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Causal relationship between gut microbiota and gastrointestinal diseases: a mendelian randomization study

Journal of Translational Medicine 2024 36 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count. Score: 75 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.

Kaiwen Wu, Qiang Luo, Yujing Liu, Aoshuang Li, Demeng Xia, Xiaobin Sun

Summary

This Mendelian randomization study found genetic evidence supporting a causal relationship between specific gut microbiota compositions and gastrointestinal diseases. The findings suggest that microbiome-related interventions, including microbiome-dependent metabolites, could potentially be developed to treat or manage gastrointestinal conditions.

Body Systems

Digestive

Models

Human

The findings of this study indicate a potential genetic predisposition linking gut microbiota to gastrointestinal diseases. These insights pave the way for designing future clinical trials focusing on microbiome-related interventions, including the use of microbiome-dependent metabolites, to potentially treat or manage gastrointestinal diseases and their associated risk factors.

Causal relationship between gut microbiota and gastrointestinal diseases: a mendelian randomization study

Summary

Discussion