We can't find the internet
Attempting to reconnect
Something went wrong!
Hang in there while we get back on track
Papers
61,005 resultsShowing papers similar to Toxic Effect of Combined Exposure of Microplastics and Copper on Goldfish (Carassius auratus): Insight from Oxidative Stress, Inflammation, Apoptosis and Autophagy in Hepatopancreas and Intestine
ClearCombined effects of polystyrene microplastics and copper on antioxidant capacity, immune response and intestinal microbiota of Nile tilapia (Oreochromis niloticus)
Researchers examined the combined effects of polystyrene microplastics and copper on Nile tilapia and found that co-exposure increased copper accumulation in the liver and caused tissue damage in multiple organs. High concentrations of both contaminants together triggered oxidative stress, inflammation, and shifts in intestinal microbial communities. The study suggests that microplastics can worsen the toxic effects of heavy metals on freshwater fish.
“Copper-loaded microplastics unleash endoplasmic reticulum stress-driven liver apoptosis in fish Channa punctatus”
Researchers found that PVC microplastics loaded with copper caused severe liver damage in fish through a process called endoplasmic reticulum stress, which triggers cell death. The combined exposure to microplastics and copper was more harmful than either pollutant alone. This study demonstrates how microplastics can act as carriers for toxic metals, amplifying their harmful effects on organ health.
Combined effects of microplastics and copper on antioxidant capacity, gut microbiome, and metabolomics of Pseudorasbora parva
Researchers studied the combined effects of microplastics and copper on the freshwater fish Pseudorasbora parva, examining antioxidant capacity, gut microbiota, and metabolic responses. They found that the presence of microplastics alongside copper actually reduced copper accumulation in tissues and lessened oxidative damage compared to copper exposure alone. The study suggests that while microplastics can alter the toxicity profile of metals in fish, the interactions are complex and involve metabolic adjustments that balance cellular repair and energy expenditure.
Combined effects of microplastics and copper on oxidative responses in zebrafish (Danio rerio)
Researchers exposed zebrafish (Danio rerio) to microplastics (10 µg/L) and copper (45 µg/L) individually and in combination, finding that fish exposed to both stressors simultaneously exhibited higher oxidative stress across multiple body organs than those exposed to either contaminant alone.
The Combined Effect of Copper Nanoparticles and Microplastics on Transcripts Involved in Oxidative Stress Pathway in Rainbow Trout (Oncorhynchus Mykiss) Hepatocytes
Primary rainbow trout hepatocytes were exposed to copper nanoparticles, microplastics, and their combination for 48 hours, finding that both dissolved copper and copper nanoparticles upregulated antioxidant enzyme transcripts while microplastics alone had minimal effect. Co-exposure to nanoparticles and microplastics did not significantly alter the oxidative stress response beyond nanoparticle effects alone.
Histopathological damage and stress‐ and immune‐related genes' expression in the intestine of common carp, Cyprinus carpio exposed to copper and polyvinyl chloride microparticle
Researchers examined the combined effects of copper and PVC microplastics on common carp intestines, finding that co-exposure caused greater histopathological damage and altered stress- and immune-related gene expression compared to either contaminant alone.
First evidence of CuPANotic cell death in fish gut upon environmentally relevant co-exposure to Copper and PVC microplastics
Researchers exposed zebrafish to copper and PVC microplastics at environmentally relevant concentrations and found for the first time that the combination triggers CuPANoptosis — a novel cell death pathway integrating cuproptosis and PANoptosis — with PVC increasing gut copper load by 1.6–1.9-fold.
Hepatic transcriptomic and histopathological responses of common carp, Cyprinus carpio, to copper and microplastic exposure
Researchers investigated how PVC microplastics interact with copper exposure in common carp over 14 days. They found that the microplastic particles acted as a vector for copper, increasing its accumulation in the liver and worsening tissue damage beyond what either pollutant caused alone. The study suggests that microplastics can amplify the toxic effects of heavy metals in freshwater fish.
Microplastics and copper effects on the neotropical teleost Prochilodus lineatus: Is there any interaction?
Researchers exposed the neotropical fish Prochilodus lineatus to polyethylene microplastics and copper separately and together, finding that microplastics alone caused oxidative stress and genotoxic effects, while combined exposure with copper did not consistently amplify harm compared to either stressor alone.
Oxidative stress, apoptosis and serotonergic system changes in zebrafish (Danio rerio) gills after long-term exposure to microplastics and copper
Researchers exposed adult zebrafish to microplastics and copper for 30 days and examined the effects on their gill tissue. They found that the combination caused greater oxidative stress, increased cell death, and disrupted the serotonin signaling system in gills more than either pollutant alone. The study demonstrates that microplastics can amplify the toxic effects of heavy metals on fish respiratory organs.
Long-term effects of individual and combined exposure to microplastics and copper in zebrafish hypothalamic-pituitary-gonadal axis – A multi-biomarker evaluation
This study exposed zebrafish to microplastics, copper, and both combined for 30 days and examined effects on their reproductive system. The combination of microplastics and copper caused greater hormonal disruption and oxidative stress than either pollutant alone, affecting genes that control reproduction in both male and female fish. These findings suggest that microplastics interacting with metal pollution in waterways could compound reproductive harm in aquatic organisms and potentially in humans who consume contaminated fish.
Toxic effects of polystyrene microbeads and benzo[α]pyrene on bioaccumulation, antioxidant response, and cell damage in goldfish Carassius auratus
Researchers exposed goldfish to polystyrene microbeads and benzo[a]pyrene, both individually and in combination, to assess their toxic effects over 120 hours. They found that combined exposure significantly increased oxidative stress, liver damage, and cell death compared to single-compound exposure. The study suggests that microplastics can act as carriers for harmful chemicals, amplifying their toxic impact on aquatic organisms.
Single and Combined Effects of Microplastics and Cadmium on the Cadmium Accumulation and Biochemical and Immunity of Channa argus
Researchers investigated the single and combined effects of microplastics and cadmium on juvenile snakehead fish, finding that co-exposure caused greater tissue damage, oxidative stress, and immune disruption than either pollutant alone.
The impact of combined exposure to triphenyltin and microplastics on the oxidative stress, energy metabolism, and digestive function of common carp (Cyprinus carpio)
Exposing common carp to triphenyltin and microplastics individually and in combination found that combined exposure caused greater oxidative stress, disrupted energy metabolism more severely, and more strongly impaired digestive enzyme activity than either pollutant alone.
Combined effects of copper and microplastics on physiological parameters of Tubastrea aurea corals
Combined exposure of the azooxanthellate coral Tubastrea aurea to copper ions and polystyrene microplastics produced synergistic toxicity, reducing photosynthetic activity and elevating oxidative stress markers more than either pollutant alone, suggesting compounding risks in metal-contaminated coastal waters.
Toxicity of microplastics and copper, alone or combined, in blackspot seabream (Pagellus bogaraveo) larvae
Researchers examined the toxicity of microplastics and copper, alone and combined, on blackspot seabream larvae, finding that microplastic-copper mixtures can alter biochemical biomarkers and gene expression related to oxidative stress and immune response in developing fish.
The impact of microplastics and copper on sex ratio and oxidative stress: analysis in zebrafish intestine, gonad and brain
Researchers exposed zebrafish embryos to copper, polyethylene, and polystyrene microplastics individually and in combination, finding that copper caused high mortality, PE alone induced a feminization trend, and co-exposure amplified adverse effects on sex differentiation and antioxidant enzyme activity.
Single and combined effects of CuSO4 and polyethylene microplastics on biochemical endpoints and physiological impacts on the narrow-clawed crayfish Pontastacus leptodactylus
Researchers exposed freshwater crayfish to polyethylene microplastics and copper sulfate, both alone and together, for 28 days. The combination caused worse effects than either pollutant alone, including liver damage, immune suppression, and increased oxidative stress. This suggests microplastics can amplify the harmful effects of other environmental pollutants in aquatic food sources.
Copper and Microplastic Exposure Affects the Gill Gene Expression of Common Carp During Saltwater Challenge
This study examined how combined copper and microplastic exposure affects gill gene expression in common carp, finding synergistic stress responses including upregulation of genes involved in oxidative stress defense and immune function.
Multi‐Biomarkers' Responses in Gills of Oreochromis niloticus Exposed to Glyphosate and Polyethylene Microplastic, Isolated and in Mixture
Researchers exposed tilapia fish to polyethylene microplastics and the herbicide glyphosate, both alone and in combination, and examined gill tissue for signs of damage. They found that the mixture of both contaminants caused more severe oxidative stress and tissue damage than either pollutant alone. The study suggests that microplastics and agricultural chemicals may interact in waterways to amplify harmful effects on fish health.
Micro-polystyrene plastic and benzo[α]pyrene exposure affects the endocrine system and causes physiological stress in Carassius auratus
Researchers found that combined exposure to polystyrene microplastics and benzo[a]pyrene caused significantly greater endocrine disruption, oxidative stress, and DNA damage in goldfish than either pollutant alone, with effects intensifying through the hypothalamus-pituitary-interrenal axis.
Single and combined acute and subchronic toxic effects of microplastics and copper in zebrafish (Danio rerio) early life stages
Researchers exposed zebrafish embryos and larvae to microplastics, copper, and their combinations to assess individual and combined toxic effects. They found that microplastics alone caused limited harm, but when combined with copper, the mixture produced altered biochemical responses and changes in gene expression. The study suggests that microplastics can modify the toxicity of heavy metals in aquatic organisms during early development.
Isolated and combined toxicity of PVC microplastics and copper on Pinctada fucata martensii: Immune, oxidative, and metabolomics insights
Researchers studied the individual and combined toxic effects of PVC microplastics and copper on pearl oysters over 13 days. They found that combined exposure caused more severe immune suppression, oxidative damage, and metabolic disruption than either pollutant alone. The study demonstrates that microplastics and heavy metals can interact to amplify their harmful effects on marine organisms.
Polystyrene microplastics (PS-MPs) harness copper presence and promote impairments in early zebrafish (Danio rerio) larvae: Developmental, biochemical, transcriptomic approaches and nontargeted metabolomics approaches
This zebrafish study found that polystyrene microplastics combined with copper produced worse toxic effects than either pollutant alone, causing developmental problems, oxidative stress, immune disruption, and nerve damage in larvae. The combination also disrupted the fish's metabolism in ways that neither pollutant caused independently. This is concerning because microplastics readily absorb heavy metals like copper in the environment, meaning organisms are often exposed to both together.