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Effects of microplastic and engineered nanomaterials on inflammatory bowel disease: A review
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This review examines how microplastics and engineered nanomaterials affect people with inflammatory bowel disease, who may be especially vulnerable to these environmental particles. Researchers found that microplastics could worsen intestinal inflammation, while some nanomaterials shifted from mildly harmful to therapeutic effects depending on gut health status. The findings highlight the need for more research on how environmental particles affect people with pre-existing gut conditions.
Many microplastics and engineered nanomaterials (ENMs) exist in the daily environment. The intestinal impact of these exogenous fine particles on inflammatory bowel disease (IBD) people may be unpredictable. In this paper, we reviewed the recent progress in the effect of microplastics and ENMs on IBD individuals. We also compared and summarized the various roles of microplastics and ENMs in healthy and IBD bodies, including factors such as particle size, particle properties, intestinal microenvironment, interaction with the intestinal barrier, and molecular mechanism. Our literature review showed that microplastics could be accomplices in the development of IBD and could cause severe intestinal inflammation. Moreover, ENMs could elicit diverse exposure outcomes in healthy and IBD bodies. Silicon dioxide nanoparticles (SiO NPs), titanium dioxide nanoparticles (TiO NPs), and graphene oxide (GO) displayed slight to adverse effects that turned into apparent adverse effects, while zinc oxide nanoparticles (ZnO NPs) and silver nanoparticles (Ag NPs) showed a toxic effect that became therapeutic. A deeper understanding of the impact of microplastics and ENMs on the high-risk group was needed, and we proposed several insights into the research priorities and directions.
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Microplastics and inflammatory bowel disease: dissecting the evidence from observational links to potential causal mechanisms
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This review pulls together existing research suggesting that tiny plastic particles we ingest may weaken our gut's protective barrier and disrupt healthy gut bacteria, potentially fueling inflammatory bowel disease. While the link isn't proven yet, it's a reminder that reducing plastic exposure in food and water could matter for long-term gut health.
The role of microplastics in the pathogenesis of inflammatory bowel diseases
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This review of existing research found that tiny plastic particles we eat and drink may contribute to inflammatory bowel diseases like Crohn's disease and ulcerative colitis. The plastic bits can damage the gut lining, cause inflammation, and disrupt the healthy bacteria in our intestines. While more research is needed to confirm the connection, this suggests that reducing plastic pollution could be important for protecting our digestive health.
Micro- and nano-plastics, intestinal inflammation, and inflammatory bowel disease: A review of the literature
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This review summarizes the growing evidence linking micro- and nanoplastic exposure to intestinal inflammation and inflammatory bowel disease (IBD). Studies show these tiny plastic particles can trigger immune responses in the gut, alter the gut microbiome, and worsen intestinal inflammation, though more research using standardized methods is needed to confirm these effects in humans.
Micro- and Nanoplastics: A Paradigm Shift in the Pathogenesis of Inflammatory Bowel Disease
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This review paper summarizes research showing that tiny plastic particles from food and water may contribute to inflammatory bowel disease (IBD), a painful condition affecting the digestive system. Early studies suggest these microscopic plastics can damage the gut lining and trigger inflammation, though more research is needed to prove they directly cause IBD. Since plastic exposure can potentially be reduced, understanding this connection could lead to new ways to prevent or treat digestive diseases.
Analysis of Microplastics in Human Feces Reveals a Correlation between Fecal Microplastics and Inflammatory Bowel Disease Status
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Researchers found higher concentrations and greater diversity of microplastics in fecal samples from inflammatory bowel disease patients compared to healthy controls, suggesting a potential association between microplastic ingestion and gut inflammation, though causality remains to be established.
Research digests by email
When a large batch of papers lands in the Atlas, we read through it and send a short write-up of what stood out.