We can't find the internet
Attempting to reconnect
Something went wrong!
Hang in there while we get back on track
Postbiotic Sodium Butyrate Mitigates Hypertension and Kidney Dysfunction in Juvenile Rats Exposed to Microplastics
AI summary Read the abstract
This study reports that sodium butyrate, a postbiotic compound, mitigated microplastic-induced hypertension and kidney dysfunction in juvenile rats by reducing oxidative stress, modulating the gut microbiota, and elevating butyric acid levels.
Sodium butyrate holds potential for mitigating MP-induced hypertension by reducing oxidative stress, modulating the gut microbiota, and elevating butyric acid levels.
More Papers Like This
Resveratrol Butyrate Esters Reduce Hypertension in a Juvenile Rat Model of Chronic Kidney Disease Exacerbated by Microplastics
AI summary Read the abstract
Researchers found that resveratrol butyrate esters reduced high blood pressure in young rats that had both chronic kidney disease and microplastic exposure. The protective effects worked by improving nitric oxide levels, regulating the body's blood pressure control system, and positively shifting gut bacteria composition. The study suggests that certain natural compounds may help counteract the cardiovascular harm associated with microplastic exposure.
Protective Effect of Resveratrol on Kidney Disease and Hypertension Against Microplastics Exposure in Male Juvenile Rats
AI summary Read the abstract
Researchers investigated whether resveratrol, a natural plant compound, could protect young rats from kidney damage and high blood pressure caused by microplastic exposure. They found that microplastics elevated blood pressure and creatinine levels through oxidative stress, and that resveratrol treatment effectively prevented these effects. The study suggests resveratrol may offer protective benefits against organ damage linked to microplastic exposure, partly by improving gut microbiota balance.
Microplastic-induced hypertension in rats: A two-hit model exploring oxidative stress and gut microbiota
AI summary Read the abstract
Researchers used a two-hit model in rats to examine whether maternal microplastic exposure during pregnancy and nursing worsens the effects of direct microplastic exposure later in life. They found that combined maternal and postnatal exposure elevated blood pressure more than either exposure alone, with effects linked to oxidative stress and changes in gut bacteria. The study suggests that microplastic exposure may have compounding effects across generations, raising concerns about long-term cardiovascular and kidney health.
The influence of microplastics on hypertension-associated cardiovascular injury via the modulation of gut microbiota
AI summary Read the abstract
Researchers found that people with high blood pressure had more microplastics in their stool samples than healthy individuals, and feeding microplastics to mice raised their blood pressure and caused heart damage. The harm was linked to changes in gut bacteria, and a high-fiber diet or antibiotics helped reduce the damage. This study suggests microplastic exposure may worsen heart and blood pressure problems by disrupting the gut microbiome.
Exploring the Mechanismof Kidney Injury in Mice Inducedby High-Fat Diet and Polystyrene Nanoplastics Co-Exposure Throughthe Kidney-Gut Axis
AI summary Read the abstract
This mouse study found that combining a high-fat diet with polystyrene nanoplastic exposure (100 nm, 25 mg/kg/day) worsened kidney toxicity beyond high-fat diet alone, with the combination disrupting lipid metabolism via tryptophan and glycerophospholipid pathways and exacerbating gut microbiota dysbiosis through the kidney-gut axis.
Research digests by email
When a large batch of papers lands in the Atlas, we read through it and send a short write-up of what stood out.