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61,005 resultsShowing papers similar to Epigenetic Effects of Healthy Foods and Lifestyle Habits from the Southern European Atlantic Diet Pattern: A Narrative Review
ClearEnvironmental Epigenetics and Obesity
This review examines how environmental and dietary factors drive epigenetic changes that contribute to obesity, highlighting the role of nutritional interventions in regulating gene expression and metabolic responses linked to chronic non-communicable diseases.
Evaluation of Primary DNA Damage in Young Healthy Females Based on Their Dietary Preferences
Researchers evaluated primary DNA damage in young healthy females based on dietary preferences, finding that certain dietary patterns were associated with different levels of DNA damage as measured by the comet assay biomarker.
Effect of legacy and emerging pollutants on genome-wide methylation patterns in black hake (Merluccius polli) natural populations
A genome-wide methylation study of marine mussels exposed to heavy metals and microplastics in the wild found that pollutant exposure caused measurable epigenetic changes, demonstrating that DNA methylation patterns can serve as molecular biomarkers of environmental contamination in wild populations.
Epigenetic Mechanisms in Aging: Extrinsic Factors and Gut Microbiome
This review explores how external environmental factors and the gut microbiome influence epigenetic changes associated with aging. Researchers found that gut bacteria can modify host gene expression through histone and DNA modifications, with microbial metabolites playing an underexplored role. The study highlights the need for further research into how environmental exposures, including pollutants, may affect aging through gut-mediated epigenetic mechanisms.
A Connection Between the Gut Microbiome and Epigenetic Modification in Age-Related Cancer: A Narrative Review
This review explores how age-related changes in the gut microbiome can influence cancer development through epigenetic modifications like DNA methylation and histone alterations. Researchers found that the gut microbiome plays a dual role, both protecting against and potentially contributing to cancer susceptibility as people age. The study suggests that targeted interventions to maintain a healthy gut microbiome could be a strategy for reducing age-related cancer risk.
DNA Methylation Biomarkers-Based Human Age Prediction Using Machine Learning
A machine learning model was developed to predict biological age from DNA methylation biomarkers, demonstrating performance applicable to both healthy individuals and disease cohorts. The study contributes to the growing field of epigenetic aging clocks with potential applications in assessing environmental health impacts and disease risk.
Healthful Diet and Nutritional Food as a Preventive and Interventional Paradigm in the Face of Microplastic and Nanoplastic Crisis
This review examines dietary patterns and nutritional interventions as potential strategies to reduce health risks from microplastic and nanoplastic exposure, discussing how antioxidant-rich foods and specific nutrients may mitigate inflammation and oxidative stress triggered by MNP ingestion.
DNA methylation differs extensively between strains of the same geographical origin and changes with age in Daphnia magna
Researchers examined DNA methylation patterns across strains of the same geographical origin, finding methylated cytosines concentrated in early gene exons in a directed non-random pattern, and observed no effect of caloric restriction on methylation despite established impacts on phenotype and gene expression.
A systematic review of associations between the environment, DNA methylation, and cognition
This systematic review of 14 studies found that DNA methylation statistically mediates the association between environmental exposures (air pollution, heavy metals, pesticides) and cognitive outcomes in 10 of the 14 studies. While the review focuses broadly on environmental epigenetics rather than microplastics specifically, it provides a framework for understanding how pollutant exposures may drive neurodegenerative disease through epigenetic mechanisms.
Investigating the Epigenetic Effects of Polystyrene Nanoplastic Exposure in Bluegill (Lepomis macrochirus) Epithelial Cells Using Methylation-Sensitive AFLPs
Researchers exposed bluegill fish cells to polystyrene nanoplastics and examined whether the exposure caused changes in DNA methylation, a type of genetic modification that can alter how genes function. They found that nanoplastic exposure did cause methylation changes across the genome, but the effect was not dependent on dose or exposure time -- simply being exposed to nanoplastics was enough to trigger the changes. The findings suggest that even low-level nanoplastic exposure could have epigenetic effects on aquatic organisms.
High fish intake rich in n-3 polyunsaturated fatty acids reduces cardiovascular disease incidence in healthy adults: The ATTICA cohort study (2002-2022)
Researchers found that high fish intake rich in n-3 polyunsaturated fatty acids was associated with reduced cardiovascular disease incidence over 10- and 20-year follow-up periods in healthy Greek adults from the ATTICA cohort study.
Systematic Review: Efek Nanoplastik terhadap Metilasi DNA pada Manusia
This systematic review, written in Indonesian, examines how nanoplastics may affect DNA methylation in humans — a process that controls which genes are turned on or off. Changes in DNA methylation can influence disease risk, including cancer. The review highlights an important but understudied pathway through which tiny plastic particles could affect human health at the genetic level.
Nutritional Modulation of Epigenetic Changes Induced by Mycotoxins: A Biochemical Perspective for At-Risk Populations in Africa
This review examines how nutritional factors can modulate the epigenetic changes caused by mycotoxin exposure in at-risk populations in Sub-Saharan Africa. The study explores how nutrients like folate, zinc, and selenium may counteract harmful DNA methylation and histone modifications triggered by common food contaminants such as aflatoxin B1. While not focused on microplastics directly, the research provides insights into how nutrition can influence the body's response to environmental contaminants.
Micro(nano)plastics in the brain: Epigenetic perturbations in progression to neurodegenerative diseases.
This review examined how micro(nano)plastics (MNPs) accumulate in the brain and induce epigenetic changes—including DNA methylation and histone modification—that may drive the progression of neurodegenerative diseases. MNPs were found to disrupt neuronal homeostasis through multiple epigenetic mechanisms after crossing the blood-brain barrier.
Nanoplastics as Epigenetic Disruptors: A Biochemical Review of Environmental Pollutants and Gene Regulation
This biochemical review examined how nanoplastics disrupt epigenetic regulation, focusing on their ability to alter DNA methylation patterns, histone modifications, and non-coding RNA expression. The authors argued that nanoplastic-induced epigenetic changes could have lasting developmental and health consequences, especially during vulnerable life stages.
Effect of Early-Life Exposure of Polystyrene Microplastics on Behavior and DNA Methylation in Later Life Stage of Zebrafish
Researchers exposed zebrafish embryos to polystyrene microplastics during early development and then assessed neurobehavioral effects later in life. The study found that early-life microplastic exposure caused lasting changes in behavior and DNA methylation patterns, suggesting that developmental exposure to microplastics may have long-term epigenetic consequences on neurodevelopment.
Cognitive and functional resilience as markers of longevity and successful ageing
This systematic literature review examined cognitive and functional resilience as markers of longevity and successful aging, synthesizing evidence on how these capacities are influenced by genetics, environment, and lifestyle and can predict quality of life in older adults.
Epigenetic Modifications and Gene Expression Alterations in Plants Exposed to Nanomaterials and Nanoplastics: The Role of MicroRNAs, lncRNAs and DNA Methylation
This review examines how nanomaterials and nanoplastics alter plant gene expression through epigenetic mechanisms, focusing on changes in microRNA, long non-coding RNA, and DNA methylation patterns that could disrupt normal plant development and stress responses.
The Presence of Micro- and Nanoplastics in Food and the Estimation of the Amount Consumed Depending on Dietary Patterns
This review examines how much micro- and nanoplastic contamination is present in different foods, from fruits and vegetables to seafood, meat, and dairy. For the first time, it compared microplastic intake across three common European diets and found that vegetarian diets actually resulted in the highest intake due to large amounts of fruits, vegetables, and legumes. The Mediterranean diet offered the best balance of health benefits and lower microplastic consumption.
Changes in global methylation patterns of Mytilus galloprovincialis exposed to microplastics
Researchers found that exposing mussels to polystyrene microplastics caused changes in their DNA methylation patterns, an epigenetic modification that controls how genes are turned on and off. Higher microplastic concentrations led to greater loss of methylation, and similar patterns were seen in wild mussels from polluted areas. This suggests microplastics could affect organisms at the genetic regulation level, potentially influencing metabolism and cell division.
Exploring the epigenome to identify biological links between the urban environment and neurodegenerative disease: an evidence review
This review examines how environmental factors commonly found in cities, such as air pollution and traffic-related contaminants, may contribute to neurodegenerative diseases through changes in gene regulation known as epigenetic modifications. Researchers found that pollutant exposures can alter DNA methylation and other epigenetic markers linked to brain health, though the evidence base remains limited. The study suggests that studying these molecular-level changes could help explain why urban living is associated with higher rates of cognitive decline.
Application of transcriptomic profiling to investigate the toxicity mechanisms caused by dietary exposure of nanoplastics in fish
Researchers used transcriptomic profiling to evaluate the impact of dietary nanoplastic exposure on European sea bass, finding changes in gene expression in intestinal tissue after 21 days of feeding with polystyrene nanoparticle-containing food. The study suggests that while no significant changes were observed in enzymatic stress markers, nanoplastics may trigger subtle molecular-level responses in the fish gut.
Microplastic exposure and the role of dietary patterns in school-aged children
Scientists found tiny plastic particles in the urine of over 90% of 10-year-old children they tested, showing that microplastics are widespread in our bodies. Children who followed healthier eating patterns similar to the Mediterranean diet (lots of fruits, vegetables, and fish) had lower levels of some types of plastic particles in their urine. This suggests that eating healthier foods might help reduce our exposure to harmful microplastics, though more research is needed to understand the long-term health effects.
Gut microbiota: an ideal biomarker and intervention strategy for aging
Not relevant to microplastics — this review explores how gut microbiome composition can serve as a biomarker for aging and a target for anti-aging interventions in humans, without addressing plastic pollution.