro- and nano-plastics on the digestive system and gut-brain axis
This review evaluates molecular-level evidence on how micro- and nanoplastics affect the digestive system and the gut-brain axis after ingestion through contaminated food and water. The study describes how these particles accumulate in the gastrointestinal tract, liver, and pancreas, causing oxidative stress, gut microbiota disruption, and compromised intestinal barriers, potentially allowing particles to reach the central nervous system and contribute to neuroinflammatory conditions.
Invisible invaders: unveiling the carcinogenic threat of microplastics and nanoplastics in colorectal cancer-a systematic review
This systematic review examines the potential link between microplastics and nanoplastics and colorectal cancer. The research highlights how these tiny particles may contribute to cancer development through mechanisms like chronic inflammation and cellular damage in the gut. While more studies are needed, the findings raise important questions about the long-term consequences of ingesting plastic particles.
The role of microplastics in the pathogenesis of inflammatory bowel diseases
This review of existing research found that tiny plastic particles we eat and drink may contribute to inflammatory bowel diseases like Crohn's disease and ulcerative colitis. The plastic bits can damage the gut lining, cause inflammation, and disrupt the healthy bacteria in our intestines. While more research is needed to confirm the connection, this suggests that reducing plastic pollution could be important for protecting our digestive health.
Microplastics and the gut microbiome: Emerging health concerns and strategies
This review covers how microplastic ingestion affects the gut microbiome, describing mechanisms by which microplastics cause intestinal disorders, disrupt endocrine function, and promote pathogenic bacterial growth, while also noting inhalation and dermal absorption as secondary exposure routes.
Ingested microplastics pose a potentially serious risk to the gastrointestinal microenvironment
This review argues that ingested microplastics pose a serious potential risk to the gastrointestinal microenvironment by disrupting the gut microbiome, irritating the intestinal lining, and potentially carrying toxic additives and adsorbed chemicals into the digestive tract. Given that human microplastic ingestion is now unavoidable, the authors call for urgent research into gastrointestinal health effects.