Papers

61,005 results
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Article Tier 2

Effect of dietary Bacillus subtilis supplement on Cd toxicokinetics and Cd-induced immune and antioxidant impairment of Procambarus clarkii

Researchers exposed red swamp crayfish to cadmium at 0.1 and 1.0 mg/L with and without dietary Bacillus subtilis supplementation, finding dose- and time-dependent cadmium accumulation with gills showing highest uptake, and demonstrating that Bacillus subtilis supplementation ameliorated cadmium-induced immune and antioxidant impairment across crayfish tissues.

2022 Research Square (Research Square)
Article Tier 2

Dietary Pectin Supplementation as a Potential Strategy to Mitigate the Toxic Effects of Microplastics and Cadmium in Freshwater Crayfish ( Astacus leptodactylus )

Researchers investigated whether dietary pectin supplementation could mitigate the toxic effects of microplastics and cadmium exposure in freshwater crayfish. Pectin partially restored some antioxidant enzyme activities and normalized certain biochemical markers disrupted by the pollutant exposure. However, because the crayfish were directly exposed to the contaminants in water, oral pectin supplementation had limited protective effects on several key health parameters, suggesting that dietary interventions alone may not fully counteract environmental pollutant exposure.

2026 Aquaculture Research
Article Tier 2

Effects of Hypoxia Stress on Survival, Antioxidant and Anaerobic Metabolic Enzymes, and Related Gene Expression of Red Swamp Crayfish Procambarus clarkii

Researchers studied how hypoxia stress affects the survival, antioxidant defenses, and metabolic enzyme activity of red swamp crayfish at different temperatures. The study found that oxygen consumption rates and stress responses varied significantly with both temperature and dissolved oxygen levels, providing important data for managing crayfish aquaculture conditions to reduce mortality from low-oxygen events.

2024 Biology 10 citations
Article Tier 2

Accumulation of polyethylene microplastics induces oxidative stress, microbiome dysbiosis and immunoregulation in crayfish

Researchers exposed crayfish (Procambarus clarkii) to polyethylene microplastics through their diet for 21 days and found that particles accumulated in the intestine, hepatopancreas, gills, and blood, persisting even after a week of depuration in clean water. The accumulated microplastics caused oxidative stress, disrupted the gut microbiome, and altered immune regulation. The study suggests that microplastic exposure may compromise the health and immune defenses of commercially important freshwater crustaceans.

2022 Fish & Shellfish Immunology 60 citations
Article Tier 2

Microplastics in feed cause sublethal changes in the intestinal microbiota and a non-specific immune response indicator of the freshwater crayfish Procambarus clarkii (Decapoda: Cambaridae)

Researchers fed freshwater crayfish a diet containing recycled PET microplastics and examined the effects on gut bacteria and immune function. They found that microplastic exposure caused an imbalance in intestinal microbiota, increasing potentially harmful bacteria while decreasing beneficial species. The study also showed a weakened immune response, suggesting that microplastic contamination in aquatic food sources can compromise the health of the organisms that consume them.

2023 Frontiers in Microbiology 15 citations
Article Tier 2

The effect of a polystyrene nanoplastic on the intestinal microbes and oxidative stress defense of the freshwater crayfish, Procambarus clarkii

Researchers tested the acute effects of polystyrene nanoplastics on freshwater crayfish and found that exposure altered the composition of intestinal bacteria and disrupted oxidative stress defenses. Higher concentrations of nanoplastics led to more severe changes in gut microbial diversity and antioxidant enzyme activity. The study adds to growing evidence that nanoplastic pollution can harm the gut health and immune defenses of freshwater organisms.

2022 The Science of The Total Environment 84 citations
Article Tier 2

Effects of nanoplastic exposure on the immunity and metabolism of red crayfish (Cherax quadricarinatus) based on high-throughput sequencing

Researchers examined nanoplastic effects on red crayfish using transcriptomics and microbiome analysis, finding that high concentrations suppressed antioxidant and immune responses while significantly altering gut microbial communities.

2022 Ecotoxicology and Environmental Safety 25 citations
Article Tier 2

Selenium-containing polysaccharide from Spirulina platensis alleviates Cd-induced toxicity in mice by inhibiting liver inflammation mediated by gut microbiota

Researchers found that selenium-containing polysaccharide from Spirulina platensis alleviates cadmium-induced liver toxicity in mice by modulating gut microbiota composition and suppressing inflammatory pathways, suggesting a protective role against heavy metal exposure.

2022 Frontiers in Nutrition 25 citations
Article Tier 2

Probiotics, Prebiotics, and Synbiotics Utilization in Crayfish Aquaculture and Factors Affecting Gut Microbiota

This review examines how probiotics, prebiotics, and synbiotics can improve gut health and disease resistance in farmed crayfish. These supplements help maintain beneficial gut bacteria, boost immune function, and reduce the need for antibiotics in aquaculture. The research is relevant to microplastic concerns because healthy gut microbiomes in aquatic organisms may be more resilient to disruption from environmental contaminants like microplastics.

2023 Microorganisms 40 citations
Article Tier 2

Oxidative stress and histopathological effects by microplastic beads, in the crayfish Procambarus clarkii, and fiddler crab Leptuca pugilator

Researchers exposed crayfish and fiddler crabs to polystyrene microplastic beads for one month and examined the effects on their hepatopancreas, a key digestive organ. Both species showed signs of oxidative stress and tissue damage, with microplastic particles accumulating in their organs. The study provides evidence that even at moderate concentrations, microplastic exposure can cause measurable physiological harm to freshwater and coastal crustaceans.

2023 Chemosphere 19 citations
Article Tier 2

Comparison of Intestinal Bacteria of Procambarus clarkii Farmed in Various Rice Paddy Regions

Researchers analyzed gut microbiota in red swamp crayfish (Procambarus clarkii) farmed across different rice paddy regions of China, finding significant regional differences in intestinal bacterial communities linked to local environmental conditions.

2024 Animals 5 citations
Article Tier 2

Intensified carotenoid accumulation in Rhodotorula mucilaginosa under Pb Stress

Scientists studied how a type of yeast responds to toxic metals like lead and cadmium by producing carotenoids—the same healthy compounds that give carrots their orange color. They found that the yeast makes more carotenoids when exposed to lead compared to cadmium, which helps protect the cells from damage. This research could help us better understand how to use beneficial microorganisms to clean up metal pollution in the environment, potentially reducing human exposure to these harmful substances.

2026
Article Tier 2

Protective Efficacy of Dietary Yeast (Saccharomyces cerevisiae) Against Microplastic Toxicity in the Nile Tilapia (Oreochromis niloticus): Studies on Growth Performance, Gene Expression, Biochemistry, and Immune Response

Researchers tested whether dietary supplementation with the yeast Saccharomyces cerevisiae could protect Nile tilapia from microplastic-induced toxicity, assessing growth, feed utilization, gene expression, biochemical markers, and immune responses in 270 juvenile fish. Yeast supplementation showed protective effects against microplastic-related stress in the fish.

2024 Egyptian Journal of Aquatic Biology and Fisheries 1 citations
Article Tier 2

Toxicity effects of microplastics individually and in combination with Aeromonas hydrophila on freshwater crayfish (Astacus leptodactylous)

Researchers investigated the combined effects of microplastics and the pathogenic bacterium Aeromonas hydrophila on freshwater crayfish over 30 days. The study found that co-exposure to microplastics and the pathogen caused more severe disruptions to blood biochemistry, liver oxidative balance, and immune function than either stressor alone, suggesting microplastics can amplify pathogen-related damage.

2024 Environmental Science and Pollution Research 2 citations
Article Tier 2

Chronic Microplastic Exposure and Cadmium Accumulation in Blue Crabs

Researchers exposed blue crabs (Callinectes sapidus) to virgin and oxidised microplastics for 118 days and found no significant effect on cadmium accumulation in haemolymph or tissues including hepatopancreas, gills, and muscles. However, oxidised microplastics showed a positive correlation between cadmium concentrations in hepatopancreas and muscle tissue, raising potential food safety concerns.

2022 International Journal of Environmental Research and Public Health 7 citations
Article Tier 2

Histopathological and intestinal microbial changes in crayfish (Procambarus clarkii) after exposure to polyethylene nanoparticles (PE-NPS) and their remediation by Spirulina platensis

Researchers found that polyethylene nanoparticles caused significant intestinal tissue damage and disrupted gut microbial communities in crayfish, and that supplementing their diet with the microalgae Spirulina platensis partially reversed these effects by restoring intestinal cell arrangement and reducing vacuolization in digestive tissues.

2025 Marine Pollution Bulletin 1 citations
Article Tier 2

Integrated analysis of zebrafish gut microbiota and liver transcriptome responses to polystyrene microplastics and cadmium

Researchers exposed zebrafish to polystyrene microplastics and cadmium, both individually and combined, and found that combined exposure caused more severe disruption to gut bacteria and liver gene expression than either pollutant alone. The study revealed that microplastics decreased beneficial gut bacteria while increasing pathogenic species, and the combined treatment suppressed liver xenobiotic metabolism and antioxidant pathways.

2026 Aquaculture Reports
Article Tier 2

Effects of Polystyrene Microplastics on Hepatopancreas Histology, Intestinal Microbiota, and Metabolic Response in Cherax quadricarinatus

Researchers exposed redclaw crayfish to different concentrations of polystyrene microplastics and examined the effects on organ tissue, gut microbiota, and metabolism. At high concentrations, microplastics caused damage to hepatopancreatic tissues, shifted gut bacterial communities toward potentially harmful species, and disrupted amino acid metabolic pathways. The study suggests that microplastic pollution in freshwater environments can have cascading effects on the internal biology of aquatic crustaceans.

2026 Aquaculture Research
Article Tier 2

Effects of Different Sources of Culture Substrate on the Growth and Immune Performance of the Red Swamp Crayfish (Procambarus clarkii)

Researchers evaluated the effects of culture substrates from different sources on the growth performance and immune enzyme activity of red swamp crayfish (Procambarus clarkii), measuring weight gain rate, body length growth rate, specific growth rate, and activities of acid phosphatase, alkaline phosphatase, and superoxide dismutase. The substrate designated as group I2 produced the highest growth and immune performance scores, significantly outperforming other substrate groups.

2023 International Journal of Molecular Sciences 4 citations
Article Tier 2

Different geographical environment can affect the fatty acid compositions of the Red Swamp Crayfish (Procambarus clarkii) through the intestinal flora

Not relevant to microplastics — this study examines how geographic environment and gut microbiota influence the fatty acid composition and nutritional quality of red swamp crayfish (Procambarus clarkii).

2023 Research Square (Research Square)
Article Tier 2

Exploring the Coexposure Effects of Pyrogallol and Microplastic on the Red Swamp Crayfish Procambarus clarkii

Researchers exposed freshwater crayfish to microplastics and pyrogallol (a plant-derived chemical) both alone and together, and found that the combination caused worse damage than either pollutant alone. The crayfish showed liver damage, reduced antioxidant defenses, and immune system changes. Since crayfish are a common food source, this study highlights how microplastics interacting with other environmental chemicals could affect food safety.

2025 Aquaculture Research 7 citations
Article Tier 2

Toxicology Effects of Cadmium in Pomacea canaliculate: Accumulation, Oxidative Stress, Microbial Community, and Transcriptome Analysis

Researchers studied how cadmium, a toxic heavy metal, accumulates in apple snails, finding the liver absorbed the highest concentrations and that antioxidant defenses remained damaged even after the cadmium exposure ended. While focused on cadmium rather than microplastics, the study is relevant because microplastics are known to absorb and transport cadmium in aquatic environments. This means microplastics could increase cadmium delivery to freshwater organisms and, through the food chain, to humans.

2025 International Journal of Molecular Sciences 6 citations
Article Tier 2

Seaweed polysaccharide relieves hexavalent chromium-induced gut microbial homeostasis

Researchers found that seaweed polysaccharides can restore gut microbial balance disrupted by hexavalent chromium exposure in mice, reducing pathogenic bacteria and increasing beneficial species, suggesting a potential dietary intervention for heavy metal-induced intestinal damage.

2023 Frontiers in Microbiology 12 citations
Article Tier 2

Toxic mechanisms of nanoplastics exposure at environmental concentrations on juvenile red swamp crayfish (Procambarus clarkii): From multiple perspectives

Researchers exposed juvenile red swamp crayfish to nanoplastics at concentrations found in the environment and observed stunted growth, oxidative stress, liver and gill damage, and changes in gene activity. Different concentrations triggered different toxic pathways, including immune disruption and metabolic problems. Since crayfish are a widely consumed freshwater species, these findings raise concerns about nanoplastic contamination in the food supply.

2024 Environmental Pollution 15 citations