Papers

61,005 results
|
Article Tier 2

Two genes related to reproductive development in the juvenile prawn, Macrobrachium nipponense: Molecular characterization and transcriptional response to nanoplastic exposure

Nanoplastic exposure altered the expression of two genes involved in reproductive development in juvenile freshwater prawns (Macrobrachium nipponense), suggesting that nanoplastics may disrupt reproductive pathways in crustaceans at low concentrations.

2021 Chemosphere 17 citations
Article Tier 2

Polystyrene nanoplastics decrease molting and induce oxidative stress in adult Macrobrachium nipponense

Researchers found that polystyrene nanoplastics significantly decreased molting frequency and induced oxidative stress in adult freshwater prawns, with effects on antioxidant enzyme activities observed at environmentally relevant concentrations.

2022 Fish & Shellfish Immunology 37 citations
Article Tier 2

Change in energy-consuming strategy, nucleolar metabolism and physical defense in Macrobrachium rosenbergii after acute and chronic polystyrene nanoparticles exposure

Researchers examined how polystyrene nanoplastic exposure affects freshwater prawns over both short-term and long-term periods, finding significant changes in gene expression related to energy metabolism and physical defense. The study revealed that nanoplastic exposure disrupted nucleolar metabolism and triggered shifts in energy-consuming strategies, suggesting these particles pose a meaningful threat to aquatic crustaceans.

2023 Aquatic Toxicology 12 citations
Article Tier 2

Effects of nanoplastics on antioxidant and immune enzyme activities and related gene expression in juvenile Macrobrachium nipponense

Researchers explored the effects of nanoplastics on survival, antioxidant activity, immune enzyme activity, and gene expression in juvenile oriental river prawns. The study found that increasing nanoplastic concentrations suppressed antioxidant and immune enzyme activities while altering related gene expression levels, indicating that nanoplastic exposure can compromise the defense systems of freshwater crustaceans.

2020 Journal of Hazardous Materials 195 citations
Article Tier 2

Transcriptomic responses of Antarctic clam Laternula elliptica to nanoparticles, at single and combined exposures reveal ecologically relevant biomarkers

Researchers exposed Antarctic clams to polystyrene nanoparticles and titanium dioxide nanoparticles, finding that both types altered gene expression in ways affecting immune function, antioxidant defenses, lipid metabolism, and cell structure — with the combined exposure producing a distinct response. Four specific gene transcripts were identified as reliable biomarkers for nanoparticle exposure, offering tools for monitoring pollution in the fragile Antarctic ecosystem.

2024 Ecotoxicology and Environmental Safety 3 citations
Article Tier 2

Effects of nanoplastics on energy metabolism in the oriental river prawn (Macrobrachium nipponense)

Oriental river prawns exposed to polystyrene nanoplastics (5–40 mg/L) for up to 28 days showed concentration- and time-dependent decreases in survival and energy metabolism, including disrupted glycogen and triglyceride content, reduced metabolic enzyme activity, and altered gene expression of energy pathways.

2020 Environmental Pollution 110 citations
Article Tier 2

Abnormality of mussel in the early developmental stages induced by graphene and triphenyl phosphate: In silico toxicogenomic data-mining, in vivo, and toxicity pathway-oriented approach

Combining computational toxicogenomics with in vivo mussel embryo experiments, researchers found that graphene nanoparticles and the flame retardant triphenyl phosphate (TPP) — both associated with micro/nanoplastics in coastal waters — cause developmental abnormalities in mussel larvae through distinct but overlapping biological pathways. The study provides a mechanistic framework for understanding why plastic-associated chemicals are particularly damaging to marine invertebrates at early life stages.

2023 Aquatic Toxicology 2 citations
Article Tier 2

Decoding the molecular concerto: Toxicotranscriptomic evaluation of microplastic and nanoplastic impacts on aquatic organisms

This review summarizes existing research on how microplastics and nanoplastics affect gene activity in aquatic organisms including fish, crustaceans, and mollusks. The studies show that these tiny particles disrupt genes involved in immune defense, stress response, reproduction, and metabolism. Understanding these molecular-level changes is important because they reveal how microplastics could cause long-term health problems in animals that enter the human food chain.

2024 Journal of Hazardous Materials 15 citations
Article Tier 2

Effects of nanoplastic on cell apoptosis and ion regulation in the gills of Macrobrachium nipponense

Researchers exposed juvenile oriental river shrimp to varying concentrations of nanoplastics and examined effects on gill cell viability and ion regulation. They found that higher nanoplastic concentrations increased cell death rates, decreased ion content, reduced ATPase enzyme activity, and disrupted ion transport gene expression in gill tissues. The study suggests that nanoplastic pollution can impair critical ion regulation functions in freshwater crustaceans, with implications for aquaculture.

2022 Environmental Pollution 51 citations
Article Tier 2

Two genes related to apoptosis in the hepatopancreas of juvenile prawn, Macrobrachium nipponense: Molecular characterization and transcriptional response to nanoplastic exposure

Researchers identified and characterized two apoptosis-related genes in juvenile prawns exposed to polystyrene nanoplastics, finding that nanoplastic exposure induced significant apoptotic responses in hepatopancreas tissue in a concentration-dependent manner.

2023 The Science of The Total Environment 11 citations
Article Tier 2

Effects of Microplastics, Polystyrene, and Polyethylene on Antioxidants, Metabolic Enzymes, HSP-70, and Myostatin Expressions in the Giant River Prawn Macrobrachium rosenbergii: Impact on Survival and Growth

Researchers exposed juvenile giant river prawns (Macrobrachium rosenbergii) to polystyrene microspheres and polyethylene microparticles and found that both types reduced survival and growth while increasing oxidative stress markers and altering expression of heat shock proteins and myostatin, with polystyrene causing more severe effects.

2021 Archives of Environmental Contamination and Toxicology 34 citations
Article Tier 2

Effects of nanoplastic exposure on the growth performance and molecular characterization of growth-associated genes in juvenile Macrobrachium nipponense

Researchers found that polystyrene nanoplastic exposure impaired growth in juvenile shrimp by damaging the hepatopancreas, disrupting digestive enzyme activity, and altering growth-related gene expression at concentrations above 10 mg/L.

2022 Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology 22 citations
Article Tier 2

Polystyrene nanoplastics decrease nutrient accumulation, disturb sex hormones, and inhibit reproductive development in juvenile Macrobrachium nipponense

Researchers exposed juvenile oriental river prawns to polystyrene nanoplastics at various concentrations for 28 days and observed significant disruptions to their reproductive development. The nanoplastics reduced nutrient accumulation, altered sex hormone levels, and interfered with genes involved in gonad development. The study suggests that nanoplastic pollution in waterways could impair the reproductive health of crustacean species.

2023 The Science of The Total Environment 22 citations
Article Tier 2

Toxicity of environmental and polystyrene plastic particles on the bivalve Corbicula fluminea: focus on the molecular responses

Researchers exposed freshwater bivalves to environmental microplastics and nanoplastics collected from a river, as well as to laboratory polystyrene nanoparticles, and measured molecular-level responses. Gene expression analysis revealed that plastic particle exposure activated stress response and immune defense pathways in gill and visceral tissues. The study indicates that even environmentally relevant concentrations of plastic particles can trigger measurable biological stress in filter-feeding organisms.

2024 Ecotoxicology 2 citations
Article Tier 2

Response of moulting genes and gut microbiome to nano-plastics and copper in juvenile horseshoe crab Tachypleus tridentatus

Researchers exposed juvenile horseshoe crabs to polystyrene nanoplastics and copper, both alone and in combination, and found that combined exposure significantly altered molting gene expression and disrupted gut microbial communities. The nanoplastics and copper together triggered stress responses not seen with either pollutant alone, including changes in heat shock protein and hormone receptor gene activity. The study raises concerns about how multiple pollutants in coastal waters may jointly affect the development of this ancient and ecologically important species.

2023 Marine Environmental Research 21 citations
Article Tier 2

Recent Findings in Adverse Effects of Tio2 NPs in Marine Algae and Zooplanktons: A Threat to Marine Ecosystems

This review summarizes recent findings on the harmful effects of titanium dioxide nanoparticles on marine algae and zooplankton. Researchers found that these nanoparticles can cause oxidative stress, DNA damage, and disruptions to cellular processes in marine organisms. The study highlights that TiO2 nanoparticles often interact with other pollutants like microplastics in marine environments, potentially amplifying their combined ecological impact.

2024 The International Journal of Maritime Engineering 2 citations
Article Tier 2

Do Waterborne Nanoplastics Affect the Shore Crab Carcinus maenas? A Case Study with Poly(methyl)methacrylate Particles

Researchers exposed shore crabs (Carcinus maenas) to waterborne nanoplastics and assessed multiple physiological endpoints, finding that nanoplastic exposure altered immune function, oxidative stress markers, and gene expression in ways that indicate significant sublethal harm to this ecologically important species.

2025 Environments
Article Tier 2

Polyethylene terephthalate microfibers change molting patterns of Penaeus vannamei in a benthic exposure system

Researchers exposed whiteleg shrimp to polyethylene terephthalate microfibers for 21 days and found that the fibers negatively affected growth, altered molting cycles, and caused structural damage to the hepatopancreas and intestines. Molecular analysis revealed that the microfibers disrupted molting hormones and chitin biosynthesis pathways. The study highlights that fibrous microplastics on the seafloor may pose significant risks to commercially important crustacean species.

2025 Marine Pollution Bulletin 1 citations
Article Tier 2

Transcriptomic analysis following polystyrene nanoplastic stress in the Pacific white shrimp, Litopenaeus vannamei

Researchers used transcriptomic analysis to study how polystyrene nanoplastics affect gene expression in Pacific white shrimp. They found that nanoplastic exposure activated lysosome pathways and disrupted genes involved in immune response, protein processing, and metabolism. The study provides molecular-level evidence that nanoplastics can interfere with multiple biological systems in commercially important shrimp species.

2023 Fish & Shellfish Immunology 15 citations
Article Tier 2

Toxicological effects of graphene on mussel Mytilus galloprovincialis hemocytes after individual and combined exposure with triphenyl phosphate

Researchers exposed mussel immune cells to graphene nanoparticles and the flame retardant triphenyl phosphate, finding that each contaminant alone induced oxidative stress and DNA damage, but their combination paradoxically reduced these harmful effects by activating cell-survival gene pathways.

2020 Marine Pollution Bulletin 25 citations
Article Tier 2

Polystyrene nanoplastic induces oxidative stress, immune defense, and glycometabolism change in Daphnia pulex: Application of transcriptome profiling in risk assessment of nanoplastics

Researchers used transcriptome sequencing to examine how polystyrene nanoplastics affect gene expression in the water flea Daphnia pulex. After 96 hours of exposure, they identified 208 genes with altered expression levels, linked to oxidative stress, immune defense, and sugar metabolism pathways. The study provides molecular-level evidence that nanoplastic pollution can trigger multiple stress responses in freshwater organisms.

2020 Journal of Hazardous Materials 167 citations
Article Tier 2

Regulation of target genes transcription in copepods Acartia tonsa waterborne or foodborne exposed to naked or metal-doped nanoplastics of different sizes and polymer composition

Researchers exposed the marine copepod Acartia tonsa to nanoplastics via waterborne and foodborne routes and measured transcriptional responses in target genes. Exposure route influenced gene expression patterns, with foodborne exposure producing distinct molecular responses compared to direct waterborne contact.

2024 Zenodo (CERN European Organization for Nuclear Research)
Article Tier 2

Evaluation of microplastic toxicity in accordance with different sizes and exposure times in the marine copepod Tigriopus japonicus

Researchers exposed marine copepods to polystyrene microbeads of two different sizes to understand how particle size and exposure duration affect toxicity. They found that both nano-sized and micro-sized particles increased reactive oxygen species levels inside cells and altered antioxidant gene expression and enzyme activity. The study provides important molecular-level evidence that microplastic toxicity in marine organisms depends on both the size of the particles and how long organisms are exposed.

2019 Marine Environmental Research 210 citations
Article Tier 2

Toxicity evaluation of nano-TiO2 in the presence of functionalized microplastics at two trophic levels: Algae and crustaceans

Researchers examined how different surface-functionalized polystyrene microplastics affect the toxicity of titanium dioxide nanoparticles across two trophic levels, using algae and brine shrimp. They found that aminated and plain microplastics enhanced nano-TiO2 toxicity to algae, while carboxylated microplastics reduced it. Direct aqueous exposure caused greater toxicity in brine shrimp than dietary exposure, suggesting that the route of exposure significantly influences combined contaminant effects.

2021 The Science of The Total Environment 55 citations