Papers

61,005 results
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Article Tier 2

Allergy and immunotoxicology in preventive and clinical medicine from theory to practice: Environmental factors in bronchial asthma

This review applies an exposome framework to bronchial asthma, identifying living-environment pollutants including microplastics, air pollution, tobacco smoke, climate change, and dietary changes as contributors to asthma pathogenesis and exacerbation.

2024 SANGYO EISEIGAKU ZASSHI 1 citations
Article Tier 2

The interconnection between environment, immune-nutrition and allergic disease

This review explores the connections between environmental factors, immune-nutrition, and the rising global prevalence of allergic diseases. The study discusses how climate change, air pollution, biodiversity loss, and environmental contaminants including microplastics contribute to immune dysregulation, and highlights the role of the microbiome and dietary factors in modulating allergic disease risk.

2026 Asia Pacific Allergy
Meta Analysis Tier 1

Climate change and the epithelial barrier theory in allergic diseases: A One Health approach to a green environment

This review links climate change and increased environmental pollution to the weakening of epithelial barriers in the skin, gut, and lungs, contributing to the rise of allergic diseases worldwide. The paper specifically identifies microplastics alongside other pollutants as agents that damage epithelial barriers, suggesting a mechanism by which microplastic exposure could contribute to allergies and autoimmune conditions.

2023 Allergy 19 citations
Article Tier 2

Confronting allergies: strategies for combating pollution and safeguarding our health

This review examined the growing body of evidence linking environmental pollutants, including airborne microplastics, to increasing rates of allergic reactions worldwide. Researchers found that air pollution and indoor contaminants can worsen respiratory allergies, while climate change intensifies seasonal allergy patterns. The study emphasizes the need for comprehensive action including government regulation and public awareness to reduce pollution-driven allergy risks.

2025 Frontiers in Allergy 2 citations
Article Tier 2

The Concept of One Health for Allergic Diseases and Asthma

This review examined how climate change, biodiversity loss, and environmental pollutants including microplastics contribute to rising allergic disease prevalence worldwide, advocating for a One Health approach that integrates human, animal, and ecosystem health strategies.

2023 Allergy Asthma and Immunology Research 12 citations
Article Tier 2

To breathe or not to breathe: Implications of hazardous air quality

This review examines the relationship between climate change, worsening air quality, and associated human health impacts, focusing on the spectrum of respiratory diseases and cancers linked to air pollution. The authors argue that governments and public health sectors must strengthen pollution control policies and reduce carbon and other pollutants to protect population health.

2022
Article Tier 2

The External Exposome and Allergies: From the Perspective of the Epithelial Barrier Hypothesis

This review examines how environmental changes including air pollution, global warming, and shifting dietary habits damage epithelial barriers in the body, contributing to increased rates of allergies and inflammation. The authors highlight the need for public awareness and government policies to address the health effects of environmental exposures on current and future generations.

2022 Frontiers in Allergy 60 citations
Article Tier 2

Respiratory Health Impacts from Natural Disasters and Other Extreme Weather Events: The Role of Environmental Stressors on Asthma and Allergies

This review looked at how natural disasters and extreme weather events, including wildfires, floods, and heat waves, are worsening respiratory conditions like asthma and allergies. Researchers found that these events release environmental stressors including microplastics and PFAS chemicals that can trigger lung inflammation and immune disruption. The study suggests that as extreme weather becomes more frequent, understanding these exposure pathways is increasingly important for protecting respiratory health.

2025 Current Allergy and Asthma Reports 4 citations
Article Tier 2

Influence of climate change on emerging pathogens and human immunity

This review discusses how climate change-driven shifts in temperature, precipitation, and extreme weather events are altering the distribution and virulence of emerging pathogens, with downstream consequences for human and animal immunity. The authors examine interactions between environmental change, pathogen adaptation, and immune function, arguing that climate mitigation is essential for maintaining disease resistance in human populations.

2024 Egyptian journal of Immunology 1 citations
Article Tier 2

Environmental Science in Allergy and Asthma

This review summarizes presentations from the 2022 EAACI Hybrid Congress on environmental science in allergy and asthma, covering the links between climate change, air quality degradation, and the incidence and severity of allergic diseases. Researchers highlighted new EAACI guidelines on environmental impacts from inception to disease severity, noting that climate-driven changes in pollen seasons, air pollutants, and indoor allergen exposure are increasingly relevant to clinical allergy management.

2022 EMJ Allergy & Immunology
Article Tier 2

Immune-mediated disease caused by climate change-associated environmental hazards: mitigation and adaptation

This review examines how climate change-driven events like wildfires, dust storms, and heatwaves increase air pollution and allergen exposure, contributing to rising rates of asthma, autoimmune diseases, and cancer. The paper specifically notes that nanoplastics, alongside other environmental pollutants, can disrupt skin and mucous membrane barriers and alter the microbiome in ways that trigger immune system dysfunction.

2024 Frontiers in Science 45 citations
Article Tier 2

Public perceptions of climate change and health – A cross-sectional survey study

Researchers conducted a cross-sectional survey to assess public perceptions of the links between climate change and human health, examining awareness of how rising temperatures, extreme weather, air pollution, and environmental degradation affect morbidity and mortality. The study found variable levels of public understanding across demographic groups, with implications for health communication and climate policy engagement.

2022 Research Square (Research Square)
Article Tier 2

Cellular and molecular mechanisms of allergic asthma

Researchers reviewed the cellular and molecular mechanisms behind allergic asthma, finding that rising exposure to environmental pollutants — including microplastics — likely contributes to the disease's increasing prevalence, as pollutants disrupt airway barrier integrity and trigger immune responses that lead to chronic airway inflammation.

2021 Molecular Aspects of Medicine 243 citations
Article Tier 2

ERS International Congress 2022: highlights from the Basic and Translational Science Assembly

This review highlights key findings from the 2022 European Respiratory Society Congress on how climate change, air pollution, microplastics, and early-life events affect respiratory health, alongside advances in the Human Lung Cell Atlas, cell death pathways in lung disease, and novel asthma therapies.

2023 ERJ Open Research 7 citations
Article Tier 2

Asthma and allergic diseases: Cross talk of immune system and environmental factors

This review summarizes current understanding of how environmental factors, including the microbiome and geographic location, influence immune regulation in the context of allergy and asthma. Researchers examined how different routes of exposure to environmental agents interact with both innate and adaptive immune responses. The study highlights the need for comprehensive investigation of environmentally driven immune changes to better understand disease prevention and progression.

2023 European Journal of Immunology 19 citations
Article Tier 2

Health Psychology and Climate Change: Time to address humanity’s most existential crisis

This paper argues that health psychology must urgently address climate change as humanity's most existential health crisis, highlighting how greenhouse gas emissions drive extreme weather, displacement, food insecurity, and disease disproportionately affecting vulnerable populations.

2023 7 citations
Article Tier 2

One Health in allergology: A concept that connects humans, animals, plants, and the environment

This review applies the One Health framework to allergology, arguing that the increasing prevalence of allergic diseases reflects interconnections between human, animal, and environmental health, with environmental contaminants including microplastics among the discussed contributing factors.

2021 Allergy 17 citations
Article Tier 2

Risk factors for the prevalence and development of allergic diseases

This review synthesized evidence on risk factors for the development of allergic diseases, covering genetic predisposition, early-life microbial exposure, diet, air pollution, and emerging exposures including microplastics. The authors discuss how environmental changes have driven rising allergy prevalence and identify microplastics as a candidate contributing factor warranting further study.

2024 Liječnički vjesnik
Article Tier 2

The climate crisis in clinical practice: Addressing air pollution, heat, and microplastics

This review examines how climate change-driven environmental threats including air pollution, extreme heat, and microplastics are already affecting patients in clinical settings. Researchers found that these exposures disproportionately harm vulnerable populations and that physicians need to be equipped to recognize and address the health effects of environmental degradation. The study argues that healthcare professionals have a critical role to play in both treating affected patients and advocating for policies that reduce fossil fuel-related pollution.

2025 European Journal of Internal Medicine 2 citations
Article Tier 2

Airway exposure to microplastics: Potential mechanisms from epithelial barrier damage to the development of allergic rhinitis

This review summarized the mechanisms by which airborne microplastic exposure triggers allergic rhinitis, identifying pathways including physical and chemical disruption of the airway epithelial barrier, oxidative stress from adsorbed pollutants, and induction of Th2 immune responses and IgE class-switching. The findings support airborne MPs as a novel trigger for upper respiratory allergic disease.

2025 Environmental Research
Article Tier 2

Residential environment in relation to self-report of respiratory and asthma symptoms among primary school children in a high-polluted urban area

Researchers surveyed 658 Bangkok schoolchildren and found that living near garment shops, having pests at home, and having damp walls were each independently linked to higher rates of asthma and respiratory symptoms, underscoring how indoor and neighborhood environments directly affect children's lung health.

2022 Scientific Reports 9 citations
Article Tier 2

Climate Change, Environment, and One Health

This review discusses how climate change drives biodiversity loss, air and water pollution, and the spread of microplastics, collectively increasing the burden of non-communicable diseases and putting pressure on healthcare systems, especially in lower-income countries.

2025
Article Tier 2

Infectious disease ecology and evolution in a changing world

This study examines how changing environmental conditions, particularly thermal shifts, can influence infectious disease dynamics. The research suggests that temperature conditions can strongly affect both host and pathogen traits related to infection.

2023 Philosophical Transactions of the Royal Society B Biological Sciences 20 citations
Article Tier 2

Winds of change a tale of: asthma and microbiome

This review explores the relationship between the human microbiome and asthma, considering how environmental factors including air pollution and microplastics may influence microbial communities in the airways. Researchers found that changes in the lung and gut microbiome are associated with altered immune responses that can worsen asthma symptoms. The study suggests that environmental exposures, including airborne microplastics, may contribute to asthma development by disrupting the body's natural microbial balance.

2023 Frontiers in Microbiology 17 citations