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Article Tier 2 Environmental Sources Gut & Microbiome Human Health Effects Marine & Wildlife Nanoplastics Sign in to save

Scientific Evidence about the Risks of Micro and Nanoplastics (MNPLs) to Human Health and Their Exposure Routes through the Environment

Toxics 2022 70 citations

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Researchers reviewed the scientific evidence on exposure routes and health risks of micro- and nanoplastics to humans through environmental pathways. The study examined how plastic particles found in soil, water, and air enter the body primarily through ingestion and inhalation, and how they interact with the gastrointestinal tract. Evidence indicates that these particles can adsorb additives, heavy metals, and microorganisms on their surfaces, potentially contributing to toxic effects.

Nowadays, a large amount and variety of plastic is being produced and consumed by human beings on an enormous scale. Microplastics and nanoplastics (MNPLs) have become ubiquitous since they can be found in many ecosystem components. Plastic particles can be found in soil, water, and air. The routes of human exposure are numerous, mainly involving ingestion and inhalation. Once ingested, these particles interact with the gastrointestinal tract and digestive fluids. They can adsorb substances such as additives, heavy metals, proteins, or even microorganisms on their surface, which can cause toxicity. During inhalation, they can be inhaled according to their respective sizes. Studies have reported that exposure to MNPLs can cause damage to the respiratory tract, creating problems such as bronchitis, asthma, fibrosis, and pneumothorax. The reports of boards and committees indicate that there is little data published and available on the toxicity of MNPLs as well as the exposure levels in humans. Despite the well-established concept of MNPLs, their characteristics, and presence in the environment, little is known about their real effects on human health and the environment.

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