Papers

61,005 results
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Article Tier 2

Inorganic Nanoparticle and Nanoplastic Transformations and the Impact on Biouptake by Freshwater Algal Cells Using Single Cell and Single Particle Inductively Coupled Plasma Mass Spectrometry

This dissertation used single-particle and single-cell ICP-MS to quantify how nanoparticles and nanoplastics transform in the presence of freshwater algae and how those transformations affect biouptake, finding that algal interactions altered particle surface chemistry and changed bioavailability.

2025 Scholar Commons (University of South Carolina)
Article Tier 2

Characterisation of microplastics and unicellular algae in seawater by targeting carbon via single particle and single cell ICP-MS

Researchers used single particle and single cell ICP-MS to characterize microplastics and microalgae simultaneously in seawater by targeting carbon signals, demonstrating the technique as a rapid and sensitive tool for distinguishing plastic particles from biological material.

2021 Analytica Chimica Acta 62 citations
Article Tier 2

Counting Nanoplastics in Environmental Waters by Single Particle Inductively Coupled Plasma Mass Spectroscopy after Cloud-Point Extraction and In Situ Labeling of Gold Nanoparticles

Researchers developed a cloud-point extraction and in-situ gold nanoparticle labeling method combined with single particle ICP-MS to count nanoplastics down to 50 nm in environmental water samples, enabling quantification of nanoplastics previously undetectable by conventional methods.

2021 Environmental Science & Technology 84 citations
Article Tier 2

Investigating the Cellular Uptake of Model Nanoplastics by Single-Cell ICP-MS

Researchers developed gold-doped polyethylene and polyvinyl chloride nanoparticles as model nanoplastics and used single-cell ICP-MS to investigate their cellular uptake. The study demonstrated that this approach enables rapid, high-throughput detection of nanoplastic interactions with cells, providing a valuable tool for understanding how environmentally relevant nanoplastics behave at the cellular level.

2023 Nanomaterials 25 citations
Article Tier 2

A Novel Strategy for the Detection and Quantification of Nanoplastics by Single Particle Inductively Coupled Plasma Mass Spectrometry (ICP-MS)

A new analytical method was developed to detect and count individual nanoplastic particles in drinking water and river water using gold nanoparticles as tags and single particle ICP-MS for detection. The method can detect nanoplastics as small as 135 nm at environmentally relevant concentrations, providing a sensitive new tool for tracking nanoplastic contamination.

2020 Analytical Chemistry 152 citations
Article Tier 2

Quantitative Tracking of Nanoplastic Uptake and Distributionin Zebrafish by Single-Particle Inductively Coupled Plasma Mass Spectrometry

Researchers developed a framework using europium-doped polystyrene nanoplastics as tracers, combined with single-particle inductively coupled plasma mass spectrometry, to quantitatively track nanoplastic uptake and distribution in zebrafish at the single-particle level. This method enabled real-time, size-resolved tracking of nanoplastics accumulating in different fish organs over time.

2025 Figshare
Article Tier 2

Detection, counting and characterization of nanoplastics in marine bioindicators: a proof of principle study

Researchers demonstrated a proof-of-concept workflow for detecting and counting nanoplastic particles (below 1 µm) in marine invertebrate tissues using electron microscopy and spectroscopic confirmation, finding nanoplastics in marine bioindicator species and establishing a methodology for future monitoring programs.

2021 Microplastics and Nanoplastics 46 citations
Article Tier 2

Development of single-cell ICP-TOFMS to measure nanoplastics association with human cells

Researchers developed a new single-cell analytical technique using ICP-TOFMS to measure how nanoplastic particles associate with individual human cells. This method enables detection of nanoplastics at the single-cell level, offering a more precise way to study how these tiny plastic particles interact with human tissues. The approach addresses a critical gap in understanding nanoplastic exposure and uptake in biological systems.

2023 Environmental Science Nano 20 citations
Article Tier 2

Pyrolysis-GC–MS analysis of ingested polystyrene microsphere content in individual Daphnia magna

Researchers developed a pyrolysis-GC-MS method sensitive enough to quantify polystyrene microspheres ingested by individual Daphnia magna, enabling accurate measurement of microplastic uptake in small zooplankton without the interference of organism biomass.

2022 The Science of The Total Environment 27 citations
Article Tier 2

Investigation of Detection Method for Nanoplastics in Shellfish

Researchers investigated detection methods for nanoplastics in shellfish, evaluating analytical techniques capable of identifying and quantifying nanoscale plastic particles in bivalve tissues. The study addresses the methodological challenges of isolating and characterizing nanoplastics from complex biological matrices.

2024 Taipei Medical University Repository
Article Tier 2

Imaging and quantifying the biological uptake and distribution of nanoplastics using a dual-functional model material

Researchers developed a dual-functional nanoplastic model material that allows both imaging and precise quantification of nanoplastic uptake in biological systems. Using surface-enhanced Raman spectroscopy and inductively coupled plasma mass spectrometry, they could track where nanoplastics accumulated in organisms at high resolution. The tool addresses a major gap in nanoplastic research by enabling more accurate measurement of how these tiny particles interact with living tissues.

2024 2 citations
Article Tier 2

Toxicological Evaluation and Quantification of Ingested Metal-Core Nanoplastic by Daphnia magna Through Fluorescence and Inductively Coupled Plasma-Mass Spectrometric Methods

Researchers developed a method using both fluorescence microscopy and ICP-MS to simultaneously quantify nanoplastic particles ingested by Daphnia magna and assess associated toxicity, finding dose-dependent uptake and toxic effects. The combined quantification and toxicity approach provides a more complete picture of nanoplastic risk to freshwater zooplankton than either method alone.

2019 Environmental Toxicology and Chemistry 45 citations
Article Tier 2

An In Situ Depolymerization and Liquid Chromatography–Tandem Mass Spectrometry Method for Quantifying Polylactic Acid Microplastics in Environmental Samples

Researchers developed an in-situ depolymerization combined with liquid chromatography-tandem mass spectrometry method to detect and quantify nanoplastics directly in complex environmental and biological samples. The approach avoided the need for physical isolation of particles and enabled sensitive identification of polymer type and abundance.

2022 Environmental Science & Technology 57 citations
Article Tier 2

Quantitative Analysis of Polystyrene and Poly(methyl methacrylate) Nanoplastics in Tissues of Aquatic Animals

Researchers developed a new method to detect and measure nanoplastics in the tissues of aquatic animals with high sensitivity. Using a combination of tissue digestion and pyrolysis gas chromatography-mass spectrometry, they achieved detection limits as low as 0.03 micrograms per gram for polystyrene nanoplastics. When they tested 14 aquatic animal species, polystyrene nanoplastics were found in three of them, demonstrating that nanoplastic contamination is present in real-world wildlife.

2021 Environmental Science & Technology 112 citations
Article Tier 2

A taste of plastic - quantifying micro- and nanoplastic ingestion and interactions with feeding in daphnia magna (E)

This study developed quantitative methods for measuring microplastic and nanoplastic ingestion by freshwater organisms, applying them to mussels and other invertebrates. The analytical approach helps address a key gap in freshwater microplastic research, where most studies have been qualitative rather than quantitative in assessing organism exposure.

2017 Technical University of Denmark, DTU Orbit (Technical University of Denmark, DTU)
Article Tier 2

Mass spectrometry-based multimodal approaches for the identification and quantification analysis of microplastics in food matrix

This review examines mass spectrometry techniques for identifying and measuring microplastics in food, covering methods that analyze both the chemical composition and quantity of plastic particles. The study suggests these advanced analytical approaches could help bridge the gap between environmental monitoring and understanding actual human exposure levels. Better measurement tools are needed to assess how much microplastic people are consuming through their diet.

2023 Frontiers in Nutrition 27 citations
Article Tier 2

In Situ Identification and Spatial Mapping of Microplastic Standards in Paramecia by Secondary-Ion Mass Spectrometry Imaging

Researchers used secondary-ion mass spectrometry imaging to identify and spatially map microplastic particles inside paramecia, demonstrating that the technique can localize specific polymer types within unicellular organisms at subcellular resolution, offering a new tool for studying how microplastics interact with cell structures.

2021 Analytical Chemistry 31 citations
Article Tier 2

Distribution, bioaccumulation, and trophic transfer of palladium-doped nanoplastics in a constructed freshwater ecosystem

Researchers used palladium-doped nanoplastics as tracers in a constructed freshwater ecosystem to quantitatively track distribution, bioaccumulation, and trophic transfer, finding that nanoplastics move through multiple trophic levels and accumulate in organisms.

2022 Environmental Science Nano 25 citations
Article Tier 2

Nanoplastics prepared with uniformly distributed metal-tags: a novel approach to quantify size distribution and particle number concentration of polydisperse nanoplastics by single particle ICP-MS

Researchers developed a new method for creating nanoplastic test particles with embedded metal tags, allowing scientists to precisely measure the size and number of nanoplastics using single-particle mass spectrometry. The particles have realistic irregular shapes and varied sizes, unlike the uniform spheres typically used in lab studies. This tool will help researchers more accurately study how nanoplastics behave in environmental and health experiments.

2023 Environmental Science Nano 15 citations
Article Tier 2

From the synthesis of labeled nanoplastic model materials (isotopic and metallic) to their use in ecotoxicological studies with the detection and quantification analytical methods.

This study developed labeled nanoplastic model materials using isotopic and metallic tracers to enable tracking and quantification of nanoplastics in complex biological and environmental matrices at environmentally relevant concentrations. Labeled particles allowed localization and measurement of nanoplastics at levels not detectable by conventional methods, advancing mechanistic exposure studies.

2024 Zenodo (CERN European Organization for Nuclear Research)
Article Tier 2

Mass-based trophic transfer of polystyrene nanoplastics in the lettuce-snail food chain

Researchers traced the trophic transfer of polystyrene nanoplastics from water into lettuce plants and then into garden snails, finding measurable mass-based transfer at each step of the food chain even at low nanoplastic concentrations using pyrolysis-GC/MS quantification.

2023 The Science of The Total Environment 16 citations
Article Tier 2

Metal-doping of nanoplastics enables accurate assessment of uptake and effects on Gammarus pulex

Freshwater amphipods (Gammarus pulex) were exposed to palladium-doped nanoplastics via sediment for 28 days; ICP-MS quantification of Pd showed dose-dependent NP accumulation, and chronic exposure at high concentrations caused significant effects on survival and reproduction.

2021 Environmental Science Nano 38 citations
Article Tier 2

In Situ Determination of Chlorella Concentration Using Single Entity Electrochemistry

Researchers developed an electrochemical method for detecting individual algal cells in real time using an ultramicroelectrode and single-particle collision technique. The approach could distinguish individual Chlorella cells and relate collision frequency to algal concentration, offering potential for early detection of harmful algal blooms. While not directly focused on microplastics, the method provides a platform for monitoring water quality impacts related to microplastic-linked eutrophication.

2026 Sensors
Article Tier 2

Micro and Nanoplastics size distribution in mussel tissues: first evidence, identification, and quantification in the nanogram range

Italian researchers used a highly sensitive mass spectrometry technique to detect and quantify both microplastics and nanoplastics in farmed mussels, finding plastic particles in every sample tested. Nanoplastics in the 20–200 nm range were present in substantial quantities, and the authors estimate that European seafood consumers could ingest over 2 milligrams of nanoplastics per year through mussel consumption alone. This is one of the first studies to directly quantify nanoplastics in a commonly eaten seafood, raising significant concerns about dietary exposure.

2023 Research Square (Research Square) 2 citations