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20 resultsShowing papers similar to Science-based evidence on pathways and effects of human exposure to micro- and nanoplastics
ClearImpact of microplastics and nanoplastics on human Health: Emerging evidence and future directions
This review summarizes current evidence on how micro- and nanoplastics enter the human body through food, air, and skin contact, and the cellular damage they may cause. While microplastic pollution is a recognized environmental hazard, the authors note that definitive evidence linking plastic particle exposure to specific health outcomes in humans is still limited and more realistic exposure studies are needed.
Exposure scenarios for human health risk assessment of nano- and microplastic particles
This paper focuses on developing realistic exposure scenarios for assessing human health risks from nano- and microplastic particles. Establishing accurate models of how much plastic people actually encounter through food, air, and water is a critical step for determining whether current exposure levels pose real health dangers.
A review of data for quantifying human exposures to micro and nanoplastics and potential health risks
This review synthesizes data on human exposure to micro- and nanoplastics through air, water, and food, and examines the potential health effects. Researchers found evidence of respiratory, liver, immune, and gastrointestinal impacts in humans and mammals exposed to elevated plastic particle levels, with toxicity varying by plastic type and size. The study highlights that while growing evidence links plastic particle exposure to health concerns, significant data gaps remain in quantifying actual human intake and long-term risks.
Micro- and nanoplastics: origin, sources of intake and impact on human health (literature review)
This literature review synthesizes mechanisms by which micro- and nanoplastics interact with living organisms, examining their physicochemical properties, routes of human exposure, and documented health effects across multiple organ systems.
Partial Scoping Review of Microplastic Exposure Publications
This scoping review maps the growing body of research on human microplastic exposure, covering how plastics enter food, water, and air. It identifies key gaps in the literature and highlights the need for standardized methods to better assess real-world human exposure levels.
Knowledge gaps on micro and nanoplastics and human health: A critical review
This critical review assessed current evidence on micro- and nanoplastic exposure and human health, concluding that while humans are ubiquitously exposed via food, water, and air, the long-term health effects of chronic low-level exposure remain poorly understood.
Microplastics And Nanoplastics: Environmental Sources, Human Exposure Pathways, And Potential Health Impacts
This systematic review maps out the many ways microplastics and nanoplastics enter the human body, including through food, water, air, and everyday products. The researchers found these tiny particles are now present in nearly every environment, from oceans to our homes. The review highlights growing concerns about what this constant low-level exposure might mean for our long-term health.
Integrating aggregate exposure pathway and adverse outcome pathway for micro/nanoplastics: A review on exposure, toxicokinetics, and toxicity studies
This review brings together research on how micro and nanoplastics enter the human body, where they go once inside, and what harm they may cause, using a framework that links exposure pathways to health outcomes. Studies show these tiny particles can be absorbed through the gut, lungs, and skin, and may accumulate in organs like the liver and kidneys. The paper highlights that micro and nanoplastics can trigger inflammation, oxidative stress, and disruption of hormones, though more research is needed to fully understand the long-term health risks.
Exposure Pathways, Systemic Distribution, and Health Implications of Micro- and Nanoplastics in Humans
This review summarizes how micro- and nanoplastics enter the human body through food, air, and skin, then distribute to organs throughout the body. Research in animal and cell models shows these particles can cause oxidative stress, inflammation, brain toxicity, reproductive problems, and potentially cancer, though standardized methods for assessing real-world human health risks are still needed.
The exposure routes of micro- and nanoplastics and their potential toxic effects on human health
This review summarized current knowledge about how micro- and nanoplastics enter the human body through breathing, eating, and skin contact. The study discusses evidence from laboratory and animal studies suggesting these particles may affect the reproductive, respiratory, digestive, and immune systems, though researchers note that more human studies are needed to fully understand the health implications.
Exposure sources and pathways of micro- and nanoplastics in the environment, with emphasis on potential effects in humans: A systematic review
This systematic review maps out all the ways humans are exposed to microplastics — through drinking water, food, and the air we breathe. The research highlights that current water treatment technology does not fully filter out microplastics, and their accumulation in the body may pose risks to human health.
Understanding the human health impacts of environmental micro- and nanoplastics
This review summarized current understanding of how micro- and nanoplastic particles enter the human body through food and air, accumulate in tissues, and cause health effects through oxidative stress, inflammation, and endocrine disruption, with a focus on gaps in knowledge about long-term human health impacts.
Microplastics and Human Health: A Comprehensive Review on Exposure Pathways, Toxicity, and Emerging Risks
This comprehensive review examines microplastic exposure pathways in humans, methods of detection, and the potential toxic effects on various biological systems. The study highlights growing evidence that microplastics can enter the body through ingestion, inhalation, and dermal contact, and may affect multiple organ systems, though significant uncertainties remain about long-term health outcomes.
Eco-toxicity of nano-plastics and its implication on human metabolism: Current and future perspective
This review examines the sources, bioaccumulation pathways, and potential health effects of nanoplastics on human metabolism. Researchers found that nanoplastics can enter the body primarily through ingestion of contaminated food and packaging, and evidence suggests they may interfere with metabolic pathways and contribute to organ dysfunction. The study highlights that significant knowledge gaps remain in assessing the human health risks of nanoplastic exposure.
The current status of studies of human exposure assessment of microplastics and their health effects: a rapid systematic review
This rapid systematic review summarizes what is known about human exposure to microplastics and potential health effects based on studies published from 2000 to 2019. The researchers found that there is no standardized method for measuring microplastic exposure in humans, making it difficult to compare studies or draw firm conclusions. Despite the gaps, the available evidence suggests that people are regularly exposed to microplastics through food, water, and air, and more research is urgently needed on health effects.
A review on microplastics and nanoplastics in the environment: Their occurrence, exposure routes, toxic studies, and potential effects on human health
This review summarizes what is known about how microplastics and nanoplastics enter the human body through food, air, and skin contact, and what they do once inside. Studies on cells and animals show these tiny particles can cause oxidative stress, DNA damage, inflammation, and harm to the immune, digestive, reproductive, and nervous systems. The research makes clear that microplastics are not just an environmental problem but a direct concern for human health.
Scientific Evidence about the Risks of Micro and Nanoplastics (MNPLs) to Human Health and Their Exposure Routes through the Environment
Researchers reviewed the scientific evidence on exposure routes and health risks of micro- and nanoplastics to humans through environmental pathways. The study examined how plastic particles found in soil, water, and air enter the body primarily through ingestion and inhalation, and how they interact with the gastrointestinal tract. Evidence indicates that these particles can adsorb additives, heavy metals, and microorganisms on their surfaces, potentially contributing to toxic effects.
A critical review of micro- and nanoplastic permeation in the human body
This critical review examines how micro- and nanoplastics enter and move through the human body after exposure through food, beverages, and air. Researchers synthesized evidence showing these particles have been detected in multiple human tissues and organs, raising concerns about their potential long-term health effects from chronic environmental exposure.
Towards a risk assessment framework for micro- and nanoplastic particles for human health
This review proposes a framework for assessing the health risks of micro- and nanoplastics to humans, noting that current methods are inadequate because these particles come in countless types, sizes, and chemical compositions. The authors recommend focusing first on inhalation risks and suggest using existing approaches for evaluating low-toxicity particles and fibers as a starting point for plastic particle safety standards.
Human exposure to micro- and nanoplastic: biological effects and health consequence
This review summarized the biological effects and health consequences of human exposure to micro- and nanoplastics, covering routes of uptake (ingestion, inhalation, dermal), cellular toxicity mechanisms, and systemic health risks identified in recent experimental and epidemiological studies.