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61,005 resultsShowing papers similar to Fermented Wheat Bran Polysaccharides Improved Intestinal Health of Zebrafish in Terms of Intestinal Motility and Barrier Function
ClearInhibitory Effects of Jiuzao Polysaccharides on Alcoholic Fatty Liver Formation in Zebrafish Larvae and Their Regulatory Impact on Intestinal Microbiota
Researchers investigated the protective effects of Laowuzeng Jiuzao polysaccharides on ethanol-induced alcoholic fatty liver in zebrafish larvae, finding that the polysaccharides reduced hepatic damage and regulated intestinal microbiota composition, suggesting therapeutic potential for alcohol-related liver disease.
Chestnut Shell Tannins: Effects on Intestinal Inflammation and Dysbiosis in Zebrafish
Researchers tested chestnut shell tannin extract in zebrafish with induced intestinal inflammation and dysbiosis, finding that tannin treatment reduced inflammatory markers and partially restored gut microbiome composition, suggesting potential as a natural anti-inflammatory dietary supplement.
The probiotic SLAB51 as agent to counteract BPA toxicity on zebrafish gut microbiota -liver-brain axis
Researchers tested whether the probiotic supplement SLAB51 could counteract the harmful effects of bisphenol A (BPA), a plastic-derived chemical, in zebrafish and found it significantly restored healthy gut bacteria, reduced liver damage, and protected the brain — suggesting probiotics may help offset harm from plastic-associated chemical exposure.
Zebrafish: an efficient vertebrate model for understanding role of gut microbiota
This review describes how zebrafish serve as an efficient vertebrate model for studying gut microbiota and host-microbe interactions. Researchers found that zebrafish share key similarities with humans in intestinal physiology, and their optical transparency and high fecundity make them uniquely suited for microbiome research. The study outlines methods for creating germ-free zebrafish and summarizes current understanding of gut microbiota functions in this model organism.
Dysregulation of gut health in zebrafish by differentially charged nanoplastic exposure: an integrated analysis of histopathology, immunology, and microbial informatics
Researchers studied how nanoplastics with different surface charges affect gut health in zebrafish using histopathology, immunology, and microbial analysis. The study found that gut damage and microflora disturbance caused by nanoplastic ingestion significantly depended on the surface functional groups of the particles.
Small fish, big discoveries: zebrafish shed light on microbial biomarkers for neuro-immune-cardiovascular health
This review highlighted how zebrafish serve as a powerful model for studying gut microbiome links to cardiovascular, neurological, and immune health, identifying microbial biomarkers that could inform future research on environmental stressor impacts including microplastic exposure.
Hermetia illucens in diets for zebrafish (Danio rerio): A study of bacterial diversity by using PCR-DGGE and metagenomic sequencing
Researchers studied how feeding zebrafish different diets based on black soldier fly larvae affected the bacterial diversity of the fish gut. Understanding gut microbiome responses to diet is relevant to assessing how microplastics ingested alongside food disrupt the gut microbiome of aquatic organisms.
The Gut-Brain-Microbiome Axis and Its Link to Autism: Emerging Insights and the Potential of Zebrafish Models
This review examines emerging evidence linking gut microbiome dysbiosis to autism spectrum disorder through the gut-brain axis, and discusses the potential of zebrafish as a model organism for investigating these connections and testing interventions.
Dietary Curcumin Promotes Gilthead Seabream Larvae Digestive Capacity and Modulates Oxidative Status
Adding curcumin to the diet of gilthead seabream larvae improved their digestive capacity and antioxidant status. The research explores natural dietary supplements for improving fish health in aquaculture, which is relevant as farmed seafood is a source of microplastic exposure for humans.
Role of dietary Schizochytrium sp. in improving disease resistance of zebrafish through metabolic and microbial analysis
Researchers found that substituting fish oil with marine microalgae Schizochytrium sp. in zebrafish diets improved disease resistance by altering gut microbiota and immune-related metabolic pathways. This is a fish nutrition and immunology study not directly related to environmental microplastics.
Effect of Probiotic Supplimentations on the Gut Histoarchitecture of Stinging Catfish, Heteropneustes fossilis
This aquaculture study evaluated the effects of probiotic supplementation on gut histology in stinging catfish, finding that probiotics improved intestinal morphology—relevant to understanding how gut health modifications may influence susceptibility to microplastic-induced gastrointestinal damage.
Microplastics induce intestinal inflammation, oxidative stress, and disorders of metabolome and microbiome in zebrafish
Researchers exposed zebrafish to polystyrene microplastics for 21 days and found significant intestinal inflammation, oxidative stress, and disruption of both the gut microbiome and metabolic processes. The microplastics altered the balance of beneficial and harmful gut bacteria and changed the levels of key metabolites involved in energy and amino acid metabolism. The study provides detailed evidence that microplastic ingestion can cause widespread disruption to gut health in aquatic organisms.
The Interaction between Oxidative Stress Biomarkers and Gut Microbiota in the Antioxidant Effects of Extracts from Sonchus brachyotus DC. in Oxazolone-Induced Intestinal Oxidative Stress in Adult Zebrafish
Researchers found that extracts from Sonchus brachyotus DC. alleviated oxazolone-induced intestinal oxidative stress in zebrafish by modulating antioxidant enzyme activity and reshaping gut microbiota composition.
Impacts of polystyrene nanoplastics on zebrafish gut microbiota and mechanistic insights
Zebrafish exposed to polystyrene nanoplastics showed significant changes in their gut bacteria, with beneficial species like Bifidobacterium declining and potentially harmful bacteria increasing. The nanoplastics physically entered intestinal tissues, causing visible damage to gut cells. This study is relevant to human health because our gut microbiome plays a key role in immunity and digestion, and similar disruption from nanoplastic exposure could contribute to digestive and immune problems.
Improvement of the intestinal epithelial barrier during laxative effects of phlorotannin in loperamide-induced constipation of SD rats
Researchers found that phlorotannin, a natural compound found in brown seaweed, relieves constipation in rats by repairing the intestinal epithelial barrier — the protective lining of the gut — suggesting it may support healthy gut function.
The zebrafish gut microbiome influences benzo[a]pyrene developmental neurotoxicity
Researchers found that the gut microbiome of zebrafish influences developmental neurotoxicity caused by benzo[a]pyrene, a polycyclic aromatic hydrocarbon, showing that microbial community composition modifies how the host responds to early-life toxicant exposure. The study highlighted gut-brain axis interactions as an important dimension of environmental toxicology.
Black Lycium barbarum polysaccharide attenuates LPS-induced intestine damage via regulation gut microbiota
Researchers studied whether a polysaccharide from black Lycium barbarum could protect against intestinal damage caused by bacterial toxins in mice. They found that the supplement alleviated intestinal tissue damage and improved gut microbiota diversity by promoting beneficial bacteria. The study suggests that this plant-derived polysaccharide may help maintain intestinal health by modulating the gut microbial community.
Effects of MP Polyethylene Microparticles on Microbiome and Inflammatory Response of Larval Zebrafish
Zebrafish larvae exposed to polyethylene microplastics for up to 10 days showed no broad metabolic disturbances or inflammatory changes, but oxidative stress markers increased at 15 days and the gut microbiome was disrupted, with higher levels of bacteria linked to intestinal disease. The findings suggest microplastics alter the microbial environment of fish guts without triggering obvious inflammation.
Impacts of dietary supplementation of bamboo vinegar and charcoal powder on growth performance, intestinal morphology, and gut microflora of large-scale loach Paramisgurnus dabryanus
Researchers fed large-scale loach fish diets supplemented with 1–2% bamboo vinegar and charcoal powder for 90 days and found significant improvements in survival, weight gain, intestinal villus length, and gut microbiome composition, suggesting this additive promotes digestive health and growth in aquaculture.
Effects of Long-Term Triclosan Exposure on Microbiota in Zebrafish
Long-term exposure to triclosan at environmentally relevant concentrations significantly altered gut microbiota composition in zebrafish, reducing microbial diversity and shifting community structure in ways that could affect host immune function and metabolism.
Interactions between intestinal microbiota and metabolites in zebrafish larvae exposed to polystyrene nanoplastics: Implications for intestinal health and glycolipid metabolism
Zebrafish larvae exposed to polystyrene nanoplastics suffered intestinal damage, including inflammation, oxidative stress, and disrupted gut bacteria -- with increases in bacteria linked to gut disease. The nanoplastics also altered metabolism related to sugar and fat processing, suggesting that ingesting these tiny particles could harm digestive health and disrupt how the body processes nutrients.
Positive effects of gamma aminobutyric acid on growth and lipopolysaccharide induced intestinal mucosal barrier damage in snakehead (Channa argus)
Supplementing snakehead fish (Channa argus) with gamma-aminobutyric acid improved growth performance and mitigated lipopolysaccharide-induced intestinal barrier damage, with GABA supplementation restoring tight junction protein expression and reducing intestinal permeability.
Modern research on the study of the intestinal microbiome in fish (review)
This review examines recent research on the intestinal microbiome of fish, synthesizing findings on microbiome composition across more than 100 teleost species and exploring the microbiome as a potential biomarker for fish health and aquaculture optimization.
Investigating the modulation of the endocannabinoid system by probiotic Lactiplantibacillus plantarum IMC513 in a zebrafish model of di-n-hexyl phthalate exposure
Researchers found that a probiotic strain (Lactiplantibacillus plantarum IMC513) protected zebrafish from neurological disruption caused by di-n-hexyl phthalate, a plasticizer chemical used in food packaging, by restoring normal gene expression in the brain's endocannabinoid signaling system. This suggests probiotics may help counteract the brain and gut effects of phthalate exposure from plastic products.