We can't find the internet
Attempting to reconnect
Something went wrong!
Hang in there while we get back on track
Papers
20 resultsShowing papers similar to Combined Omics Analysis Further Unveils the Specific Role of Butyrate in Promoting Growth in Early-Weaning Animals
ClearIntegration of Non-Coding RNA and mRNA Profiles Reveals the Mechanisms of Rumen Development Induced by Different Types of Diet in Calves
Researchers used integrated non-coding RNA and mRNA profiling to reveal molecular mechanisms underlying rumen development in calves fed different diet types, identifying regulatory networks that influence gastrointestinal maturation.
Carvacrol attenuated lipopolysaccharide-induced intestinal injury by down-regulating TLRs gene expression and regulating the gut microbiota in rabbit
Researchers tested whether carvacrol, a natural plant compound found in oregano and thyme, could protect the intestines of rabbits challenged with a bacterial toxin (lipopolysaccharide), finding it reduced inflammation, improved gut lining structure, and restored healthier gut bacteria communities. These results suggest carvacrol could be a useful dietary supplement for protecting intestinal health in rabbit farming.
Sodium acetate/sodium butyrate alleviates lipopolysaccharide-induced diarrhea in mice via regulating the gut microbiota, inflammatory cytokines, antioxidant levels, and NLRP3/Caspase-1 signaling
Researchers found that sodium acetate and sodium butyrate supplementation alleviated lipopolysaccharide-induced diarrhea in mice by restoring gut microbiota balance, reducing inflammatory cytokines, enhancing antioxidant levels, and inhibiting the NLRP3/Caspase-1 signaling pathway.
Exposure to polyethylene microplastics alters immature gut microbiome in an infant in vitro gut model
Researchers used an artificial infant gut model to study how chronic exposure to polyethylene microplastics affects the developing intestinal microbiome. They found that microplastics shifted gut microbial composition, increasing the abundance of potentially harmful bacteria such as Enterobacteriaceae while decreasing beneficial butyrate production. The study suggests that microplastic ingestion may disrupt the gut microbiome of infants, though no significant damage to the intestinal barrier was observed.
Reduced Glutathione Promoted Growth Performance by Improving the Jejunal Barrier, Antioxidant Function, and Altering Proteomics of Weaned Piglets
A study of 180 weaned piglets showed that adding reduced glutathione to their diet improved growth, strengthened the intestinal barrier, and boosted antioxidant defenses in the gut. These findings suggest that glutathione supplementation could serve as a potential alternative to antibiotics for supporting young animal health during the stressful weaning period.
Differential Impacts of Environmentally Relevant Microplastics on Gut Barrier Integrity in Mice Fed High-Fat Diet Versus Normal Chow Diet
Researchers found that the impact of microplastics on gut barrier integrity differs significantly depending on diet, with mice fed high-fat diets showing different responses than those on normal diets. The gut microbiome and its metabolites, particularly the short-chain fatty acid butyrate, appear to play a critical role in mediating these effects. The study highlights the importance of considering dietary patterns when evaluating how microplastics affect digestive health.
The Effect of Dietary Supplementation with Zinc Amino Acids on Immunity, Antioxidant Capacity, and Gut Microbiota Composition in Calves
Researchers found that dietary supplementation with zinc amino acids improved immunity, antioxidant capacity, and beneficial gut microbiota composition in calves, with effects varying by zinc concentration in the diet.
Postbiotic Sodium Butyrate Mitigates Hypertension and Kidney Dysfunction in Juvenile Rats Exposed to Microplastics
This study reports that sodium butyrate, a postbiotic compound, mitigated microplastic-induced hypertension and kidney dysfunction in juvenile rats by reducing oxidative stress, modulating the gut microbiota, and elevating butyric acid levels.
Mechanism of Mulberry Leaves and Black Sesame in Alleviating Slow Transit Constipation Revealed by Multi-Omics Analysis
Researchers examined how mulberry leaves and black sesame alleviate slow transit constipation in a mouse model, measuring gut motility, microbiota composition, and intestinal gene expression. Both dietary interventions increased beneficial bacteria, enhanced gut peristalsis, and upregulated genes associated with intestinal motility, supporting their traditional use for digestive health.
Establishment of a Long-Term Germ-Free Medaka Model Reveals Microbiota-Dependent Regulation of Growth, Immunity, and Metabolism
Scientists created germ-free fish (with no gut bacteria) to study how the microbes in our intestines affect our health. They found that fish without gut bacteria had stunted growth, weaker immune systems, and metabolism problems, but giving them beneficial compounds from healthy gut bacteria helped partially fix these issues. This research helps us better understand why having healthy gut bacteria is so important for proper growth, immunity, and overall health in humans.
Causal relationship between gut microbiota and gastrointestinal diseases: a mendelian randomization study
This Mendelian randomization study found genetic evidence supporting a causal relationship between specific gut microbiota compositions and gastrointestinal diseases. The findings suggest that microbiome-related interventions, including microbiome-dependent metabolites, could potentially be developed to treat or manage gastrointestinal conditions.
Gut microbiota remodeling drived by dietary millet protein prevents the metabolic syndrome
Researchers found that millet bran protein extract prevented metabolic syndrome in high-fat diet mice by remodeling gut microbiota and reducing obesity, chronic inflammation, and insulin resistance. The protective effects were linked to specific gut microbial metabolites influenced by dietary millet protein.
Carvacrol attenuated lipopolysaccharide-induced intestinal injury by down-regulating TLRs gene expression and regulating the gut microbiota in rabbit
This study examined how carvacrol (a natural plant compound) reduces intestinal inflammation and protects gut microbiota in rabbits challenged with bacterial toxins. Understanding how the gut microbiome responds to different stressors provides context for research on microplastic effects on intestinal health.
Transcriptome Analysis Reveals the Genes Involved in Bifidobacterium Longum FGSZY16M3 Biofilm Formation
Scientists analyzed gene expression in a beneficial gut bacterium during biofilm formation, identifying key genetic networks involved. This microbiome research is relevant context for understanding how microplastics, which can disrupt gut bacterial communities, may affect the beneficial bacteria that protect digestive health.
Socializing Models During Lactation Alter Colonic Mucosal Gene Expression and Fecal Microbiota of Growing Piglets
Researchers investigated how intermittent or continuous social contact with neighboring litters during lactation affects piglet gut health, using RNA sequencing and 16S rRNA microbiome analysis to show that enriched social environments alter colonic mucosal gene expression and fecal microbiota composition in growing piglets.
Gut Microbiome and Small RNA Integrative-Omic Perspective of Meconium and Milk-FED Infant Stool Samples
Characterization of bacteriome, virome, and smallRNome in infant meconium and stool samples found that the gut environment changes rapidly after birth with the bacteriome, virome, and small RNA profiles all differing between meconium and milk-fed infant stool, suggesting transkingdom interactions shape early gut colonization.
Effects of kudzu vine ( Pueraria lobata ) on the intestinal microflora and volatile fatty acids in meat rabbits
Researchers investigated how kudzu vine (Pueraria lobata) supplementation affects intestinal microflora composition and volatile fatty acid production in a model organism, finding that kudzu vine extracts shifted the gut microbial community toward beneficial taxa and increased short-chain fatty acid output. The results suggest kudzu vine components could modulate gut health through microbiome-mediated mechanisms.
Emerging applications of postbiotics to sustainable livestock production systems
This review examines the emerging use of postbiotics, which are beneficial compounds produced by probiotic bacteria, as natural feed additives in livestock production. Researchers found that postbiotics show promise for improving animal growth, gut health, and fertility without the risks associated with live probiotic bacteria, such as antibiotic resistance gene transfer. The study suggests postbiotics could be a more stable and safer alternative for promoting sustainable animal production.
Resilience to Global Health Challenges Through Nutritional Gut Microbiome Modulation
This review explores how gut microbiome composition during early life influences long-term health, and how nutritional strategies can help build resilience against chronic diseases. Researchers highlight that environmental factors including microplastics and other contaminants can disrupt the developing gut microbiome, potentially contributing to allergies, obesity, and neurological conditions. The study suggests that targeted nutritional interventions to support healthy gut bacteria could help counteract some of these environmental exposures.
The concept of balance in microbiome research
This essay critically examines how the concept of "balance" is used in microbiome research and medical literature. Researchers analyzed multiple interpretations of what a balanced versus imbalanced microbiome means, finding that the term is often used loosely without precise scientific definition. The study argues for more rigorous conceptual frameworks to better understand how microbiome composition relates to health outcomes.