Papers

61,005 results
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Article Tier 2

Antioxidant Capacity, Enzyme Activities Related to Energy Metabolism, and Transcriptome Analysis of Crassostrea hongkongensis Exposed to Hypoxia

Researchers studied how low-oxygen conditions affect the antioxidant defenses and energy metabolism of the Hong Kong oyster, an important aquaculture species in China. They found that hypoxia significantly altered enzyme activity related to energy production and caused oxidative stress in the oysters. The study provides insights into how seasonal oxygen depletion in coastal waters threatens oyster health and aquaculture productivity.

2024 Antioxidants 5 citations
Article Tier 2

Saccharomyces cerevisiae additions normalized hemocyte differential genes expression and regulated crayfish (Procambarus clarkii) oxidative damage under cadmium stress

Researchers tested whether adding the probiotic yeast Saccharomyces cerevisiae to crayfish feed could reduce cadmium (a toxic heavy metal) accumulation in the animals, finding that a 5% supplementation removed over 66% of cadmium after 21 days while also reducing oxidative damage. The findings suggest this probiotic approach could help produce safer, cadmium-free farmed crayfish.

2023 Scientific Reports 5 citations
Article Tier 2

Effect of dietary Bacillus subtilis supplement on Cd toxicokinetics and Cd-induced immune and antioxidant impairment of Procambarus clarkii

Researchers exposed red swamp crayfish to cadmium at 0.1 and 1.0 mg/L with and without dietary Bacillus subtilis supplementation, finding dose- and time-dependent cadmium accumulation with gills showing highest uptake, and demonstrating that Bacillus subtilis supplementation ameliorated cadmium-induced immune and antioxidant impairment across crayfish tissues.

2022 Research Square (Research Square)
Article Tier 2

Physiological response of freshwater crayfish, Astacus leptodactylus exposed to polyethylene microplastics at different temperature

Freshwater crayfish exposed to polyethylene microplastics showed liver stress, disrupted blood chemistry, and weakened immune responses, with higher temperatures making the effects worse. The combination of microplastic exposure and warmer water caused greater damage to antioxidant defenses and enzyme activity than either stressor alone. As climate change raises water temperatures, aquatic organisms may become more vulnerable to microplastic toxicity, which could affect the safety of freshwater species consumed by humans.

2023 Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology 78 citations
Article Tier 2

Effects of Different Sources of Culture Substrate on the Growth and Immune Performance of the Red Swamp Crayfish (Procambarus clarkii)

Researchers evaluated the effects of culture substrates from different sources on the growth performance and immune enzyme activity of red swamp crayfish (Procambarus clarkii), measuring weight gain rate, body length growth rate, specific growth rate, and activities of acid phosphatase, alkaline phosphatase, and superoxide dismutase. The substrate designated as group I2 produced the highest growth and immune performance scores, significantly outperforming other substrate groups.

2023 International Journal of Molecular Sciences 4 citations
Article Tier 2

Long-term hypoxia and reoxygenation induced oxidative stress lead to immunosuppression and apoptosis in golden pompano (Trachinotus blochii)

Researchers exposed golden pompano fish to 14 days of low-oxygen conditions followed by reoxygenation and found that this hypoxia-reoxygenation cycle caused oxidative stress, immunosuppression, and increased liver cell apoptosis.

2023 Frontiers in Marine Science 22 citations
Article Tier 2

Toxic mechanisms of nanoplastics exposure at environmental concentrations on juvenile red swamp crayfish (Procambarus clarkii): From multiple perspectives

Researchers exposed juvenile red swamp crayfish to nanoplastics at concentrations found in the environment and observed stunted growth, oxidative stress, liver and gill damage, and changes in gene activity. Different concentrations triggered different toxic pathways, including immune disruption and metabolic problems. Since crayfish are a widely consumed freshwater species, these findings raise concerns about nanoplastic contamination in the food supply.

2024 Environmental Pollution 15 citations
Article Tier 2

Exploring the Coexposure Effects of Pyrogallol and Microplastic on the Red Swamp Crayfish Procambarus clarkii

Researchers exposed freshwater crayfish to microplastics and pyrogallol (a plant-derived chemical) both alone and together, and found that the combination caused worse damage than either pollutant alone. The crayfish showed liver damage, reduced antioxidant defenses, and immune system changes. Since crayfish are a common food source, this study highlights how microplastics interacting with other environmental chemicals could affect food safety.

2025 Aquaculture Research 7 citations
Article Tier 2

Hypoxia in the Blue Mussel Mytilus chilensis Induces Transcriptome Shift Associated with Endoplasmic Reticulum Stress, Metabolism, and Immune Response.

Scientists used gene expression analysis to study how low-oxygen conditions affect the blue mussel Mytilus chilensis at the molecular level. Researchers found that hypoxia triggered stress responses in the mussels' gills, digestive glands, and muscles, including cellular stress pathways, metabolic shifts, and immune changes. The study highlights how climate-driven oxygen depletion in coastal waters can stress economically important shellfish species.

2024 Preprints.org 5 citations
Article Tier 2

Combined exposure to microplastics and copper elicited size-dependent uptake and toxicity responses in red swamp crayfish (Procambarus clarkia)

Scientists exposed red swamp crayfish to microplastics of two sizes combined with copper, finding that smaller microplastics increased copper accumulation in tissues and caused more organ damage. The combined exposure reduced antioxidant defenses and disrupted genes that help regulate copper in the body. Since crayfish is widely consumed, this study raises concerns that microplastics in waterways could increase the amount of toxic metals that accumulate in popular seafood.

2025 Journal of Hazardous Materials 7 citations
Article Tier 2

Influences of Aquaponics System on Growth Performance, Antioxidant Parameters, Stress Parameters and Gene Expression of Carassius auratus

Researchers evaluated the effects of an aquaponics system on the growth performance, antioxidant parameters, stress markers, and gene expression of crucian carp compared to conventional aquaculture conditions, including hypoxia stress trials. The study found that aquaponics influenced fish welfare and physiological status, providing insight into how integrated farming systems affect stress responses in cultured fish.

2023 Fishes 5 citations
Article Tier 2

Accumulation of polyethylene microplastics induces oxidative stress, microbiome dysbiosis and immunoregulation in crayfish

Researchers exposed crayfish (Procambarus clarkii) to polyethylene microplastics through their diet for 21 days and found that particles accumulated in the intestine, hepatopancreas, gills, and blood, persisting even after a week of depuration in clean water. The accumulated microplastics caused oxidative stress, disrupted the gut microbiome, and altered immune regulation. The study suggests that microplastic exposure may compromise the health and immune defenses of commercially important freshwater crustaceans.

2022 Fish & Shellfish Immunology 60 citations
Article Tier 2

Comparison of Intestinal Bacteria of Procambarus clarkii Farmed in Various Rice Paddy Regions

Researchers analyzed gut microbiota in red swamp crayfish (Procambarus clarkii) farmed across different rice paddy regions of China, finding significant regional differences in intestinal bacterial communities linked to local environmental conditions.

2024 Animals 5 citations
Article Tier 2

The Combined Effects of Toxic Microcystis aeruginosa and Thermal Stress on the Edible Clam (Corbicula fluminea): Insights into Oxidative Stress Responses and Molecular Networks

Researchers exposed the edible clam Corbicula fluminea to combined thermal stress and toxic Microcystis aeruginosa cyanobacteria, finding that the combined stressors caused greater oxidative stress and physiological disruption than either alone, with implications for bivalve aquaculture during cyanobacterial bloom events.

2023 Antioxidants 3 citations
Article Tier 2

The effect of a polystyrene nanoplastic on the intestinal microbes and oxidative stress defense of the freshwater crayfish, Procambarus clarkii

Researchers tested the acute effects of polystyrene nanoplastics on freshwater crayfish and found that exposure altered the composition of intestinal bacteria and disrupted oxidative stress defenses. Higher concentrations of nanoplastics led to more severe changes in gut microbial diversity and antioxidant enzyme activity. The study adds to growing evidence that nanoplastic pollution can harm the gut health and immune defenses of freshwater organisms.

2022 The Science of The Total Environment 84 citations
Article Tier 2

H2O2-Induced Oxidative Stress Responses in Eriocheir sinensis: Antioxidant Defense and Immune Gene Expression Dynamics

This study examined how Chinese mitten crabs respond to oxidative stress caused by hydrogen peroxide, finding that their antioxidant defenses and immune gene activity initially ramp up but then collapse under prolonged or high-dose exposure. While not directly about microplastics, the findings are relevant because microplastics are known to trigger similar oxidative stress in aquatic organisms, and this research helps map the biological pathways involved.

2024 Antioxidants 21 citations
Article Tier 2

Effects of nanoplastic exposure on the immunity and metabolism of red crayfish (Cherax quadricarinatus) based on high-throughput sequencing

Researchers examined nanoplastic effects on red crayfish using transcriptomics and microbiome analysis, finding that high concentrations suppressed antioxidant and immune responses while significantly altering gut microbial communities.

2022 Ecotoxicology and Environmental Safety 25 citations
Article Tier 2

Effects of soil trace metals, organic carbon load and physicochemical stressors on active oxygen species metabolism in Scylla serrata sampled along the Bay of Bengal in Odisha state, India

Researchers examined how soil trace metals (calcium and magnesium), organic carbon load, and physicochemical water stressors influence oxidative stress and antioxidant parameters in the edible mud crab Scylla serrata sampled from multiple sites along the Bay of Bengal in Odisha, India. The study found significant spatio-temporal variation in oxidative stress markers across sites with differing environmental conditions, suggesting that combined soil and water quality parameters drive oxidative stress in this ecologically and economically important crab species.

2022 Frontiers in Environmental Science 9 citations
Article Tier 2

Different geographical environment can affect the fatty acid compositions of the Red Swamp Crayfish (Procambarus clarkii) through the intestinal flora

Not relevant to microplastics — this study examines how geographic environment and gut microbiota influence the fatty acid composition and nutritional quality of red swamp crayfish (Procambarus clarkii).

2023 Research Square (Research Square)
Article Tier 2

Transcriptome Analysis of Gills Provides Insights Into Translation Changes Under Hypoxic Stress and Reoxygenation in Golden Pompano, Trachinotus ovatus (Linnaeus 1758)

This transcriptome study found that oxygen deprivation suppresses immune genes in the gills of golden pompano fish, potentially explaining why fish are more susceptible to infections under low-oxygen aquaculture conditions. The molecular findings support improved oxygen management practices in fish farming to protect both animal welfare and food quality.

2021 Frontiers in Marine Science 21 citations
Article Tier 2

Oxidative stress and histopathological effects by microplastic beads, in the crayfish Procambarus clarkii, and fiddler crab Leptuca pugilator

Researchers exposed crayfish and fiddler crabs to polystyrene microplastic beads for one month and examined the effects on their hepatopancreas, a key digestive organ. Both species showed signs of oxidative stress and tissue damage, with microplastic particles accumulating in their organs. The study provides evidence that even at moderate concentrations, microplastic exposure can cause measurable physiological harm to freshwater and coastal crustaceans.

2023 Chemosphere 19 citations
Article Tier 2

Orally administered nano-polystyrene caused vitellogenin alteration and oxidative stress in the red swamp crayfish (Procambarus clarkii)

Researchers orally dosed red swamp crayfish with 100 nm carboxylated polystyrene nanoparticles and found mild but measurable stress responses including altered gene expression in immune function, oxidative stress pathways, lipid metabolism, and reproduction, suggesting nanoplastics can perturb molecular systems even at low concentrations without breaching physiological thresholds.

2021 The Science of The Total Environment 38 citations
Article Tier 2

Distinct Gene Expression Patterns of Two Heat Shock Protein 70 Members During Development, Diapause, and Temperature Stress in the Freshwater Crustacean Daphnia magna

This study examined how two heat shock protein genes respond during the life cycle, dormancy, and temperature stress of the water flea Daphnia magna. Heat shock proteins help organisms tolerate environmental stress, including exposure to toxic pollutants like microplastics, making Daphnia a useful model for ecotoxicology research.

2021 Frontiers in Cell and Developmental Biology 14 citations
Article Tier 2

Effects of Acute Ammonia Stress on Antioxidant Responses, Histopathology and Ammonia Detoxification Metabolism in Triangle Sail Mussels (Hyriopsis cumingii)

Triangle sail mussels exposed to sub-lethal ammonia concentrations showed antioxidant enzyme activation followed by inhibition, with the highest stress responses in gills and hepatopancreas and histopathological damage suggesting oxidative stress as a key mechanism of ammonia toxicity.

2021 Water 35 citations