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61,005 resultsShowing papers similar to The Influence of Ultra-Processed Food on Colorectal Cancer: A Systematic Review
ClearUltra-processed food exposure and adverse health outcomes: umbrella review of epidemiological meta-analyses
This umbrella review of epidemiological studies examines the health effects of ultra-processed foods, which are a significant source of human microplastic exposure due to plastic packaging. Ultra-processed foods have been linked to a wide range of adverse health outcomes in population studies. The connection between processed food packaging and microplastic contamination adds another dimension to why reducing ultra-processed food consumption may benefit health.
The Impact of Ultra-Processed Foods on Nutritional Quality, Food Safety and Human Health
This review examines how ultra-processed foods affect nutritional quality and food safety, including the leaching of chemical additives and microplastics from food packaging into highly processed food products, and discusses implications for human health from combined dietary exposures.
The clinical relevance of microplastic exposure on colorectal cancer: A systematic review
This systematic review of four studies found that microplastic accumulation in colorectal cancer tissue (25.9-32.2 particles/g) was significantly higher than in healthy controls, with polyamide, polycarbonate, and polypropylene as the most common polymers detected. While a causal relationship has not been established, the evidence points to microplastics as a potential environmental factor in colorectal cancer development.
Ultra-processed foods and cardiometabolic health: public health policies to reduce consumption cannot wait
Researchers argue that the strong and growing evidence linking ultra-processed foods to heart disease, diabetes, and other metabolic conditions justifies immediate public health action. Ultra-processed foods may cause harm through multiple pathways, including their plastic packaging, chemical additives, and poor nutritional quality. The authors stress that waiting for complete scientific understanding of every mechanism should not delay policies to reduce consumption of these foods.
Role of dietary nutrients and metabolism in colorectal cancer.
This review examines how dietary nutrients including glucose, amino acids, lipids, vitamins, and prebiotics may influence colorectal cancer risk and progression. The study discusses metabolic interactions between tumor cells, the tumor microenvironment, and gut microbiota, suggesting that nutritional factors play a meaningful role in shaping these complex biological processes.
Why Is Colorectal Cancer Occurring Earlier? Metabolic Dysfunction, Underrecognized Carcinogens, and Emerging Controversies
Researchers reviewed the rising incidence of early-onset colorectal cancer in people under 50, synthesizing epidemiological, molecular, and multi-omics evidence that implicates metabolic dysfunction, accelerated epigenetic aging, gut microbiome dysbiosis, and modern environmental exposures including micro- and nanoplastics as converging contributors to this trend.
Microplastics and Colorectal Cancer: Presence in Human Colorectal Tissues and Associations with Tumor Biology- A Systematic Review
This review of 13 studies found that tiny plastic particles called microplastics are present in human colon tissues, with higher amounts found in cancerous tumors compared to healthy tissue. The research suggests these plastic particles may contribute to colon cancer development by causing inflammation and creating conditions that help tumors grow. While more research is needed to prove a direct cause-and-effect relationship, this highlights growing concerns about how plastic pollution in our environment and food supply might affect human health.
Invisible invaders: unveiling the carcinogenic threat of microplastics and nanoplastics in colorectal cancer-a systematic review
This systematic review examines the potential link between microplastics and nanoplastics and colorectal cancer. The research highlights how these tiny particles may contribute to cancer development through mechanisms like chronic inflammation and cellular damage in the gut. While more studies are needed, the findings raise important questions about the long-term consequences of ingesting plastic particles.
The Impact of the Gut Microbiome, Environment, and Diet in Early-Onset Colorectal Cancer Development
This review explores why colorectal cancer is increasing among younger people, pointing to changes in gut bacteria, diet, and environmental exposures as likely contributors. Microplastics are discussed as one of several environmental factors that may be disrupting the gut microbiome and promoting inflammation linked to cancer development. The findings suggest that the rising tide of environmental contaminants, including microplastics, could be playing a role in this troubling health trend.
Could Microplastics Be a Driver for Early Onset Colorectal Cancer?
This paper explores whether microplastics could be contributing to the rising rates of colorectal cancer in people under 50. The timing of this increase lines up with the mass production of plastics starting in the 1950s, and microplastics are known to disrupt the gut lining and interact with gut bacteria in ways that could promote cancer. While not proven, the authors argue this connection deserves urgent research given how much plastic humans now ingest.
Microplastic Exposure and Its Dual Impact on Metabolic Syndrome and Pathways of Colorectal Carcinogenesis: A Systematic Review of Epidemiological, Experimental, and Mechanistic Evidence
This systematic review examines evidence linking microplastic exposure to both metabolic syndrome and colorectal cancer pathways. It found a biologically plausible connection between microplastic exposure and these conditions, though a direct clinical link to cancer has not yet been established.
Microplastics and the Rising Tide of Early‐Onset Colorectal Cancer: Exploring the Environmental Gut Connection
This paper explores the potential connection between microplastic exposure and the rising rates of early-onset colorectal cancer. The study discusses how microplastics may interact with the gut environment, suggesting that further research is needed to understand whether environmental microplastic contamination could be contributing to this emerging health trend.
Image 3_Invisible invaders: unveiling the carcinogenic threat of microplastics and nanoplastics in colorectal cancer-a systematic review.png
This systematic review examines the potential link between microplastics and colorectal cancer. It found that humans ingest over 70,000 microplastic particles annually, and that higher concentrations of micro- and nanoplastics have been observed in colorectal tumor tissues compared to healthy tissue, suggesting a possible connection worth further investigation.
Image 2_Invisible invaders: unveiling the carcinogenic threat of microplastics and nanoplastics in colorectal cancer-a systematic review.png
This systematic review examines the potential link between microplastics and colorectal cancer. It found that humans ingest over 70,000 microplastic particles annually, and that higher concentrations of micro- and nanoplastics have been observed in colorectal tumor tissues compared to healthy tissue, suggesting a possible connection worth further investigation.
Image 1_Invisible invaders: unveiling the carcinogenic threat of microplastics and nanoplastics in colorectal cancer-a systematic review.png
This systematic review examines the potential link between microplastics and colorectal cancer. It found that humans ingest over 70,000 microplastic particles annually, and that higher concentrations of micro- and nanoplastics have been observed in colorectal tumor tissues compared to healthy tissue, suggesting a possible connection worth further investigation.
Orally Ingested Micro- and Nano-Plastics: A Hidden Driver of Inflammatory Bowel Disease and Colorectal Cancer.
This review synthesizes evidence linking ingested micro- and nano-plastics to inflammatory bowel disease and colorectal cancer risk, proposing that microplastics act as a hidden driver of gut inflammation in vulnerable populations. The authors argue that intestinal accumulation of microplastics triggers immune and oxidative stress pathways that contribute to disease progression.
Don't take this lying down: an urgent wakeup call: the weight of diet and lifestyle in the young‐onset colorectal cancer surge
This editorial discusses the rise of young-onset colorectal cancer (YO-CRC) in developed nations, noting that CRC is projected to become the leading cause of cancer mortality in those aged 20–49 by 2030, and examines the role of diet, lifestyle, and environmental factors including potential contributions from microplastics. It calls for urgent research and preventive action targeting modifiable risk factors in young adults.
The colorectal cancer conundrum: the rising burden in younger adults
Researchers analyzing 2025 U.S. cancer statistics found that colorectal cancer incidence is rising, with a notable shift toward younger adults and women — a trend that has accelerated in recent decades and is not fully explained by known risk factors. This changing demographic pattern raises questions about emerging environmental or lifestyle exposures, including potential roles for microplastics and endocrine-disrupting chemicals.
Cancer and Food-Related Risks: A Review
This review examines the relationship between diet, food-related environmental exposures, and cancer risk, covering evidence for carcinogenic dietary patterns, contaminants in food including persistent organic pollutants and heavy metals, and the emerging concern of microplastics as potential carcinogens. The authors emphasize that dietary risk is multi-factorial and that improving food safety standards remains a key prevention lever.
Associations between microplastics in human feces and colorectal cancer risk
In a study of 258 colorectal cancer patients and 493 healthy controls, researchers found significantly higher levels of microplastics in the stool of cancer patients, with those in the highest exposure group having 11 times the odds of colorectal cancer. This is one of the first studies in humans to provide epidemiological evidence of a potential link between microplastic exposure and cancer risk, though more research is needed to determine if the relationship is causal.
Chemoprophylaxis of precancerous lesions in patients who are at a high risk of developing colorectal cancer (Review)
This review covers chemoprevention strategies for precancerous lesions in patients at elevated cancer risk, evaluating evidence for pharmacological and dietary interventions including natural compounds that modulate carcinogenic pathways. The authors assess clinical trial evidence and identify specific compounds with strong evidence for reducing progression from precancerous to malignant lesions.
The incidence of early onset colorectal cancer in Aotearoa New Zealand: 2000–2020
Researchers analyzed colorectal cancer trends in New Zealand from 2000 to 2020, finding that while overall rates declined slightly, early-onset cases (in younger adults) are rising — and rising faster among Maori — suggesting environmental or lifestyle factors, including dietary contaminants, may be contributing to this shift.
Associations between ultra-processed foods intake and preserved ratio impaired spirometry in U.S. adults
Researchers analyzed data from U.S. adults and found that higher intake of ultra-processed foods was associated with an increased risk of impaired lung function. The association was particularly notable in individuals with occupational exposure to respiratory hazards. While the study focused on diet and lung health rather than microplastics directly, ultra-processed foods are a known source of microplastic exposure, adding another dimension to concerns about highly processed food consumption.
Detection of Microplastics in Patients with Colorectal Adenocarcinoma using Various Techniques
Researchers detected microplastics in tumoral and non-tumoral colon tissues of colorectal adenocarcinoma patients and healthy controls using ATR-FTIR and Raman spectroscopies, finding that tumoral tissues contained significantly higher microplastic counts than non-tumoral or healthy tissues. The identified polymers included polyethylene, poly(methyl methacrylate), and nylon, suggesting a potential link between microplastic exposure and colorectal cancer.