Papers

61,005 results
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Article Tier 2

Microplastics as an Emerging Human Health Risk: Mechanisms, Exposure, and Clinical Evidence

This review examines the growing body of evidence on how microplastics enter the human body through ingestion, inhalation, and skin contact, and have now been detected in blood, lung tissue, placenta, and cardiovascular tissue. Evidence indicates that microplastics may cause harm through oxidative stress, inflammation, and cellular damage, though a direct causal link to specific health conditions has not yet been fully established.

2026 Zenodo (CERN European Organization for Nuclear Research)
Article Tier 2

Microplastics as an Emerging Human Health Risk: Mechanisms, Exposure, and Clinical Evidence

This review examines the growing body of evidence on how microplastics enter the human body through ingestion, inhalation, and skin contact, and have now been detected in blood, lung tissue, placenta, and cardiovascular tissue. Evidence indicates that microplastics may cause harm through oxidative stress, inflammation, and cellular damage, though a direct causal link to specific health conditions has not yet been fully established.

2026 Zenodo (CERN European Organization for Nuclear Research)
Article Tier 2

Micro- and Nanoplastics on Human Health and Diseases: Perspectives and Recent Advances

This review provides a comprehensive overview of how micro- and nanoplastics enter the human body through ingestion, inhalation, and skin absorption, and how they can then travel through the bloodstream to reach virtually every organ. Researchers summarize evidence that these particles can trigger inflammation, oxidative stress, and disruption of hormonal and immune functions. The study emphasizes that the ability of these particles to cross biological barriers and accumulate in tissues makes understanding their long-term health effects an urgent research priority.

2025 Microplastics 3 citations
Article Tier 2

Effects of micro-and-nano plastics on various organ systems in health

This review examines the toxicological effects of micro- and nanoplastics on multiple human organ systems—including the gut, liver, lungs, cardiovascular system, and brain—summarizing mechanisms of harm such as oxidative stress, inflammation, and endocrine disruption.

2025
Article Tier 2

Microplastics, Nanoplastics and Heart Contamination: The Hidden Threat

This review examines growing evidence that micro- and nanoplastics can accumulate in human cardiovascular tissues, including blood, heart muscle, and arterial plaques. Researchers found that these particles may contribute to heart and blood vessel problems through inflammation, oxidative stress, blood clotting, and direct tissue injury. The study identifies plastic particles as a potential new environmental risk factor for cardiovascular health.

2025 Journal of Clinical Medicine 2 citations
Article Tier 2

Micro and Nanoplastics on Human Health and Diseases: Perspectives and Recent Advances

This review covers how micro- and nanoplastic particles enter the human body through ingestion, inhalation, infusion, and skin absorption, distribute to virtually all tissues and organs via the circulatory system, and cause health impacts including inflammatory responses, cellular damage, and endocrine disruption.

2025 Preprints.org
Article Tier 2

Adverse Outcome Phenomena and Toxicity Mechanisms of Micro and Nanoplastics in Human Health

This review examines the growing evidence that micro- and nanoplastics can enter the human body through food, water, and air, and may contribute to harmful biological effects. Researchers found that these tiny particles can trigger oxidative stress, inflammation, and disruption of hormonal and immune systems in laboratory studies. The study highlights the need for a unified research approach to better understand how microplastic exposure may affect long-term human health.

2024 Nano LIFE 5 citations
Article Tier 2

Impact of microplastics and nanoplastics on cardiovascular health

This review examines the emerging evidence on how microplastics and nanoplastics may affect cardiovascular health. The study discusses clinical evidence suggesting that these particles can accumulate in the cardiovascular system and highlights possible molecular mechanisms including inflammation and oxidative stress, while noting that current evidence linking microplastics to cardiovascular disease remains largely correlative.

2026 Trends in Cardiovascular Medicine
Article Tier 2

Cellular and Molecular Mechanisms of Micro- and Nanoplastics Driving Adverse Human Health Effects

This review examines the biological mechanisms by which micro- and nanoplastics may cause harm in humans, including oxidative stress, inflammation, disruption of protective barriers, and immune system problems. Evidence from lab and animal studies suggests these particles can affect the gut, heart, brain, and reproductive systems, though human data is still limited to detecting plastics in tissues rather than proving they cause specific diseases. The authors highlight that most studies use higher doses than people actually encounter, making it important to develop research models that better reflect real-world chronic exposure.

2025 Toxics 5 citations
Article Tier 2

Emerging cardiovascular risks of micro- and nanoplastics: toxic effects and mechanistic pathways

Tiny plastic particles called micro- and nanoplastics are getting into our bodies through food, air, and skin contact, and researchers have found them building up in people's hearts and blood vessels. This review of existing studies shows these plastic bits may contribute to heart disease by causing inflammation and damaging cells in the cardiovascular system. While more research is needed, this suggests that plastic pollution isn't just an environmental problem—it could be directly harming our heart health.

2026 Particle and Fibre Toxicology
Article Tier 2

Micro and Nano-plastic particles: What are they and do they effect cardiovascular health?

This review examines the cardiovascular health effects of micro- and nanoplastics, summarizing evidence that these particles have been detected in human tissues including arterial plaques and may promote endothelial dysfunction and inflammation. The authors call for further clinical and epidemiological research into cardiac risk.

2024 Nepal Journal of Epidemiology 1 citations
Review Tier 2

A review on microplastics and nanoplastics in the environment: Their occurrence, exposure routes, toxic studies, and potential effects on human health

This review summarizes what is known about how microplastics and nanoplastics enter the human body through food, air, and skin contact, and what they do once inside. Studies on cells and animals show these tiny particles can cause oxidative stress, DNA damage, inflammation, and harm to the immune, digestive, reproductive, and nervous systems. The research makes clear that microplastics are not just an environmental problem but a direct concern for human health.

2022 Marine Pollution Bulletin 379 citations
Article Tier 2

Exposure Pathways, Systemic Distribution, and Health Implications of Micro- and Nanoplastics in Humans

This review summarizes how micro- and nanoplastics enter the human body through food, air, and skin, then distribute to organs throughout the body. Research in animal and cell models shows these particles can cause oxidative stress, inflammation, brain toxicity, reproductive problems, and potentially cancer, though standardized methods for assessing real-world human health risks are still needed.

2025 Applied Sciences 12 citations
Article Tier 2

The Impact of Microplastic on Human Health

This review synthesized evidence on microplastic exposure pathways and health effects in humans, finding that microplastics enter the body via ingestion, inhalation, and dermal contact and are associated with oxidative stress, inflammation, genotoxicity, and endocrine disruption.

2021 Current Biotechnology 5 citations
Systematic Review Tier 1

Effects of Microplastics on Human Physiology: Mechanisms of Toxicity and Health Risks

This systematic review of 48 studies confirmed that microplastics are present in human blood, placenta, and reproductive tissues. The research consistently shows these particles cause oxidative stress, inflammation, mitochondrial damage, and hormonal disruption, pointing to potential links with reproductive problems, cardiovascular issues, and other chronic health conditions.

2025 INTERNATIONAL JOURNAL OF HEALTH & MEDICAL RESEARCH
Systematic Review Tier 1

A Systematic Review on the Impact of Micro-Nanoplastics Exposure on Human Health and Diseases

This systematic review summarizes existing research on how micro and nanoplastic exposure affects human health and may contribute to disease. The evidence suggests that these tiny particles can enter the body through food, water, air, and even cosmetics, potentially causing inflammation, oxidative stress, and disruptions to the immune and reproductive systems.

2022 Biointerface Research in Applied Chemistry 18 citations
Article Tier 2

Nanoplastics as emerging cardiovascular hazards: a narrative review of current evidence

This review examines the emerging evidence that nanoplastics may pose risks to cardiovascular health. Researchers summarized studies showing that nanoplastics can enter the bloodstream through ingestion, inhalation, and skin contact, potentially causing inflammation and oxidative damage to blood vessels and heart tissue. The study suggests that nanoplastic exposure represents an understudied but potentially significant environmental risk factor for heart and vascular problems.

2024 The Egyptian Journal of Internal Medicine 7 citations
Article Tier 2

Understanding the human health impacts of environmental micro- and nanoplastics

This review summarized current understanding of how micro- and nanoplastic particles enter the human body through food and air, accumulate in tissues, and cause health effects through oxidative stress, inflammation, and endocrine disruption, with a focus on gaps in knowledge about long-term human health impacts.

2025 University of Vienna
Review Tier 2

Potential Health Impact of Microplastics: A Review of Environmental Distribution, Human Exposure, and Toxic Effects

This review summarizes existing research on how microplastics are found throughout the environment and in human samples, entering the body through food, air, and skin contact. Lab studies in cells and animals show microplastics can cause oxidative stress, DNA damage, immune reactions, brain toxicity, and reproductive harm, and early human health data links microplastic exposure to several chronic diseases.

2023 Environment & Health 519 citations
Systematic Review Tier 1

Impacts of micro- and nanoplastic exposure on the cardiovascular system: a systematic review focused on in vivo studies

This systematic review summarizes 38 animal studies on how micro- and nanoplastics affect the heart and blood vessels. The research found that these tiny plastic particles can deposit in cardiovascular tissue, trigger inflammation and oxidative stress, and cause structural damage, raising concerns about potential heart health risks from ongoing plastic exposure.

2024 All Life 6 citations
Article Tier 2

Microplastics and Nanoplastics in Human Health: Toxicological Mechanisms Involving Oxidative Stress, Endocrine Interference, and Inflammatory Responses

Tiny plastic particles called microplastics and nanoplastics are now found everywhere—in our air, water, and food—and this review of existing research shows they may harm our health in three main ways. These particles can damage cells, disrupt hormones, and cause inflammation throughout the body, potentially affecting organs like the heart, liver, and brain. While scientists are still studying exactly how dangerous these plastic particles are to humans, the evidence suggests we should be concerned about our constant exposure to them.

2026 Zenodo (CERN European Organization for Nuclear Research)
Systematic Review Tier 1

Molecular and Cellular Effects of Microplastics and Nanoplastics in the Pathogenesis of Cardiovascular, Nervous, Urinary, Digestive, and Reproductive System Diseases: A Global Systematic Review

This systematic review examines how micro- and nanoplastics cause damage at the cellular level across multiple body systems, including the heart, brain, kidneys, gut, and reproductive organs. The key mechanisms include oxidative stress, inflammation, and disruption of protective barriers in the body, suggesting that ongoing plastic exposure may contribute to a wide range of health problems.

2025 International Journal of Molecular Sciences 1 citations
Article Tier 2

Evidence, Mechanisms, and Clinical Implications of Microplastics and Nanoplastics As Emerging Cardiovascular Risk Factors: A Narrative Review

This review examines growing evidence that micro- and nanoplastics may contribute to cardiovascular health risks, with researchers having found these particles in human artery plaques and blood clots. Evidence indicates that the particles can enter the bloodstream, trigger inflammation, damage blood vessel walls, and potentially increase the risk of heart attacks and strokes. While the evidence is not yet conclusive, the study highlights an emerging area of concern that warrants further investigation into how everyday plastic exposure may affect heart and blood vessel health.

2025 Cureus 2 citations
Article Tier 2

[Human Accumulation and Toxic Effects of Microplastics:A Critical Review].

This review summarizes how microplastics enter the human body through food, drinking water, and air, and where they tend to accumulate in organs and tissues. Researchers found evidence that microplastics can trigger inflammatory responses and oxidative stress in the body. The study calls for more research into the long-term health effects of continuous microplastic exposure in humans.

2024 PubMed 5 citations