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Epigenetic Effects of Healthy Foods and Lifestyle Habits from the Southern European Atlantic Diet Pattern: A Narrative Review

Advances in Nutrition 2022 55 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count. Score: 55 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.
Paula M. Lorenzo, Andrea G. Izquierdo, Gemma Rodríguez-Carnero, Antía Fernández‐Pombo, Alba Iglesias, Marcos C. Carreira, Cristina Tejera Pérez, Diego Bellido, Miguel Ángel Martínez Olmos, Rosaura Leis, Felipe F. Casanueva, Ana B. Crujeiras

Summary

Researchers reviewed how the Southern European Atlantic diet — rich in fish, vegetables, and minimally processed foods — influences epigenetic markers such as DNA methylation and microRNA expression, proposing that this dietary pattern promotes healthy aging by modulating gene expression through nutrient-driven epigenetic mechanisms.

Recent scientific evidence has shown the importance of diet and lifestyle habits for the proper functioning of the human body. A balanced and healthy diet, physical activity, and psychological well-being have a direct beneficial effect on health and can have a crucial role in the development and prognosis of certain diseases. The Southern European Atlantic diet, also named the Atlantic diet, is a unique dietary pattern that occurs in regions that present higher life expectancy, suggesting that this specific dietary pattern is associated with positive health effects. In fact, it is enriched with nutrients of high biological value, which, together with its cooking methods, physical activity promotion, reduction in carbon footprint, and promoting of family meals, promote these positive effects on health. The latest scientific advances in the field of nutri-epigenetics have revealed that epigenetic markers associated with food or nutrients and environmental factors modulate gene expression and, therefore, are involved with both health and disease. Thus, in this review, we evaluated the main aspects that define the Southern European Atlantic diet and the potential epigenetic changes associated with them based on recent studies regarding the main components of these dietary patterns. In conclusion, based on the information existing in the literature, we postulate that the Southern European Atlantic diet could promote healthy aging by means of epigenetic mechanisms. This review highlights the necessity of performing longitudinal studies to demonstrate this proposal.

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