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Improvement of the intestinal epithelial barrier during laxative effects of phlorotannin in loperamide-induced constipation of SD rats
Summary
Researchers found that phlorotannin, a natural compound found in brown seaweed, relieves constipation in rats by repairing the intestinal epithelial barrier — the protective lining of the gut — suggesting it may support healthy gut function.
These results provide the first evidence that the laxative activity of Pt in SD rats with Lm-induced constipation phenotypes involve improvements in the IEB.
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