We can't find the internet
Attempting to reconnect
Something went wrong!
Hang in there while we get back on track
Papers
61,005 resultsShowing papers similar to Transcriptomic Analysis Provides Insights into Candidate Genes and Molecular Pathways Involved in Growth of Mytilus coruscus Larvae
ClearPhysiological and transcriptome analysis of Mytilus coruscus in response to Prorocentrum lima and microplastics
The combined effects of diarrhetic shellfish toxin and microplastics on the mussel Mytilus coruscus were assessed at physiological and transcriptomic levels, revealing synergistic disruption of immune function, antioxidant responses, and metabolic pathways. The study provides molecular-level evidence of interactive toxicity between two common coastal contaminants.
Uptake and transcriptional effects of polystyrene microplastics in larval stages of the Mediterranean mussel Mytilus galloprovincialis
Researchers exposed larval stages of a marine organism to polystyrene microplastics and measured gene expression changes, finding tissue-dependent transcriptional responses that suggest microplastics can affect development even at early life stages.
Single and repetitive microplastics exposures induce immune system modulation and homeostasis alteration in the edible mussel Mytilus galloprovincialis
Researchers examined transcriptome-wide gene expression changes in Mediterranean mussels after single and repeated microplastic exposures, finding significant immune system modulation and disruption of cellular homeostasis. The study suggests that both short-term and chronic microplastic exposure can alter immune regulation pathways in filter-feeding bivalves, with repeated exposures showing cumulative effects.
Distinguish the toxic differentiations between acute exposure of micro- and nano-plastics on bivalves: An integrated study based on transcriptomic sequencing
Researchers found that nanoplastics are more toxic than microplastics in mussels, causing severe inflammatory responses and greater oxidative stress, with transcriptomic analysis revealing contrasting gene expression patterns between the two particle sizes.
Application of transcriptome profiling to inquire into the mechanism of nanoplastics toxicity during Ciona robusta embryogenesis
Transcriptome profiling of marine mussels exposed to amino-modified polystyrene nanoplastics was used to develop an adverse outcome pathway (AOP), revealing disruption of immune function, energy metabolism, and cytoskeletal integrity as key molecular events. The integrative approach provides a mechanistic framework for predicting nanoplastic hazards in marine invertebrates.
Polyethylene microbeads induce transcriptional responses with tissue-dependent patterns in the mussel Mytilus galloprovincialis
Researchers exposed fish to polyethylene microbeads and measured gene expression across tissues, finding tissue-dependent transcriptional responses that suggest microplastic ingestion affects multiple physiological systems in distinct ways.
Different recovery patterns of the surviving bivalve Mytilus galloprovincialis based on transcriptome profiling exposed to spherical or fibrous polyethylene microplastics
Researchers used gene expression analysis to study how Mediterranean mussels respond to and recover from exposure to different shapes of polyethylene microplastics. They found that spherical and fibrous particles triggered distinct stress responses and different recovery patterns over a 14-day period. The study suggests that the shape of microplastics matters significantly in determining their biological impact on marine organisms.
[Physiological and Ecological Response Characteristics and Transcriptomic Change Characteristics of Rice （Oryza sativa）Under Different Microplastic Stresses].
Researchers used transcriptomic analysis to characterize physiological and ecological response characteristics of an aquatic organism exposed to microplastic stress, identifying gene expression changes in pathways related to immune function, oxidative stress, and energy metabolism.
Profiling of microRNAs and mRNAs in marine mussel Mytilus galloprovincialis
Researchers used deep sequencing to profile microRNAs in the Mediterranean blue mussel Mytilus galloprovincialis, identifying 137 miRNA sequences — 104 conserved across species and 33 potentially novel — providing a genomic baseline for studying how this ecologically important species responds to environmental stressors.
Unraveling the interplay between environmental microplastics and salinity stress on Mytilus galloprovincialis larval development: A holistic exploration
Researchers studied how environmental microplastics and increased salinity together affect the early development of Mediterranean mussel larvae. The combination caused larval deformities, developmental problems, and changes in gene activity related to shell formation, stress response, and cell damage. These findings are concerning because climate change is altering ocean salinity in coastal areas where microplastic pollution is also heavy, and mussels are a food source that could pass accumulated microplastics to humans.
Exploring the Potential of Metatranscriptomics to Describe Microbial Communities and Their Effects in Molluscs
Metatranscriptomics revealed a more complete picture of mussel microbiomes — including bacteria, viruses, fungi, and protozoans — than traditional 16S sequencing alone. The approach also identified host genes whose expression changed with pathogen load, providing new insights into how molluscs respond to microbial infections.
Responses of microRNA in digestive glands of mussel Mytilus galloprovincialis exposed to polystyrene nanoplastics
Polystyrene nanoplastics triggered significant microRNA expression changes in the digestive glands of the mussel Mytilus galloprovincialis, with altered miRNAs involved in immune regulation, apoptosis, and stress response pathways. The findings indicate that microRNA-mediated gene regulation is an important molecular mechanism of nanoplastic toxicity in marine bivalves.
Omics insights in responses of bivalves exposed to plastic pollution
This review examined how advanced molecular analysis technologies are being used to understand how bivalves like mussels and oysters respond to microplastic and nanoplastic exposure at the genetic and protein level. Researchers found that plastic pollution disrupts bivalve behavior, metabolism, and reproduction, and that molecular-level analysis can reveal early warning signs of harm not visible through traditional observation. The findings are relevant to both marine conservation and human food safety, since bivalves are widely consumed seafood that accumulate plastic particles.
Microplastics induce dose-specific transcriptomic disruptions in energy metabolism and immunity of the pearl oyster Pinctada margaritifera
Pearl oysters (Pinctada margaritifera) exposed to three doses of polystyrene microbeads showed dose-dependent reductions in energy balance, and transcriptomic analysis revealed disruptions to pathways controlling immunity and energy metabolism that scaled with exposure concentration.
Using Biometrics, Behavioral Observations, and Multiple Molecular Techniques to Assess the Impacts of Changes in Temperature and Salinity on the Common Bay Mussel (Mytilus trossulus)
This study used multiple molecular and physiological techniques to assess how the common bay mussel responds to changes in temperature and salinity, providing baseline data for understanding climate change impacts. Mussels are also used as sentinel organisms for monitoring microplastic contamination in coastal waters.
Identification of microRNA-mRNA regulatory network associated with microplastic exposure in Mytilus galloprovincialis
Scientists identified specific microRNA-mRNA regulatory networks in Mediterranean mussels that are altered by microplastic exposure, revealing how plastic pollution affects gene regulation at the molecular level. The study found that microplastics disrupt biological pathways related to development, growth, and reproduction in these filter-feeding organisms. Since mussels are widely consumed as seafood, the findings also raise concerns about microplastics entering the human food chain.
Effects of Ocean Acidification and Microplastics on Microflora Community Composition in the Digestive Tract of the Thick Shell Mussel Mytilus coruscus Through 16S RNA Gene Sequencing
This study used 16S rRNA gene sequencing to examine how ocean acidification and microplastic exposure, alone and combined, altered the gut microbiome of the thick shell mussel Mytilus coruscus. Both stressors shifted the composition of beneficial gut bacteria, suggesting that these two marine environmental threats can together compromise mussel digestive health.
The Next Generation Is Here: A Review of Transcriptomic Approaches in Marine Ecology
This review assessed transcriptomic approaches in marine ecology, highlighting how next-generation sequencing technologies are enabling researchers to address ecological questions including organism responses to environmental stressors at the molecular level.
Transcriptomic analysis of oxidative stress mechanisms induced by acute nanoplastic exposure in Sepia esculenta larvae
Researchers used transcriptomic analysis to reveal that acute nanoplastic exposure in cuttlefish larvae triggered oxidative stress through disruption of antioxidant enzyme gene expression, identifying key molecular pathways affected by plastic pollution in marine cephalopods.
Revealing the Impact of Polystyrene Nanoplastics on Gill Tissues of the Intertidal Clam, Gafrarium Divaricatum (Gmelin, 1791) using Transcriptomics Approach
Researchers exposed intertidal clams to polystyrene nanoplastics and used transcriptomics to assess gill tissue impacts, finding 1,182 upregulated and 1,626 downregulated genes related to immune modulation, antioxidant defense, and apoptosis. Histopathological examination revealed structural damage to gill tissues including ciliary erosion, lamellae fusion, and lipofuscin accumulation. The study establishes a high-quality genomic resource for this clam species while demonstrating the ecotoxicological effects of nanoplastics on sessile marine bivalves.
Effect of aging of microplastics on gene expression levels of the marine mussel Mytilus edulis: Comparison in vitro/in vivo exposures
Researchers compared the effects of aged versus non-aged polyethylene microplastics on the marine mussel Mytilus edulis using both in vitro and in vivo exposures at environmentally relevant concentrations. The study found that gene expression changes in xenobiotic defense, immune function, and cell cycle control differed depending on whether the plastic was aged and the type of exposure method used. These findings highlight that the environmental weathering state of microplastics is an important factor in determining their biological effects on marine organisms.
Molecular mechanisms controlling physiological plasticity in marine mussels under the influence of natural and anthropogenic stress factors
This thesis project investigated the molecular mechanisms that help Mediterranean mussels cope with environmental stress, including both natural factors and emerging pollutants like microplastics. Understanding these stress responses could help predict how marine shellfish will fare as pollution and climate change intensify.
Transcriptomics-Based Evaluation of the Effects of Polyethylene Microplastics on Pleurotus pulmonarius
Researchers examined the effects of polyethylene microplastics at different concentrations and particle sizes on the edible mushroom Pleurotus pulmonarius, finding that smaller particles caused greater reductions in fresh weight, and using confocal microscopy to confirm uptake of PE-MPs by fungal hyphae. Transcriptomic analysis revealed stress mechanisms at the molecular level, providing the first investigation of microplastic impacts on this commercially important crop.
Immunological Responses of Marine Bivalves to Contaminant Exposure: Contribution of the -Omics Approach
This review examines how contaminant exposure, including emerging pollutants like microplastics, affects the immune responses of marine bivalves using omics-based approaches. Researchers found that combining transcriptomic, proteomic, and metabolomic data provides a more comprehensive picture of how pollutants disrupt bivalve immunity than traditional single-endpoint studies. The study highlights bivalves as valuable sentinel organisms for monitoring the immunological impacts of marine pollution.