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Papers
61,005 resultsShowing papers similar to Integrative Proteomics and Transcriptomics Profiles of the Oviduct Reveal the Prolificacy-Related Candidate Biomarkers of Goats (Capra hircus) in Estrous Periods
ClearTranscriptomic Analysis of the Developing Testis and Spermatogenesis in Qianbei Ma Goats
Researchers used RNA sequencing to characterize testicular development and spermatogenesis across three age stages in Qianbei Ma goats, identifying nearly 14,000 differentially expressed genes between immature and sexually mature stages involved in reproduction and ion transport pathways.
Transcriptome Profiling of Developing Testes and Spermatogenesis in the Qianbei Ma Goat
This paper is not relevant to microplastics research — it uses RNA sequencing to profile gene expression changes during testis development and spermatogenesis in Qianbei Ma goats at different stages of maturity.
The Physiology of Reproduction – Quo vadis?
This review argues that reproductive physiology remains poorly understood at the systems level, with gamete production and gonadal hormone dynamics reflecting complex, redundant informational networks whose full quantitative and developmental dimensions — and vulnerability to environmental disruptors — are still largely uncharted.
A single-cell atlas of the single versus multiple parous Hu Sheep ovary
This is a sheep reproductive biology study using single-cell RNA sequencing to investigate differences in ovarian gene expression between high- and low-fertility ewes; it is not a microplastics research paper.
Single-cell sequencing reveals the reproductive variations between primiparous and multiparous Hu ewes
Researchers used single-cell sequencing to compare reproductive differences between first-time and experienced mother Hu ewes. The study identified key differences in gene expression within granulosa cells, suggesting these cells play a critical role in determining reproductive capacity. Several specific genes were highlighted as important regulators of follicular development and overall fecundity in sheep.
Single-cell sequencing reveals the reproductive variations between primiparous and multiparous Hu ewes
This paper is not about microplastics; it uses single-cell sequencing of ovarian tissue to investigate genetic mechanisms driving litter size differences between high- and low-reproductive Hu sheep ewes.
Integration of Non-Coding RNA and mRNA Profiles Reveals the Mechanisms of Rumen Development Induced by Different Types of Diet in Calves
Researchers used integrated non-coding RNA and mRNA profiling to reveal molecular mechanisms underlying rumen development in calves fed different diet types, identifying regulatory networks that influence gastrointestinal maturation.
Comparative transcriptomic analysis of gonadal development and renewal in the ovoviviparous black rockfish (Sebastes schlegelii)
Comparative transcriptomic analysis of black rockfish gonads revealed that intercellular interaction, cytoskeletal regulation, and metabolite biosynthesis pathways are crucial in testis development and spermatogenesis in this ovoviviparous species.
Exposição De Microplásticos E Nanoplásticos Ao Tecido Ovariano: Uma Revisão Integrativa
This integrative review examines the impact of micro- and nanoplastics on female ovarian tissue, synthesizing animal model studies showing damage to follicular structures, increased oxidative stress, and disrupted reproductive hormone signaling.
199 Nanoplastics are incorporated by the bovine cumulus–oocyte complex and form a potential treat for oocyte competence
Nanoplastics were found to be taken up by bovine cumulus-oocyte complexes — the cellular unit surrounding an egg — raising concern that nanoplastic contamination of reproductive tissues could compromise egg quality and fertilisation. This conference abstract provides early experimental evidence linking nanoplastic exposure to oocyte competence, with implications for understanding plastic-related reproductive risks across mammals.
The emerging risk of microplastics and nanoplastics on the microstructure and function of reproductive organs in mammals: A systematic review of preclinical evidence
Preclinical evidence from 12 studies shows micro- and nanoplastics accumulate in mammalian gonads, causing dose-dependent damage including seminiferous degeneration, sperm malformation, reduced follicular growth, and impaired hormone levels through pro-oxidant and pro-inflammatory mechanisms.
Microplastics are present in women’s and cows’ follicular fluid and polystyrene microplastics compromise bovine oocyte function in vitro
Researchers detected microplastics in both women's and cows' follicular fluid for the first time, and showed that polystyrene microplastics impair bovine oocyte function in vitro, raising concern that environmental microplastic exposure may be contributing to declining reproductive health.
Application of Ultrasonic Intelligent Imaging in L-Selectin Regulating Embryo Implantation in Mongolian Sheep Endometrium
Researchers used B-mode ultrasonic imaging to observe early embryonic development in Mongolian sheep and investigated the role of L-selectin in regulating the embryo implantation process in the endometrium, demonstrating the application of ultrasonic intelligent imaging in livestock reproductive research.
Transcriptome-wide m6A profiling reveals mRNA post-transcriptional modification of boar sperm during cryopreservation
Researchers mapped chemical modifications (m6A tags) on messenger RNA in boar sperm during freeze preservation for the first time, finding these epigenetic marks are linked to sperm motility and cell survival — offering new insight into why sperm quality declines during cryopreservation.
Reproductive toxicity and related mechanisms of micro(nano)plastics in terrestrial mammals: Review of current evidence.
This review of terrestrial mammal studies found that micro- and nanoplastics induce reproductive toxicity through oxidative stress, inflammation, endocrine disruption, and DNA damage, affecting both male and female fertility. In males, effects include blood-testis barrier disruption and impaired spermatogenesis, while females show compromised oocyte maturation, ovarian fibrosis, and diminished ovarian reserve, with particles also capable of crossing the maternal-fetal interface.
Exposição De Microplásticos E Nanoplásticos Ao Tecido Ovariano: Uma Revisão Integrativa
This integrative review (in Portuguese) examines published evidence on the effects of micro- and nanoplastic exposure on female ovarian tissue morphology, finding disrupted folliculogenesis, oxidative stress, and hormonal interference reported across animal model studies.
Microplastics are present in women’s and cows’ follicular fluid and polystyrene microplastics compromise bovine oocyte function in vitro
Researchers detected microplastics in follicular fluid from both women and cows and showed that polystyrene microplastics disrupt oocyte development, providing the first evidence that microplastics can penetrate reproductive barriers and potentially contribute to the global decline in fertility.
Bibliometric and visual analysis of blood-testis barrier research
This bibliometric analysis of 942 publications on the blood-testis barrier identified key research themes, prolific authors, and emerging frontiers in the field from its inception through recent years. The analysis highlighted growing research into microRNA regulation of barrier integrity and environmental toxicant impacts on Sertoli cell function as future hotspots.
Microplastics are present in women’s and cows’ follicular fluid and polystyrene microplastics compromise bovine oocyte function in vitro
Researchers detected microplastics in the follicular fluid of both women and cows, marking one of the first studies to find these particles in reproductive tissues. In laboratory tests, polystyrene microplastics impaired bovine egg cell function at concentrations comparable to what was found in the follicular fluid. The findings raise questions about whether microplastic exposure could be a contributing factor in the widespread declines in reproductive health observed in recent decades.
Evaluation of the effect of Toxoplasma gonodii on some reproductive hormones in females
Researchers investigated the effects of Toxoplasma gondii infection on reproductive hormones in females, examining how this common parasitic disease — transmitted through undercooked meat, unwashed produce, and cat feces — may affect hormonal balance and reproductive outcomes.
Concerning influences of micro/nano plastics on female reproductive health: focusing on cellular and molecular pathways from animal models to human studies
This review summarizes research showing that micro- and nanoplastics can harm the female reproductive system in multiple ways, from reducing ovarian reserves and disrupting hormone balance to accumulating in the placenta and breast milk. Animal studies show these particles trigger oxidative stress and inflammation in reproductive tissues, and human studies have confirmed their presence in placental tissue and infant feces, raising concerns about effects on fertility and fetal development.
Impacts of Microplastic Debris on the Reproductive Health and Gestational Period Variability in Orcinus orca: A Comprehensive Review
This companion paper examined reproductive health impacts of microplastic debris with a focus on specific mechanisms linking plastic exposure to hormonal disruption and impaired fertility across multiple animal taxa. The review synthesizes emerging evidence to guide future experimental and epidemiological research.
Analyzing the toxicological effects of PET-MPs on male infertility: Insights from network toxicology, mendelian randomization, and transcriptomics
Using network toxicology, Mendelian randomisation, and transcriptomic analysis, researchers identified mechanisms by which PET microplastics may impair male fertility, linking shared gene targets to testicular oxidative stress, hormonal disruption, and spermatogenesis interference. The multi-evidence approach strengthens the case for a causal role of PET-MP exposure in male infertility.
Microplastics in Small Ruminants II
Researchers examined 100 fecal samples from goats in Manabí Province, Ecuador, finding microplastic contamination in all samples and identifying the specific plastic types using two laboratory processing methods.